Structures of force transduction in cross-striated muscle tissues : protein-protein interactions and mechanisms of their regulation
Strukturen der Kraftübertragung im quergestreiften Muskel : Protein-Protein-Wechselwirkungen und Regulationsmechanismen
|
| Creator(s) |
Gehmlich, Katja
|
| Description |
The cell-matrix-contacts (costameres) and cell-cell-contacts (intercalated discs of cardiomyocytes) of cross-striated muscle cells transmit mechanical forces to the exterior. On top of this mechanical ...
Im Mittelpunkt dieser Arbeit standen Signaltransduktionsprozesse in den Strukturen der Kraftübertragung quergestreifter Muskelzellen, d. h. in den Costameren (Zell-Matrix-Kontakten) und den Glanzstrei ...
|
| Repository |
Publikationsserver der Universitaet Potsdam
Repository Info
|
| Language |
German
|
|
View document details...
|
An XML-based Database of Molecular Pathways
|
| Creator(s) |
Hall, David
|
| Description |
Research of protein-protein interactions produce vast quantities of data and there exists a large number of databases with data from this research. Many of these databases offers the data for download ...
|
| Repository |
Linköping University Electronic Press
Repository Info
|
| Language |
English
|
|
View document details...
|
Luminometric measurement of protein S100 at malignant melanoma
Luminometrische Bestimmung von Protein S100 bei malignem Melanom
|
| Creator(s) |
Reichenauer, Simon
|
| Description |
Prognosis of malignant melanoma is worsened considerably by distant metastasis. Early treatment of this metastasis improves the likelihood of survival and long term prognosis. Therefore the aim of usi ...
Die Prognose des malignen Melanoms wird erheblich von einer Fernmetastasierung verschlechtert. Ein frühzeitiges Therapieren dieser Metastasierung verbessert die Über-lebenswahrscheinlichkeit und Langz ...
|
| Repository |
Online-Publikationsservice der Universitaet Tuebingen
Repository Info
|
| Language |
German
|
|
View document details...
|
Tyrosine phosphorylation of VHR phosphatase by ZAP-70.
|
| Creator(s) |
Mustelin, Tomas
van Stipdonk, Marianne
Alonso, Andres
Rahmouni, Souad
Schoenberger, Stephen P
Abraham, Robert T
Williams, Scott
Jaroszewski, Lukasz
Godzik, Adam
|
| Description |
The ZAP-70 tyrosine kinase is a key component of the signaling machinery for the T cell antigen receptor (TCR). Whereas recruitment and activation of ZAP-70 are relatively well understood, the protein ...
|
| Repository |
ORBi (University of Liège)
Repository Info
|
| Language |
English
|
|
View document details...
|
The significance of quantitative immunhistochemical examination of S100A6 protein in breast cancer
Die Bedeutung des quantitativen immunhistochemischen Nachweises von Protein S100A6 beim Mammakarzinom
|
| Creator(s) |
Gerteis, Andreas
|
| Description |
Protein S100A6 is a member of the Ca2+-binding S100 family. Since it was proved, that in various malignant tumours (e.g. Melanoma and colorectal Adenocarcinoma) overexpression of this protein was rela ...
S100A6 ist ein Mitglied der Protein S100-Familie, die Ca++-Ionen binden können. Seit bei verschiedenen malignen Tumoren (z.B. Melanom und Colonkarzinom) eine Überexpression dieses Proteins mit einer s ...
|
| Repository |
Online-Publikationsservice der Universitaet Tuebingen
Repository Info
|
| Language |
German
|
|
View document details...
|
Lipid raft targeting of hematopoietic protein tyrosine phosphatase by protein kinase C theta-mediated phosphorylation.
|
| Creator(s) |
Baier, Gottfried
Bruckner, Shane
Rahmouni, Souad
Tautz, Lutz
Nika, Konstantina
Charvet, Celine
Schoenberger, Stephen P
Bottini, Nunzio
Altman, Amnon
Williams, Scott
Mustelin, Tomas
|
| Description |
Protein kinase C theta (PKC theta) is unique among PKC isozymes in its translocation to the center of the immune synapse in T cells and its unique downstream signaling. Here we show that the hematopoi ...
|
| Repository |
ORBi (University of Liège)
Repository Info
|
| Language |
English
|
|
View document details...
|
-866G/A polymorphism in the promoter of uncoupling protein 2 - Impact on glucose metabolism
-866G/A Polymorphismus in der Promotorregion von Uncoupling Protein 2 - Auswirkung auf den Glukosemetabolismus
|
| Creator(s) |
Guthoff, Martina
|
| Description |
Uncoupling protein 2 is involved in energy metabolism and in regulating glucose stimulated insulin secretion in pancreatic beta cells. The prevalent -866G/A polymorphism in the promoter of UCP2 has be ...
Bei der Suche nach den genetischen Ursachen des Diabetes mellitus Typ 2 hat sich das Uncoupling Protein 2-Gen, welches für ein Kanalprotein der inneren Mitochondrienmembran kodiert, als interessantes ...
|
| Repository |
Online-Publikationsservice der Universitaet Tuebingen
Repository Info
|
| Language |
German
|
|
View document details...
|
Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae
|
| Creator(s) |
Knudsen, Jens
Larsen, Morten K.
Faergeman, Nils J.
Christiansen, Janne K.
Feddersen, Søren
Schneiter, Roger
Roepstroff, Peter
Ungermann, Christian
Mutenda, Kudzai
|
| Description |
In the present study, we show that depletion of acyl-CoA-binding protein, Acb1p, in yeast affects ceramide levels, protein trafficking, vacuole fusion and structure. Vacuoles in Acb1p-depleted cells a ...
|
| Repository |
Bibliotheque Numerique RERO DOC
Repository Info
|
| Language |
English
|
|
View document details...
|
