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Neither leucine nor rapamycin had any effect on the activation of the upstream mTORC1 regulators, AMP-activated protein kinase and protein kinase B, in skeletal muscle or liver. The activation of eIF2α and elongation factor 2 was not affected by leucine or rapamycin, indicating that these two pathways are not limiting steps of leucine-induced protein synthesis. 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Das Förderungsinstrumentarium sollte dahingehend ergänzt werden, daß es eine Erhöhung der Transparenz von Investitionschancen ebenso einschließt wie die Anregung von Forschungsaktivitäten, die die Unternehmen mit dem Ziel betreiben, für die Verhältnisse in Entwicklungsländern geeignete Produktionstechniken hervorzubringen.\"],\"language\":\"deu/ger\",\"subjects\":[\"ddc:330\"],\"creators\":[\"Agarwal, Jamuna Prasad\"],\"publicationdate\":\"1972-01-01\",\"publisher\":\"Kiel Institute for the World Economy (IfW) Kiel\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"EconStor\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10419/47961\",\"license\":\"OPEN\",\"hostedby\":\"EconStor\",\"instancetype\":\"Research\"},{\"url\":\"http://econstor.eu/bitstream/10419/47961/1/41172049X.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://econstor.eu/bitstream/10419/47961/1/41172049X.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}]},\"provenance\":{\"repositoryName\":\"Research Papers in Economics\",\"url\":\"http://econstor.eu/bitstream/10419/47961/1/41172049X.pdf\",\"id\":\"oai:RePEc:zbw:ifwkdp:17\"},\"trust\":0.36322844}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"EconStor"},"target_publication_id":{"type":"STRING","value":"oai:econstor.eu:10419/47961"},"target_publication_author_list":{"type":"LIST_STRING","value":["Agarwal, Jamuna Prasad"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:RePEc:zbw:ifwkdp:17"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"},"target_publication_subject_list":{"type":"LIST_STRING","value":["ddc:330"]},"trust":{"type":"FLOAT","value":0.36322844},"target_publication_title":{"type":"STRING","value":"Direktinvestitionen in Entwicklungsländern und die deutsche Förderungspolitik"},"provenance_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_dateofacceptance":{"type":"DATE","value":"1972-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::7fea637fd6d02b8f0adf6f7dc36aed93"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:zbw:ifwkdp:17\",\"titles\":[\"Direktinvestitionen in Entwicklungsländern und die deutsche Förderungspolitik\"],\"abstracts\":[\"Direktinvestitionen fördern die Kapitalbildung in Entwicklungsländern, vermitteln betriebswirtschaftliches Können und übertragen technologisches „know-how\\\". Aus diesem Grunde haben seit den fünfziger Jahren Entwicklungs- und Industrieländer Direktinvestitionen verschiedenartig gefördert. Wie die Erfahrungen lehren, tragen Direktinvestitionen dazu bei, in Entwicklungsländern Zahlungsbilanzschwierigkeiten zu vergrößern, interregionale Ungleichgewichte zu verschärfen und heimische Unternehmen vom Kapital- und Arbeitsmarkt zu verdrängen. , Das Unbehagen über diese Entwicklung hat in letzter Zeit in der BRD (aber nicht nur hier) die Kritik an der deutschen Förderungspolitik zunehmen lassen. Solange Unternehmer öffentliche Mittel zur Durchführung ihrer Investitionen in Entwicklungsländern in Anspruch nehmen, muß ihnen die Bundesregierung Bedingungen stellen können, die gewährleisten, daß die von ihr festgelegten Entwicklungsziele nicht gefährdet werden. Dazu bedarf es allerdings einer Reform der gegenwärtigen Förderungspolitik. Eine solche Reform erscheint auch deshalb angebracht, weil die Förderungsmittel knapp sind und sie in vielen Fällen für die Investitionen in Ländern und Branchen verwendet werden, in denen diese Investitionen auch ohne eine öffentliche Unterstützung getätigt worden wären. Zu erwägen ist, nur solche Investitionen zu fördern, die (1) den tatsächlichen und potentiellen komparativen Vorteilen der Entwicklungsländer gerecht werden, (2) eine Exportorientierung der Unternehmen weder verbieten noch einschränken, und (3) auch den am weitesten zurückliegenden Entwicklungsländern zugute kommen. Das Förderungsinstrumentarium sollte dahingehend ergänzt werden, daß es eine Erhöhung der Transparenz von Investitionschancen ebenso einschließt wie die Anregung von Forschungsaktivitäten, die die Unternehmen mit dem Ziel betreiben, für die Verhältnisse in Entwicklungsländern geeignete Produktionstechniken hervorzubringen.\"],\"language\":\"und\",\"subjects\":[],\"creators\":[\"Agarwal, Jamuna Prasad\"],\"publicationdate\":\"1972-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Research Papers in Economics\"],\"pids\":[],\"instances\":[{\"url\":\"http://econstor.eu/bitstream/10419/47961/1/41172049X.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"},{\"url\":\"http://hdl.handle.net/10419/47961\",\"license\":\"OPEN\",\"hostedby\":\"EconStor\",\"instancetype\":\"Research\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10419/47961\",\"license\":\"OPEN\",\"hostedby\":\"EconStor\",\"instancetype\":\"Research\"}]},\"provenance\":{\"repositoryName\":\"EconStor\",\"url\":\"http://hdl.handle.net/10419/47961\",\"id\":\"oai:econstor.eu:10419/47961\"},\"trust\":0.24500424}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_publication_id":{"type":"STRING","value":"oai:RePEc:zbw:ifwkdp:17"},"target_publication_author_list":{"type":"LIST_STRING","value":["Agarwal, Jamuna Prasad"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:econstor.eu:10419/47961"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::7fea637fd6d02b8f0adf6f7dc36aed93"},"trust":{"type":"FLOAT","value":0.24500424},"target_publication_title":{"type":"STRING","value":"Direktinvestitionen in Entwicklungsländern und die deutsche Förderungspolitik"},"provenance_datasource_name":{"type":"STRING","value":"EconStor"},"target_dateofacceptance":{"type":"DATE","value":"1972-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2978793\",\"titles\":[\"Breeding Services and the Factors Influencing Their Use on Smallholder Dairy Farms in Central Uganda\"],\"abstracts\":[\"Dairy cattle breeding is an important technology in the enhancement and promotion of dairy production in Uganda. The introduction of germplasm through AI is crucial to enhance the production potential of the local breeds. A study was conducted in six districts of Uganda in the central region using a questionnaire survey involving 450 randomly selected households to profile the dairy breeding services in use and investigate the factors that affect the success of dairy breeding focusing on AI. Adoption of the AI service was highly (P \\u003c 0.05) dependent on ava ilability of extension services, record keeping practice (P \\u003c 0.05), and availability of milk markets (P \\u003c 0.05). On the other hand AI adoption was independent of formal education, age of farmer, labor availability, and feed/water availability (P \\u003e 0.05). Use or nonuse of AI did not significantly (P \\u003e 0.05) influence the sex of the calf born. While preference for AI was marked, very few farmers actually used it. This implies that focus should be put on improved AI service delivery alongside improved extension services.\"],\"language\":\"eng\",\"subjects\":[\"Research Article\"],\"creators\":[\"Mugisha, Anthony\",\"Kayiizi, Vincent\",\"Owiny, David\",\"Mburu, John\"],\"publicationdate\":\"2014-03-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Veterinary Medicine International\",\"issn\":\"2090-8113\",\"eissn\":\"2042-0048\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2014/169380\",\"type\":\"doi\"},{\"value\":\"PMC3977118\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3977118\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2014/169380\",\"license\":\"OPEN\",\"hostedby\":\"Veterinary Medicine International\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2014/169380\",\"license\":\"OPEN\",\"hostedby\":\"Veterinary Medicine International\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2014/169380\",\"id\":\"oai:doaj.org/article:9885b7be09bf4809976261d49e70d8e7\"},\"trust\":0.7522113}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2978793"},"target_publication_author_list":{"type":"LIST_STRING","value":["Mugisha, Anthony","Kayiizi, Vincent","Owiny, David","Mburu, John"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:9885b7be09bf4809976261d49e70d8e7"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research Article"]},"trust":{"type":"FLOAT","value":0.7522113},"target_publication_title":{"type":"STRING","value":"Breeding Services and the Factors Influencing Their Use on Smallholder Dairy Farms in Central Uganda"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2014-03-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2881288\",\"titles\":[\"Applications of Delayed Fluorescence from Photosystem II\"],\"abstracts\":[\"While photosystem II (PSII) of plants utilizes light for photosynthesis, part of the absorbed energy may be reverted back and dissipated as long-term fluorescence (delayed fluorescence or DF). Because the generation of DF is coupled with the processes of forward photosynthetic activities, DF contains the information about plant physiological states and plant-environment interactions. This makes DF a potentially powerful biosensing mechanism to measure plant photosynthetic activities and environmental conditions. While DF has attracted the interest of many researchers, some aspects of it are still unknown because of the complexity of photosynthetic system. In order to provide a holistic picture about the usefulness of DF, it is meaningful to summarize the research on DF applications. In this short review, available literature on applications of DF from PSII is summarized.\"],\"language\":\"eng\",\"subjects\":[\"Review\",\"delayed fluorescence\",\"delayed light\",\"delayed luminescence\",\"chlorophyll fluorescence\",\"plant stress\",\"environmental pollution\",\"photosynthesis\"],\"creators\":[\"Guo, Ya\",\"Tan, Jinglu\"],\"publicationdate\":\"2013-12-01\",\"publisher\":\"Molecular Diversity Preservation International (MDPI)\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Sensors (Basel, Switzerland)\",\"issn\":\"\",\"eissn\":\"1424-8220\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3390/s131217332\",\"type\":\"doi\"},{\"value\":\"PMC3892870\",\"type\":\"pmc\"},{\"value\":\"24351639\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3892870\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.mdpi.com/1424-8220/13/12/17332\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.mdpi.com/1424-8220/13/12/17332\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.mdpi.com/1424-8220/13/12/17332\",\"id\":\"oai:doaj.org/article:a5a576b83ab945038eed532ebd8272c7\"},\"trust\":0.10123026}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2881288"},"target_publication_author_list":{"type":"LIST_STRING","value":["Guo, Ya","Tan, Jinglu"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:a5a576b83ab945038eed532ebd8272c7"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Review","delayed fluorescence","delayed light","delayed luminescence","chlorophyll fluorescence","plant stress","environmental pollution","photosynthesis"]},"trust":{"type":"FLOAT","value":0.10123026},"target_publication_title":{"type":"STRING","value":"Applications of Delayed Fluorescence from Photosystem II"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2013-12-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:pra:mprapa:26377\",\"titles\":[\"Urban Cooperative Banks: A Case Study of Karnataka\"],\"abstracts\":[\"The Urban Cooperative Banks catering to the needs of the people of the weaker sections in the urban areas are a powerful means of financial empowerment and financial inclusion. 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Based on the products that could be matched between these countries, the estimated manufacturing production PPPs for China, Japan and Korea are only from half to two thirds of the prevailing market exchange rates, suggesting much lower cost of production in manufacturing in these countries than in the US. The estimated PPPs are used to calculate industry-level output and labour productivity in China, Japan and Korea relative to those of the US in circa 1935. The results show that the size of factory manufacturing in Japan was 12 percent of the US level whereas in China it was only one percent and even lower in Korea. 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Red foxes are\\n the main reservoir of rabies in Slovenia. When the oral vaccination program\\n had started on the whole territory of Slovenia in the year 1995, 1089\\n (28.75%) of tested animals were detected positive among wild and domestic\\n animals. Four years later only 6 (0.5%) positive cases were detected among\\n 1195 tested animals. The number of positive cases has been increasing again\\n in 2001 to 135 cases. Between 2002 and 2008 the vaccination was been done\\n only in the protection zone, i.e. 30 to 50 km wide belt along southern border\\n with Croatia because no new rabies cases were found in the north-west region\\n of Slovenia. When rabies was reintroduced in Italy in 2008 the vaccination is\\n carried out again on the whole territory of Slovenia. To improve the\\n vaccination campaign the stability of two vaccines was measured over 8 weeks.\\n In both vaccines the drop of the virus titre was highest when baits were\\n placed on sunlight, but in the shadow the virus was detected until 53 days of\\n observation. The aim of this study is to summarise the current rabies status\\n and to look for the best solutions in the vaccination campaign to come.\"],\"language\":\"und\",\"subjects\":[\"control\",\"oral vaccination\",\"rabies\"],\"creators\":[\"Hostnik P.\",\"Rihtarič Danijela\",\"Grom J.\",\"Malovrh T.\",\"Toplak I.\"],\"publicationdate\":\"2011-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"National Library of Serbia - Digital Object Identifier Repository\"],\"pids\":[{\"value\":\"10.2298/AVB1103163H\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://dx.doi.org/10.2298/AVB1103163H\",\"license\":\"OPEN\",\"hostedby\":\"National Library of Serbia - Digital Object Identifier Repository\",\"instancetype\":\"Unknown\"},{\"url\":\"http://www.doiserbia.nb.rs/img/doi/0567-8315/2011/0567-83151103163H.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Acta Veterinaria\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.doiserbia.nb.rs/img/doi/0567-8315/2011/0567-83151103163H.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Acta Veterinaria\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.doiserbia.nb.rs/img/doi/0567-8315/2011/0567-83151103163H.pdf\",\"id\":\"oai:doaj.org/article:a5248b643407491787cf3fd233482e79\"},\"trust\":0.5104773}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"National Library of Serbia - Digital Object Identifier Repository"},"target_publication_id":{"type":"STRING","value":"oai:doiserbia:0567-83151103163H"},"target_publication_author_list":{"type":"LIST_STRING","value":["Hostnik P.","Rihtarič Danijela","Grom J.","Malovrh T.","Toplak I."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:a5248b643407491787cf3fd233482e79"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["control","oral vaccination","rabies"]},"trust":{"type":"FLOAT","value":0.5104773},"target_publication_title":{"type":"STRING","value":"Maintenance and control of the vaccination belt along neighbouring rabies infected area"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2011-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::1aa48fc4880bb0c9b8a3bf979d3b917e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:ub.rug.nl:dbi/4e0b30de88106\",\"titles\":[\"Eiwitsynthese in een celvrij leversysteem\"],\"abstracts\":[\"INLEIDING\\nDe genetische informatie wordt van het DNA naar het eiwit overgedragen door een speciaal ribonuclefnezuur, messenger-RNA genaamd. Deze voorstelling is algemeen aanvaard.\\nDe messenger is ontdekt bij het onderzoek over de vermenigvuldiging van een bacteriofaag in een bacterie. Daarna is het bestaan van messengers ook in niet-geinfecteerde bacterien aannemelijk gemaakt. Men moet redelijkerwijs aannemen oat het proces van de eiwitsynthese bij dierlijke organismen niet fundamenteel anders zal zijn. Directe bewlJzen voor het bestaan van messengers in dierlijke organismen zijn er echter niet. Er bestaat geen methode messengers in vitro op hun functionele activiteit te testen en daarmee hun hoeveelheid te bepalen. Dit is ook de grote handicap bij het onderzoek naar de regulering van de eiwitsynthese. De regulering zal of op de hoeveelheid of op de vertaling van de messenger aangrijpen.\\nHet doel van ons onderzoek was een systeem te ontwikkelen waarin RNA \\u0027s van hogere organismen op hun messengeractiviteit konden worden getest. Toen wij met ons onderzoek begonnen was er al een analoog systeem uit Escherichia coli in gebruik. Slechts in een geval -met het RNA van een bacteriofaag als messenger -was bewezen dat het systeem bruikbaar was.\\nDaar het niet zeker was, en nog steeds niet zeker is, of messengers van hogere organismen weI in dit bacteriele systeem kunnen werken, leek het ons zinvol om te onderzoeken of er een dergelijk systeem uit een dierlijk organisme was te isoleren. We kozen daarvoor een orgaan met een hoge eiwitsynthese, namelijk (ratte)lever. Onze eerdere pogingen met pancreas waren mislukt tengevolge van het hoge gehalte aan ribonuclease en andere hydrolytische enzymen van dit orgaan.\\nIn het eerste hoofdstuk zal de huidige kennis van het mechanisme van de eiwitsynthese worden besproken. 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This is especially true for infections caused by Pseudomonas aeruginosa, an opportunistic pathogen with the ability to rapidly develop resistance to multiple classes of antibiotics. Objectives This study was conducted to determine the prevalence of metallo-β-lactamase (MBL)–producing strains among multidrug-resistant P. aeruginosa strains isolated from burn patients. Materials and Methods The isolates were identified, tested for susceptibility to various antimicrobial agents, and screened for the presence of MβLs by using the double-disk synergy test. The minimal inhibitory concentration of imipenem was determined by microplate broth dilution method on Mueller-Hinton agar. To detect VIM, SIM, and GIM MBLs, the isolates were subjected to polymerase chain reaction. Results In this study, we identified 100 P. aeruginosa isolates from 176 clinical specimens obtained from burn patients. The isolates showed maximum resistance to ampicillin (100%), ceftazidime (94%), and ceftriaxone (89%). The CLSI-MBL phenotypic test showed that of the 100 P. aeruginosa isolates, 22 (22%) were positive for MBL production in the double-disk synergy test. Of the 22 MBL-positive P. aeruginosa isolates, 8 were resistant to imipenem. PCR analysis showed that 8 isolates were positive for blaVIM1. The other genes blaSIM1 and blaGIM1 were not detected. Conclusions The study results demonstrate the serious therapeutic threat of the spread of MBL producers among P. aeruginosa populations. Metallo-β-lactamases were detected in 22% of imipenem-resistant P. aeruginosa isolates. Early detection and infection-control practices are the best antimicrobial strategies for this organism; therefore, systematic surveillance to detect MBL producers is necessary.\"],\"language\":\"eng\",\"subjects\":[\"Original Article\",\"Burn Patients\",\"P. aeruginosa\",\"Metallo-β-lactamase\",\"Imipenem Resistance\"],\"creators\":[\"Kalantar, Enayatollah\",\"Torabi, Vahideh\",\"Salimizand, Heiman\",\"Soheili, Fariborz\",\"Beiranvand, Soheila\",\"Soltan Dallal, Mohammad Mehdi\"],\"publicationdate\":\"2012-01-01\",\"publisher\":\"DocS\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Jundishapur Journal of Natural Pharmaceutical Products\",\"issn\":\"1735-7780\",\"eissn\":\"2228-7876\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"PMC3941862\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3941862\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://jjnpp.com/?page\\u003darticle\\u0026article_id\\u003d3546\",\"license\":\"OPEN\",\"hostedby\":\"Jundishapur Journal of Natural Pharmaceutical Products\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://jjnpp.com/?page\\u003darticle\\u0026article_id\\u003d3546\",\"license\":\"OPEN\",\"hostedby\":\"Jundishapur Journal of Natural Pharmaceutical Products\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://jjnpp.com/?page\\u003darticle\\u0026article_id\\u003d3546\",\"id\":\"oai:doaj.org/article:56f126b36c014b43bb4f6930256c313e\"},\"trust\":0.07556015}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2932464"},"target_publication_author_list":{"type":"LIST_STRING","value":["Kalantar, Enayatollah","Torabi, Vahideh","Salimizand, Heiman","Soheili, Fariborz","Beiranvand, Soheila","Soltan Dallal, Mohammad Mehdi"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:56f126b36c014b43bb4f6930256c313e"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Original Article","Burn Patients","P. aeruginosa","Metallo-β-lactamase","Imipenem Resistance"]},"trust":{"type":"FLOAT","value":0.07556015},"target_publication_title":{"type":"STRING","value":"First Survey of Metallo-β–Lactamase Producers in Clinical Isolates of Pseudomonas aeruginosa From a Referral Burn Center in Kurdistan Province"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2012-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2316474\",\"titles\":[\"Pleural Fluid Analysis: Standstill or a Work in Progress?\"],\"abstracts\":[\"Pleural fluid analysis yields important diagnostic information in pleural effusions in combination with clinical history, examination, and radiology. For more than 30 years, the initial and most pragmatic step in this process is to determine whether the fluid is a transudate or an exudate. Light\\u0027s criteria remain the most robust in separating the transudate-exudate classification which dictates further investigations or management. Recent studies have led to the evaluation and implementation of a number of additional fluid analyses that may improve the diagnostic utility of this method. This paper discusses the current practice and future direction of pleural fluid analysis in determining the aetiology of a pleural effusion. While this has been performed for a few decades, a number of other pleural characteristics are becoming available suggesting that this diagnostic tool is indeed a work in progress.\"],\"language\":\"eng\",\"subjects\":[\"Review Article\"],\"creators\":[\"Hassan, T.\",\"Al-Alawi, M.\",\"Chotirmall, S. H.\",\"Mcelvaney, N. 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Clarification of constituent BCTs will promote easy and reliable application of the interventions in clinical settings and research. Methods A published taxonomy of BCTs was used to code two interventions (group and individual) to increase adherence to eye drops. Intervention materials were coded by assigning a BCT label to each text unit. We noted the frequency with which each BCT occurred, compared the interventions in terms of the BCTs that were delivered, and identified whether the taxonomy was sufficient to describe the intervention components. Results The individual intervention consisted of 94 text units. Fifty-seven were identified as targeting behavior change and coded using 18 BCTs, many coded more than once. In the group intervention, 165 units of text were identified, and 125 were coded using 22 BCTs. The most frequently coded BCT was “provide information about behavior–health link” in the group intervention and “prompt barrier identification” in the individual intervention. The interventions included similar BCTs. All text units targeting behavior change were codable into BCTs. Conclusion The similarity of the two interventions may have implications for the cost-effectiveness of the interventions. The taxonomy was found sufficient to describe both interventions. 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Pascale\\\"\",\"Fondazione Melanoma Onlus Via Mariano Semmola ; Fondazione Melanoma Onlus Via Mariano Semmola\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1186/1479-5876-10-1\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://www.hal.inserm.fr/inserm-00664981\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://www.hal.inserm.fr/inserm-00664981\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.hal.inserm.fr/inserm-00664981\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://www.hal.inserm.fr/inserm-00664981\",\"id\":\"oai:www.hal.inserm.fr:inserm-00664981\"},\"trust\":0.62584186}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:inserm-00664981v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Galon, Jérôme","Pagès, Franck","Marincola, Francesco","Thurin, Magdalena","Trinchieri, Giorgio","Fox, Bernard","Gajewski, Thomas","Ascierto, Paolo"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:www.hal.inserm.fr:inserm-00664981"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[SDV.MHEP] Life Sciences/Human health and pathology","[SDV.IMM] Life Sciences/Immunology"]},"trust":{"type":"FLOAT","value":0.62584186},"target_publication_title":{"type":"STRING","value":"The immune score as a new possible approach for the classification of cancer."},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2012-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:www.tara.tcd.ie:2262/44904\",\"titles\":[\"Functional definition of the tobacco protoporphyrinogen IX oxidase substrate-binding site\"],\"abstracts\":[\"Abstract\\n PPO (protoporphyrinogen IX oxidase) catalyses the flavi-dependent six-electron oxidation of protogen (protoporphyrinogen IX) to form proto (protoporphyrin IX), a crucial step in heme and chlorophyll biosynthesis. The apparent K m} value for wildtype tobacco PPO2 (mitochondrial PPO) was 1.17 microM, with a v max} of 4.27 microM min -1}mg -1} and a catalytic activity k cat} of 6.0 s -1}. Amino acid residues that appear important for substrate binding in a crystal structure based model of the substrate docked in the active site were interrogated by site-directed mutagenesis. PPO2 variant F392H did not reveal detectable enzyme activity indicating an important role of Phe 392} in substrate ring A stacking. Mutations of Leu 356}, Leu 372} and Arg 98} increased k cat} values up to 100-fold indicating that the native residues are not essential for establishing an orientation of the substrate conducive to catalysis. Increased K m} values of these PPO2 variants from 2 - 100-fold suggest that these residues are involved but not essential to substrate binding via ring B and C. Moreover, one prominent structural constellation of human PPO causing the disease variegate porphyria (N67W/S374D) was successfully transferred into the tobacco PPO2 background. Therefore, tobacco PPO2 represents a useful model system for the understanding of the structure-function relationship underlying detrimental human enzyme defects.\"],\"language\":\"eng\",\"subjects\":[\"Life Sciences\"],\"creators\":[],\"publicationdate\":\"2006-11-30\",\"publisher\":\"Portland Press Limited\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Trinity\\u0027s Access to Research Archive\"],\"pids\":[{\"value\":\"10.1042/BJ20061321\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://hdl.handle.net/2262/44904\",\"license\":\"OPEN\",\"hostedby\":\"Trinity\\u0027s Access to Research Archive\",\"instancetype\":\"\"},{\"url\":\"https://hal.archives-ouvertes.fr/hal-00478655\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00478655\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.archives-ouvertes.fr/hal-00478655\",\"id\":\"oai:HAL:hal-00478655v1\"},\"trust\":0.2773159}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Trinity\u0027s Access to Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:www.tara.tcd.ie:2262/44904"},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:hal-00478655v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Life Sciences"]},"trust":{"type":"FLOAT","value":0.2773159},"target_publication_title":{"type":"STRING","value":"Functional definition of the tobacco protoporphyrinogen IX oxidase substrate-binding site"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2006-11-30"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::210f760a89db30aa72ca258a3483cc7f"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:hal-00478655v1\",\"titles\":[\"Functional definition of the tobacco protoporphyrinogen IX oxidase substrate-binding site\"],\"abstracts\":[\"International audience\",\"PPO (protoporphyrinogen IX oxidase) catalyses the flavi-dependent six-electron oxidation of protogen (protoporphyrinogen IX) to form proto (protoporphyrin IX), a crucial step in heme and chlorophyll biosynthesis. The apparent K m} value for wildtype tobacco PPO2 (mitochondrial PPO) was 1.17 microM, with a v max} of 4.27 microM min -1}mg -1} and a catalytic activity k cat} of 6.0 s -1}. Amino acid residues that appear important for substrate binding in a crystal structure based model of the substrate docked in the active site were interrogated by site-directed mutagenesis. PPO2 variant F392H did not reveal detectable enzyme activity indicating an important role of Phe 392} in substrate ring A stacking. Mutations of Leu 356}, Leu 372} and Arg 98} increased k cat} values up to 100-fold indicating that the native residues are not essential for establishing an orientation of the substrate conducive to catalysis. Increased K m} values of these PPO2 variants from 2 - 100-fold suggest that these residues are involved but not essential to substrate binding via ring B and C. Moreover, one prominent structural constellation of human PPO causing the disease variegate porphyria (N67W/S374D) was successfully transferred into the tobacco PPO2 background. Therefore, tobacco PPO2 represents a useful model system for the understanding of the structure-function relationship underlying detrimental human enzyme defects.\"],\"language\":\"eng\",\"subjects\":[\"Life Sciences\"],\"creators\":[\"Heinemann, Ilka U.\",\"Diekmann, Nina\",\"Masoumi, Ava\",\"Koch, Michael\",\"Messerschmidt, Albrecht\",\"Jahn, Martina\",\"Jahn, Dieter\"],\"publicationdate\":\"2006-11-30\",\"publisher\":\"Portland Press\",\"embargoenddate\":\"\",\"contributor\":[\"Technical University of Braunschweig ; Institute of Microbiology\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1042/BJ20061321\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00478655\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://hdl.handle.net/2262/44904\",\"license\":\"OPEN\",\"hostedby\":\"Trinity\\u0027s Access to Research Archive\",\"instancetype\":\"\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/2262/44904\",\"license\":\"OPEN\",\"hostedby\":\"Trinity\\u0027s Access to Research Archive\",\"instancetype\":\"\"}]},\"provenance\":{\"repositoryName\":\"Trinity\\u0027s Access to Research Archive\",\"url\":\"http://hdl.handle.net/2262/44904\",\"id\":\"oai:www.tara.tcd.ie:2262/44904\"},\"trust\":0.38080198}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:hal-00478655v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Heinemann, Ilka U.","Diekmann, Nina","Masoumi, Ava","Koch, Michael","Messerschmidt, Albrecht","Jahn, Martina","Jahn, Dieter"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:www.tara.tcd.ie:2262/44904"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::210f760a89db30aa72ca258a3483cc7f"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Life Sciences"]},"trust":{"type":"FLOAT","value":0.38080198},"target_publication_title":{"type":"STRING","value":"Functional definition of the tobacco protoporphyrinogen IX oxidase substrate-binding site"},"provenance_datasource_name":{"type":"STRING","value":"Trinity\u0027s Access to Research Archive"},"target_dateofacceptance":{"type":"DATE","value":"2006-11-30"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:wwu.de:a2a9a9ad-b9dc-4fdb-ad35-b75e78a90302\",\"titles\":[\"Low-level jets and above-canopy drainage as causes of turbulent exchange in the nocturnal boundary layer\"],\"abstracts\":[\"Sodar (SOund Detection And Ranging), eddy-covariance, and tower profile measurements of wind speed and carbon dioxide were performed during 17 consecutive nights in complex terrain in northern Taiwan. The scope of the study was to identify the causes for intermittent turbulence events and to analyze their importance in nocturnal atmosphere–biosphere exchange as quantified with eddy-covariance measurements. If intermittency occurs frequently at a measurement site, then this process needs to be quantified in order to achieve reliable values for ecosystem characteristics such as net ecosystem exchange or net primary production. Fourteen events of intermittent turbulence were identified and classified into above-canopy drainage flows (ACDFs) and low-level jets (LLJs) according to the height of the wind speed maximum. Intermittent turbulence periods lasted between 30 and 110 min. Towards the end of LLJ or ACDF events, positive vertical wind velocities and, in some cases, upslope flows occurred, counteracting the general flow regime at nighttime. The observations suggest that the LLJs and ACDFs penetrate deep into the cold air pool in the valley, where they experience strong buoyancy due to density differences, resulting in either upslope flows or upward vertical winds. Turbulence was found to be stronger and better developed during LLJs and ACDFs, with eddy-covariance data presenting higher quality. This was particularly indicated by spectral analysis of the vertical wind velocity and the steady-state test for the time series of the vertical wind velocity in combination with the horizontal wind component, the temperature, and carbon dioxide. Significantly higher fluxes of sensible heat, latent heat, and shear stress occurred during these periods. During LLJs and ACDFs, fluxes of sensible heat, latent heat, and CO2 were mostly one-directional. For example, exclusively negative sensible heat fluxes occurred while intermittent turbulence was present. Latent heat fluxes were mostly positive during LLJs and ACDFs, with a median value of 34 W m−2, while outside these periods the median was 2 W m−2. In conclusion, intermittent turbulence periods exhibit a strong impact on nocturnal energy and mass fluxes.\\u003cbr\\u003e\"],\"language\":\"eng\",\"subjects\":[\"ddc:550\",\"info:eu-repo/classification/ddc/550\",\"Earth sciences\"],\"creators\":[\"El-Madany, T. S.\",\"Duarte, H. F.\",\"Durden, D. J.\",\"Paas, B.\",\"Deventer, M. J.\",\"Juang, J.\",\"Leclerc, M. Y.\",\"Klemm, O.\"],\"publicationdate\":\"2014-10-31\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[\"Universitäts- und Landesbibliothek Münster\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Münstersches Informations und Archivsystem für Multimediale Inhalte\"],\"pids\":[{\"value\":\"10.5194/bg-11-4507-2014\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"https://nbn-resolving.org/urn:nbn:de:hbz:6-01369464830\",\"license\":\"OPEN\",\"hostedby\":\"Münstersches Informations und Archivsystem für Multimediale Inhalte\",\"instancetype\":\"Article\"},{\"url\":\"http://www.biogeosciences.net/11/4507/2014/bg-11-4507-2014.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Biogeosciences\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.biogeosciences.net/11/4507/2014/bg-11-4507-2014.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Biogeosciences\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.biogeosciences.net/11/4507/2014/bg-11-4507-2014.pdf\",\"id\":\"oai:doaj.org/article:2756f0f7394b4fef92b7fc0da6c8baa8\"},\"trust\":0.9392855}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Münstersches Informations und Archivsystem für Multimediale Inhalte"},"target_publication_id":{"type":"STRING","value":"oai:wwu.de:a2a9a9ad-b9dc-4fdb-ad35-b75e78a90302"},"target_publication_author_list":{"type":"LIST_STRING","value":["El-Madany, T. 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The prognosis of Heart Failure (HF) is uniformly poor despite advances in treatment. The aims of the present study were to determine the causes of HF among patients admitted to a Nigerian tertiary medical centre, to determine the prevalence of factors known to be associated with poor prognosis among these patients, and to compare the factors and causes between males and females. Methods The study was cross-sectional in design, carried out on eligible patients who were consecutively admitted with HF, in Aminu Kano Teaching Hospital, Kano, Nigeria. The following established factors associated with poor prognosis of HF were assessed: low Left Ventricular Ejection Fraction (LVEF) of ≤ 40%, anaemia, renal impairment, cardiac rhythm disturbances on the electrocardiogram, prolonged corrected QT interval (QTc), complete Left Bundle Branch Block (LBBB) and advanced age. Results A total of 79 patients were studied over a six-month period. Forty four (55.7%) of these patients were males while the remaining 35 (44.3%) were females. The most prevalent prognostic factor was low LVEF found in a total of 35 patients (44.3%), while the least prevalent was complete LBBB found in two male patients only (2.53%). The commonest cause of heart failure in all patients and males was hypertensive heart disease, found in a total of 45 patients (57.0%), comprising of 33 male (73.3%) and 12 female patients (26.7%) (p \\u003d 0.0003). Cardiomyopathies were the commonest causes in females, the predominant type being peripartum cardiomyopathy found in 11 (31.4%) female patients. Acute myocardial infarction has emerged to be an important cause of HF in males (13.6%) with a high in-hospital mortality of 66.7%. Conclusion The most prevalent factor associated with poor prognosis was low LVEF. Hypertensive heart disease and cardiomyopathies were the most common causes of HF in males and females respectively. The findings of the study should guide decision-making regarding management of HF patients.\"],\"language\":\"eng\",\"subjects\":[\"Research Article\"],\"creators\":[\"Karaye, Kamilu M.\",\"Sani, Mahmoud U.\"],\"publicationdate\":\"2008-07-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"BMC Cardiovascular Disorders\",\"issn\":\"\",\"eissn\":\"1471-2261\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1471-2261-8-16\",\"type\":\"doi\"},{\"value\":\"PMC2492836\",\"type\":\"pmc\"},{\"value\":\"18644161\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC2492836\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.biomedcentral.com/1471-2261/8/16\",\"license\":\"OPEN\",\"hostedby\":\"BMC Cardiovascular 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Substantial external investment, together with the requirement for service evolution to adapt to changing needs, including the constant shift to earlier ART initiation, makes outcome monitoring and reporting particularly important. However, there is growing concern at the inability of many high-burden countries to report on the outcomes of patients who have been in care for various durations, or even the number of patients in care at a particular point in time. In many instances, countries can only report on the number of patients ever started on ART. Despite paper register systems coming under increasing strain, the evolution from paper directly to complex electronic medical record solutions is not viable in many contexts. Implementing a bridging solution, such as a simple offline electronic version of the paper register, can be a pragmatic alternative. 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Le premier concerne le statut des eaux des passages arctiques, passage du Nord-ouest et du Nord-est, eaux que la Russie et le Canada considèrent comme intérieures pour leur passage respectif ; une position que contestent tant les États-Unis que l\\u0027Union européenne. Le second débat concerne la définition des frontières des espaces maritimes arctiques, zones économiques exclusives (ZEE) et surtout plateaux continentaux élargis, espaces maritimes prévus à l\\u0027article 76 de la Convention des Nations Unies sur le Droit de la mer. Cet article se penche sur la question des frontières maritimes des revendications des plateaux continentaux élargis dans l\\u0027Arctique. Les médias relayent aujourd\\u0027hui de façon récurrente l\\u0027idée d\\u0027une course à la conquête des espaces maritimes arctiques. Cela fait plusieurs années que les pays riverains de l\\u0027Arctique préparent leurs dossiers destinés à étayer leurs arguments géologiques pour revendiquer des plateaux continentaux étendus, mais ce n\\u0027est qu\\u0027en 2007 qu\\u0027une fièvre médiatique s\\u0027est développée, accréditant l\\u0027idée d\\u0027une course effrénée, alimentée par les changements climatiques pour la conquête des ressources naturelles de la région : une représentation très exagérée et peu conforme à la réalité tant historique que juridique.\"],\"language\":\"fra/fre\",\"subjects\":[\"[SHS:SCIPO] Humanities and Social Sciences/Political science\",\"[SHS:SCIPO] Sciences de l\\u0027Homme et Société/Science politique\",\"Arctic\"],\"creators\":[\"Lasserre, Frédéric\"],\"publicationdate\":\"2010-11-22\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"http://halshs.archives-ouvertes.fr/halshs-00534394\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"https://halshs.archives-ouvertes.fr/halshs-00534394\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://halshs.archives-ouvertes.fr/halshs-00534394\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://halshs.archives-ouvertes.fr/halshs-00534394\",\"id\":\"oai:HAL:halshs-00534394v1\"},\"trust\":0.4723488}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:halshs.archives-ouvertes.fr:halshs-00534394"},"target_publication_author_list":{"type":"LIST_STRING","value":["Lasserre, Frédéric"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:halshs-00534394v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[SHS:SCIPO] Humanities and Social Sciences/Political science","[SHS:SCIPO] Sciences de l\u0027Homme et Société/Science politique","Arctic"]},"trust":{"type":"FLOAT","value":0.4723488},"target_publication_title":{"type":"STRING","value":"Plateaux continentaux et frontières maritimes dans l\u0027Arctique : la guerre froide n\u0027aura pas lieu"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2010-11-22"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:halshs-00534394v1\",\"titles\":[\"Plateaux continentaux et frontières maritimes dans l\\u0027Arctique : la guerre froide n\\u0027aura pas lieu\"],\"abstracts\":[\"Deux grandes questions politico-juridiques structurent aujourd\\u0027hui les relations des pays riverains de l\\u0027océan Arctique. Le premier concerne le statut des eaux des passages arctiques, passage du Nord-ouest et du Nord-est, eaux que la Russie et le Canada considèrent comme intérieures pour leur passage respectif ; une position que contestent tant les États-Unis que l\\u0027Union européenne. Le second débat concerne la définition des frontières des espaces maritimes arctiques, zones économiques exclusives (ZEE) et surtout plateaux continentaux élargis, espaces maritimes prévus à l\\u0027article 76 de la Convention des Nations Unies sur le Droit de la mer. Cet article se penche sur la question des frontières maritimes des revendications des plateaux continentaux élargis dans l\\u0027Arctique. Les médias relayent aujourd\\u0027hui de façon récurrente l\\u0027idée d\\u0027une course à la conquête des espaces maritimes arctiques. Cela fait plusieurs années que les pays riverains de l\\u0027Arctique préparent leurs dossiers destinés à étayer leurs arguments géologiques pour revendiquer des plateaux continentaux étendus, mais ce n\\u0027est qu\\u0027en 2007 qu\\u0027une fièvre médiatique s\\u0027est développée, accréditant l\\u0027idée d\\u0027une course effrénée, alimentée par les changements climatiques pour la conquête des ressources naturelles de la région : une représentation très exagérée et peu conforme à la réalité tant historique que juridique.\"],\"language\":\"fra/fre\",\"subjects\":[\"Arctic\",\"[SHS.SCIPO] Humanities and Social Sciences/Political science\"],\"creators\":[\"Lasserre, Frédéric\"],\"publicationdate\":\"2010-11-22\",\"publisher\":\"HAL CCSD\",\"embargoenddate\":\"\",\"contributor\":[\"Université de laval (UL) ; Universite Laval (Quebec) - Canada\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"https://halshs.archives-ouvertes.fr/halshs-00534394\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://halshs.archives-ouvertes.fr/halshs-00534394\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://halshs.archives-ouvertes.fr/halshs-00534394\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://halshs.archives-ouvertes.fr/halshs-00534394\",\"id\":\"oai:halshs.archives-ouvertes.fr:halshs-00534394\"},\"trust\":0.36241686}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:halshs-00534394v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Lasserre, Frédéric"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:halshs.archives-ouvertes.fr:halshs-00534394"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Arctic","[SHS.SCIPO] Humanities and Social Sciences/Political science"]},"trust":{"type":"FLOAT","value":0.36241686},"target_publication_title":{"type":"STRING","value":"Plateaux continentaux et frontières maritimes dans l\u0027Arctique : la guerre froide n\u0027aura pas lieu"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2010-11-22"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3383953\",\"titles\":[\"Exposure to Seasonal Temperatures during the Last Month of Gestation and the Risk of Preterm Birth in Stockholm\"],\"abstracts\":[\"Recent evidence from studies performed mainly in warm climates suggests an association between exposure to extreme temperatures late in pregnancy and an increased risk of preterm delivery. However, there have been fewer studies on the effect of low temperatures. The aim of this study is to explore the potential association between both heat and cold during late pregnancy and an increased risk of preterm birth in the northern location of Stockholm, Sweden. All singleton spontaneous births that took place in greater Stockholm (1998–2006) were included. Non-linear and delayed effects of mean temperature on the risk of preterm birth were explored through distributed lag non-linear models. Extreme and moderate heat and cold were estimated separately through quasi-Poisson regression analysis in two seasonal periods (heat in warm season, cold in cold season). The risk of preterm birth increased by 4%–5% when the mean temperature reached the 75th percentile (moderate heat) four weeks earlier (reference: the annual median value), with a maximum cumulative risk ratio of 2.50 (95% confidence interval: 1.02–6.15). Inconsistent associations were obtained for cold and extreme heat. Exposure to moderately high temperatures during late pregnancy might be associated with an increase in risk of preterm birth in Stockholm.\"],\"language\":\"eng\",\"subjects\":[\"Article\",\"preterm birth\",\"climate change\",\"ambient temperature\",\"heat\",\"cold\"],\"creators\":[\"Vicedo-Cabrera, Ana M.\",\"Olsson, David\",\"Forsberg, Bertil\"],\"publicationdate\":\"2015-04-01\",\"publisher\":\"MDPI\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"International Journal of Environmental Research and Public Health\",\"issn\":\"1661-7827\",\"eissn\":\"1660-4601\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3390/ijerph120403962\",\"type\":\"doi\"},{\"value\":\"PMC4410227\",\"type\":\"pmc\"},{\"value\":\"25867199\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4410227\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.mdpi.com/1660-4601/12/4/3962\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.mdpi.com/1660-4601/12/4/3962\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.mdpi.com/1660-4601/12/4/3962\",\"id\":\"oai:doaj.org/article:72e9982eba9948eb87558a2e762e4208\"},\"trust\":0.38077438}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3383953"},"target_publication_author_list":{"type":"LIST_STRING","value":["Vicedo-Cabrera, Ana M.","Olsson, David","Forsberg, Bertil"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:72e9982eba9948eb87558a2e762e4208"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Article","preterm birth","climate change","ambient temperature","heat","cold"]},"trust":{"type":"FLOAT","value":0.38077438},"target_publication_title":{"type":"STRING","value":"Exposure to Seasonal Temperatures during the Last Month of Gestation and the Risk of Preterm Birth in Stockholm"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2015-04-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:arXiv.org:1006.4797\",\"titles\":[\"Modern Summation Methods and the Computation of 2- and 3-loop Feynman Diagrams\"],\"abstracts\":[\" By symbolic summation methods based on difference fields we present a general\\nstrategy that transforms definite multi-sums, e.g., in terms of hypergeometric\\nterms and harmonic sums, to indefinite nested sums and products. We succeeded\\nin this task with all our concrete calculations of 2--loop and 3--loop massive\\nsingle scale Feynman diagrams with local operator insertion.\\n\",\"Comment: 6 pages 2 figures\"],\"language\":\"eng\",\"subjects\":[\"Mathematical Physics\",\"High Energy Physics - Phenomenology\",\"High Energy Physics - Theory\"],\"creators\":[\"Ablinger, J.\",\"Blümlein, J.\",\"Klein, S.\",\"Schneider, C.\"],\"publicationdate\":\"2010-06-24\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"arXiv.org e-Print Archive\"],\"pids\":[{\"value\":\"10.1016/j.nuclphysbps.2010.08.028\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://arxiv.org/abs/1006.4797\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"},{\"url\":\"http://pubdb.desy.de/anonymous/search.php?lid\\u003d14404\",\"license\":\"OPEN\",\"hostedby\":\"DESY Publication Database\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://pubdb.desy.de/anonymous/search.php?lid\\u003d14404\",\"license\":\"OPEN\",\"hostedby\":\"DESY Publication Database\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DESY Publication Database\",\"url\":\"http://pubdb.desy.de/anonymous/search.php?lid\\u003d14404\",\"id\":\"oai:hh0024.library.desy.de:14404\"},\"trust\":0.6976751}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_publication_id":{"type":"STRING","value":"oai:arXiv.org:1006.4797"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ablinger, J.","Blümlein, J.","Klein, S.","Schneider, C."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:hh0024.library.desy.de:14404"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::b9d487a30398d42ecff55c228ed5652b"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Mathematical Physics","High Energy Physics - 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2010-04-30"},"provenance_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_dateofacceptance":{"type":"DATE","value":"2010-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::b9d487a30398d42ecff55c228ed5652b"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:repository.usu.ac.id:123456789/22756\",\"titles\":[\"Peranan Polisi Sebagai Penyidik Dalam Mencari Bukti Pada Proses Penanganan Tempat Kejadian Perkara\"],\"abstracts\":[\"Polisi sebagai penyidik dalam melakukan penyidikan terhadap suatu peristiwa yang dianggap merupakan suatu tindak pidana, harus mencari bukti yang cukup terhadap dugaan tersebut sehingga membuat terang kejadian tersebut dan dapat meneruskannya kepenuntutan sampai kepengadilan. Dalam hal pencarian bukti harus dilakukan pada tempat kejadian perkara dengan cara penanganan tempat kejadian perkara yang merupakan bagian dari tahap penyidikan sehingga penyidik dapat menentukan apakah perbuatan tersebut merupakan suatu tindak pidana atau bukan yang didasari dari hasil bukti-bukti yang didapat pada tempat kejadian perkara.\\nDalam melakukan pencarian bukti pada proses penanganan tempat kejadian perkara dilakukan penyidik berdasarkan peraturan perundang-undangan yang berlaku dan sesuai dengan prosedur yang ada, adapun tata cara penanganan tempat kejadian perkara diatur dalam surat keputusan kapolri no Pol: Skep/1205/IX/2000 tentang bujuklap, bujuknis dan bujukadministrasi tentang proses penyidikan tindak pidana. \\nAdapun yang menjadi permasalahan dalam penulisan skripsi ini adalah bagaimanakah peranan penyidik dalam melakukan penanganan tempat kejadian perkara (TKP), bagaimanakah proses pencarian bukti yang dilakukan penyidik pada saat penanganan TKP, serta bagaimanakah kendala-kendala yang dihadapi penyidik dalam melakukan penanganan TKP. Guna mengetahui hal tersebut, penulis dalam pembuatan skripsi ini menggunakan Metode penulisan dengan dua metode, yakni metode penelitian hukum normatif yang berasal dari sumber buku-buku kepustakaan yang relevan dengan permasalahan yang dibahas didalam skripsi ini dan metode penelitian empiris yang dilakukan dengan cara melakukan peninjauan kelapangan dalam hal ini objeknya adalah Polsek Percut Sei Tuan dan melakukan wawancara dengan penyidik dan penyidik pembantu yang ada di polsek tersebut.\\nBerdasarkan penelitian yang dilakukan, yang menjadi kendala bagi polisi sebagai penyidik dalam mencari bukti pada proses penanganan tempat kejadian perkara secara garis besar terbagi menjadi dua yakni kendala dari luar kepolisian (kendala eksternal) dan kendala dari dalam kepolisian (kendala internal). Dengan melakukan peyuluhan terhadap masyarakat akan pentingnya penanganan tempat kejadian perkara serta melakukan pendidikan tentang penanganan tempat kejadian perkara bagi penyidik dan memenuhi sarana dan prasarana dalam melakukan penanganan tempat kejadian perkara diharapkan akan mengurangi kendala penyidik dalam mencari bukti dan membuat terang terjadinya suatu tindak pidana.\",\"070200072\"],\"language\":\"ind\",\"subjects\":[\"Peranan Polisi\",\"Penyidik\",\"Proses Penanganan Tempat Kejadian Perkara\"],\"creators\":[\"Dirgantara, Muhammad Andi\"],\"publicationdate\":\"2011-04-13\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[\"Yunara, Edi\",\"Alwan\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"USU Repository\"],\"pids\":[],\"instances\":[{\"url\":\"http://repository.usu.ac.id/handle/123456789/22756\",\"license\":\"OPEN\",\"hostedby\":\"USU Repository\",\"instancetype\":\"Unknown\"},{\"url\":\"http://repository.usu.ac.id/handle/123456789/22756\",\"license\":\"OPEN\",\"hostedby\":\"USU Repository\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://repository.usu.ac.id/handle/123456789/22756\",\"license\":\"OPEN\",\"hostedby\":\"USU Repository\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"USU Repository\",\"url\":\"http://repository.usu.ac.id/handle/123456789/22756\",\"id\":\"oai:repository.usu.ac.id:123456789/36256\"},\"trust\":0.51463497}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"USU Repository"},"target_publication_id":{"type":"STRING","value":"oai:repository.usu.ac.id:123456789/22756"},"target_publication_author_list":{"type":"LIST_STRING","value":["Dirgantara, Muhammad Andi"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:repository.usu.ac.id:123456789/36256"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::8b5700012be65c9da25f49408d959ca0"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Peranan Polisi","Penyidik","Proses Penanganan Tempat Kejadian Perkara"]},"trust":{"type":"FLOAT","value":0.51463497},"target_publication_title":{"type":"STRING","value":"Peranan Polisi Sebagai Penyidik Dalam Mencari Bukti Pada Proses Penanganan Tempat Kejadian Perkara"},"provenance_datasource_name":{"type":"STRING","value":"USU Repository"},"target_dateofacceptance":{"type":"DATE","value":"2011-04-13"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b5700012be65c9da25f49408d959ca0"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:repository.usu.ac.id:123456789/36256\",\"titles\":[\"Peranan Polisi Sebagai Penyidik Dalam Mencari Bukti Pada Proses Penanganan Tempat Kejadian Perkara\"],\"abstracts\":[\"Polisi sebagai penyidik dalam melakukan penyidikan terhadap suatu peristiwa yang dianggap merupakan suatu tindak pidana, harus mencari bukti yang cukup terhadap dugaan tersebut sehingga membuat terang kejadian tersebut dan dapat meneruskannya kepenuntutan sampai kepengadilan. Dalam hal pencarian bukti harus dilakukan pada tempat kejadian perkara dengan cara penanganan tempat kejadian perkara yang merupakan bagian dari tahap penyidikan sehingga penyidik dapat menentukan apakah perbuatan tersebut merupakan suatu tindak pidana atau bukan yang didasari dari hasil bukti-bukti yang didapat pada tempat kejadian perkara.\\nDalam melakukan pencarian bukti pada proses penanganan tempat kejadian perkara dilakukan penyidik berdasarkan peraturan perundang-undangan yang berlaku dan sesuai dengan prosedur yang ada, adapun tata cara penanganan tempat kejadian perkara diatur dalam surat keputusan kapolri no Pol: Skep/1205/IX/2000 tentang bujuklap, bujuknis dan bujukadministrasi tentang proses penyidikan tindak pidana. \\nAdapun yang menjadi permasalahan dalam penulisan skripsi ini adalah bagaimanakah peranan penyidik dalam melakukan penanganan tempat kejadian perkara (TKP), bagaimanakah proses pencarian bukti yang dilakukan penyidik pada saat penanganan TKP, serta bagaimanakah kendala-kendala yang dihadapi penyidik dalam melakukan penanganan TKP. Guna mengetahui hal tersebut, penulis dalam pembuatan skripsi ini menggunakan Metode penulisan dengan dua metode, yakni metode penelitian hukum normatif yang berasal dari sumber buku-buku kepustakaan yang relevan dengan permasalahan yang dibahas didalam skripsi ini dan metode penelitian empiris yang dilakukan dengan cara melakukan peninjauan kelapangan dalam hal ini objeknya adalah Polsek Percut Sei Tuan dan melakukan wawancara dengan penyidik dan penyidik pembantu yang ada di polsek tersebut.\\nBerdasarkan penelitian yang dilakukan, yang menjadi kendala bagi polisi sebagai penyidik dalam mencari bukti pada proses penanganan tempat kejadian perkara secara garis besar terbagi menjadi dua yakni kendala dari luar kepolisian (kendala eksternal) dan kendala dari dalam kepolisian (kendala internal). 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These compounds, among other applications, are\\nused as adhesives in the wood agglomerate industry. In this kind of application\\nsome problems remain to be solved in order to obtain a Pine extract of\\ncommercial value. It is necessary to optimise tije extraction procedure and\\nselect a suitable method for the quantification of the tannin content of the bark.\\nIn order to study these problems, the tannin extraction from the Pine bark was\\ntested with an alkaline solution (NaOH), and with a fractionation procedure\\nbased on a sequence of an organic (ethanol) and aqueous extraction. The\\nphenolic content of each extract or fraction was evaluated by the FolinCiocalteu\\ncolorimetric assay for total phenols and two procedures using the\\nStiasny reaction: the gravimetric Stiasny method and the indirect colorimetric\\nprocedure that uses the Folin-Ciocalteu reagent to evaluate the total phenols\\npresent in the extract solution before and after it condenses with formaldehyde.\\nThe yield value when the alkaline extraction is used is substantially higher\\nthan the values obtained with organic or aqueous solutions. However, the\\nselectivity of the process is low. In fact, it was found that the alkaline extract\\nFormaldehyde Condensable Phenolic Material (FCPM) content represents 9596\\n% of the total phenols content of the extract but this fraction is only ~ 40 %\\nof the total mass of extract. So, the alkaline extract is relatively poor in\\nphenolic material, exhibiting a large variety of non-phenolic extractives. On\\nthe other end, ethanol provides a very rich phenolic extract, in which 96 % of\\ntotal phenols are condensable with formaldehyde, but exhibits a relatively low\\nextraction yield. The aqueous extract presents the lowest extraction yield with\\nlow content either in phenolic material as in FCPM, but, as most of the phenolics had already been extracted by the previous organic extraction,\\nespecially the low molecular weight fractions, this result was predictable.\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Pepino, Lina\",\"Brito, Paulo\",\"Jorge, Fernando Caldeira\",\"Costa, Rui Pereira Da\",\"Gil, Maria Helena\",\"Portugal, António\"],\"publicationdate\":\"1999-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Biblioteca Digital do IPB\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10198/1285\",\"license\":\"OPEN\",\"hostedby\":\"Biblioteca Digital do IPB\",\"instancetype\":\"Conference object\"}],\"externalReferences\":[]},\"highlight\":{\"abstracts\":[\"Bark from Pinus Pinaster is an interesting source of polyphenolic natural\\ncompounds, that can be used successful1y as total or partial replacement of\\nconventional phenolic resins. These compounds, among other applications, are\\nused as adhesives in the wood agglomerate industry. In this kind of application\\nsome problems remain to be solved in order to obtain a Pine extract of\\ncommercial value. It is necessary to optimise tije extraction procedure and\\nselect a suitable method for the quantification of the tannin content of the bark.\\nIn order to study these problems, the tannin extraction from the Pine bark was\\ntested with an alkaline solution (NaOH), and with a fractionation procedure\\nbased on a sequence of an organic (ethanol) and aqueous extraction. The\\nphenolic content of each extract or fraction was evaluated by the FolinCiocalteu\\ncolorimetric assay for total phenols and two procedures using the\\nStiasny reaction: the gravimetric Stiasny method and the indirect colorimetric\\nprocedure that uses the Folin-Ciocalteu reagent to evaluate the total phenols\\npresent in the extract solution before and after it condenses with formaldehyde.\\nThe yield value when the alkaline extraction is used is substantially higher\\nthan the values obtained with organic or aqueous solutions. However, the\\nselectivity of the process is low. In fact, it was found that the alkaline extract\\nFormaldehyde Condensable Phenolic Material (FCPM) content represents 9596\\n% of the total phenols content of the extract but this fraction is only ~ 40 %\\nof the total mass of extract. So, the alkaline extract is relatively poor in\\nphenolic material, exhibiting a large variety of non-phenolic extractives. 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The aqueous extract presents the lowest extraction yield with\\nlow content either in phenolic material as in FCPM, but, as most of the phenolics had already been extracted by the previous organic extraction,\\nespecially the low molecular weight fractions, this result was predictable.\"]},\"provenance\":{\"repositoryName\":\"Biblioteca Digital do IPB\",\"url\":\"http://hdl.handle.net/10198/1280\",\"id\":\"oai:bibliotecadigital.ipb.pt:10198/1280\"},\"trust\":0.012847185}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Biblioteca Digital do IPB"},"target_publication_id":{"type":"STRING","value":"oai:bibliotecadigital.ipb.pt:10198/1285"},"target_publication_author_list":{"type":"LIST_STRING","value":["Pepino, Lina","Brito, Paulo","Jorge, Fernando Caldeira","Costa, Rui Pereira Da","Gil, Maria Helena","Portugal, António"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:bibliotecadigital.ipb.pt:10198/1280"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::3bf55bbad370a8fcad1d09b005e278c2"},"trust":{"type":"FLOAT","value":0.012847185},"target_publication_title":{"type":"STRING","value":"Comparison of quantification methods for the condensed tannin content of extracts of Pinus pinaster bark"},"provenance_datasource_name":{"type":"STRING","value":"Biblioteca Digital do IPB"},"target_dateofacceptance":{"type":"DATE","value":"1999-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::3bf55bbad370a8fcad1d09b005e278c2"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:bibliotecadigital.ipb.pt:10198/1280\",\"titles\":[\"Comparison of quantification methods for the condensed tannin content of extracts of Pinus pinaster bark\"],\"abstracts\":[\"Bark from Pinus Pinaster is an interesting source of polyphenolic natural\\ncompounds, that can be used successful1y as total or partial replacement of\\nconventional phenolic resins. These compounds, among other applications, are\\nused as adhesives in the wood agglomerate industry. In this kind of application\\nsome problems remain to be solved in order to obtain a Pine extract of\\ncommercial value. It is necessary to optimise tije extraction procedure and\\nselect a suitable method for the quantification of the tannin content of the bark.\\nIn order to study these problems, the tannin extraction from the Pine bark was\\ntested with an alkaline solution (NaOH), and with a fractionation procedure\\nbased on a sequence of an organic (ethanol) and aqueous extraction. The\\nphenolic content of each extract or fraction was evaluated by the FolinCiocalteu\\ncolorimetric assay for total phenols and two procedures using the\\nStiasny reaction: the gravimetric Stiasny method and the indirect colorimetric\\nprocedure that uses the Folin-Ciocalteu reagent to evaluate the total phenols\\npresent in the extract solution before and after it condenses with formaldehyde.\\nThe yield value when the alkaline extraction is used is substantially higher\\nthan the values obtained with organic or aqueous solutions. However, the\\nselectivity of the process is low. In fact, it was found that the alkaline extract\\nFormaldehyde Condensable Phenolic Material (FCPM) content represents 9596\\n% of the total phenols content of the extract but this fraction is only ~ 40 %\\nof the total mass of extract. So, the alkaline extract is relatively poor in\\nphenolic material, exhibiting a large variety of non-phenolic extractives. On\\nthe other end, ethanol provides a very rich phenolic extract, in which 96 % of\\ntotal phenols are condensable with formaldehyde, but exhibits a relatively low\\nextraction yield. 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This thesis presents a method that combines physiological and economic principles in the evaluation of yield advantage. A production possibility frontier, drawn from economics literature, represents the maximum yield combinations that can be obtained from intercropping. Inter- and intra-specific competition for resources determine yield in mixed cropping. Production possibility frontiers have been derived using such a priori knowledge of the processes underlying mixed cropping, thereby facilitating economic and agronomic analyses of yield advantage. The analytical procedure used in such analyses is illustrated for various crop mixtures.The assumption underlying the derivation of a production possibility frontier is the hyperbolic relationship between yield and plant density. This assumption cannot always be made for marketable yield. 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The notion of numerical dissipation is given a rigorous meaning.\"],\"language\":\"eng\",\"subjects\":[\"[INFO:INFO_MO] Computer Science/Modeling and Simulation\",\"[INFO:INFO_MO] Informatique/Modélisation et simulation\",\"[MATH:MATH_NA] Mathematics/Numerical Analysis\",\"[MATH:MATH_NA] Mathématiques/Analyse numérique\",\"[MATH:MATH_DS] Mathematics/Dynamical Systems\",\"[MATH:MATH_DS] Mathématiques/Systèmes dynamiques\",\"[SPI:AUTO] Engineering Sciences/Automatic\",\"[SPI:AUTO] Sciences de l\\u0027ingénieur/Automatique / Robotique\"],\"creators\":[\"Greenhalgh, Scott\",\"Acary, Vincent\",\"Brogliato, Bernard\"],\"publicationdate\":\"2011-05-30\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"http://hal.inria.fr/inria-00596961\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"External research report\"},{\"url\":\"https://hal.inria.fr/inria-00596961\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.inria.fr/inria-00596961\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.inria.fr/inria-00596961\",\"id\":\"oai:HAL:inria-00596961v1\"},\"trust\":0.41985345}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:hal.inria.fr:inria-00596961"},"target_publication_author_list":{"type":"LIST_STRING","value":["Greenhalgh, Scott","Acary, Vincent","Brogliato, Bernard"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:inria-00596961v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[INFO:INFO_MO] Computer Science/Modeling and Simulation","[INFO:INFO_MO] Informatique/Modélisation et simulation","[MATH:MATH_NA] Mathematics/Numerical Analysis","[MATH:MATH_NA] Mathématiques/Analyse numérique","[MATH:MATH_DS] Mathematics/Dynamical Systems","[MATH:MATH_DS] Mathématiques/Systèmes dynamiques","[SPI:AUTO] Engineering Sciences/Automatic","[SPI:AUTO] Sciences de l\u0027ingénieur/Automatique / Robotique"]},"trust":{"type":"FLOAT","value":0.41985345},"target_publication_title":{"type":"STRING","value":"Preservation of the dissipativity properties of a class of nonsmooth dynamical systems with the (θ,γ)-algorithm"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2011-05-30"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:inria-00596961v1\",\"titles\":[\"Preservation of the dissipativity properties of a class of nonsmooth dynamical systems with the (θ,γ)-algorithm\"],\"abstracts\":[\"In this work we study the following problem: given a numerical method (an extended θ−method named the (θ,γ)-method), find the class of dissipative linear complementarity sys- tems such that their discrete-time counterpart is still dissipative, with the same storage (energy) function, supply rate (reciprocal variables), and dissipation function. Systems with continuous so- lutions, and with state jumps are studied. The notion of numerical dissipation is given a rigorous meaning.\",\"Dans ce travail, on se préoccupe du problème suivant étant donée une méthode numérique (une extension du θ−sch ́ema d ́enomm ́e (θ,γ) sch ́ema), trouver la classe de systèmes de compémentarié linéaire pour laquelle la discrétisation en temps est aussi dissipative, avec la même fonction d\\u0027énergie, le même taux d\\u0027apport d\\u0027énergie (en variables réciproques) et la même fonction de dissipation. Les systèmes avec des solutions continues et avec des sauts dans l\\u0027état sont étudiés. La notion de dissipation numérique est donnée avec une interprétation rigoureuse.\"],\"language\":\"eng\",\"subjects\":[\"[INFO.INFO-MO] Computer Science/Modeling and Simulation\",\"[MATH.MATH-NA] Mathematics/Numerical Analysis\",\"[MATH.MATH-DS] Mathematics/Dynamical Systems\",\"[SPI.AUTO] Engineering Sciences/Automatic\"],\"creators\":[\"Greenhalgh, Scott\",\"Acary, Vincent\",\"Brogliato, Bernard\"],\"publicationdate\":\"2011-05-30\",\"publisher\":\"HAL CCSD\",\"embargoenddate\":\"\",\"contributor\":[\"BIPOP (INRIA Grenoble Rhône-Alpes / LJK Laboratoire Jean Kuntzmann) ; INRIA - Laboratoire Jean Kuntzmann - Université Joseph Fourier - Grenoble I - Institut polytechnique de Grenoble (Grenoble INP) - CNRS\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"https://hal.inria.fr/inria-00596961\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://hal.inria.fr/inria-00596961\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"External research report\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hal.inria.fr/inria-00596961\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"External research report\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://hal.inria.fr/inria-00596961\",\"id\":\"oai:hal.inria.fr:inria-00596961\"},\"trust\":0.82447094}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:inria-00596961v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Greenhalgh, Scott","Acary, Vincent","Brogliato, Bernard"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:hal.inria.fr:inria-00596961"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[INFO.INFO-MO] Computer Science/Modeling and Simulation","[MATH.MATH-NA] Mathematics/Numerical Analysis","[MATH.MATH-DS] Mathematics/Dynamical Systems","[SPI.AUTO] Engineering Sciences/Automatic"]},"trust":{"type":"FLOAT","value":0.82447094},"target_publication_title":{"type":"STRING","value":"Preservation of the dissipativity properties of a class of nonsmooth dynamical systems with the (θ,γ)-algorithm"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2011-05-30"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:edutice.archives-ouvertes.fr:edutice-00000606\",\"titles\":[\"État de l\\u0027art sur la notion de compétence. Texte introductif au séminaire national INRP\"],\"abstracts\":[\"Dans le cadre de notre recherche coopérative sur les compétences que les enseignants doivent mobiliser pour utiliser les TIC dans leurs activités, il nous a semblé nécessaire de faire le point sur la notion même de compétence. En effet les changements importants entraînés par l\\u0027introduction des technologies de l\\u0027information dans toutes les activités professionnelles affectent également les outils dont disposent les analystes de l\\u0027action. Dresser un état de l\\u0027art sur ces concepts de classement des « qualités » dont tout acteur doit faire preuve en situation de travail nous aidera peut-être à avancer des hypothèses sur les spécificités que nous cherchons à définir.\\u003cbr /\\u003eAprès une définition succincte du concept de compétence et des éléments de critique de son utilisation dans le domaine de la formation, nous ferons un bref rappel sur les théories de l\\u0027activité humaine. Puis nous approfondirons les définitions du terme, ses composantes (individuelle et collective) et les conditions de sa mise en œuvre (notamment les ressources à mobiliser) dans le cadre des activités professionnelles. Des notions voisines (qualification) et complémentaires (performance, évaluation) seront ensuite abordées, ainsi que les différents paramètres concernant l\\u0027acquisition des compétences.\\u003cbr /\\u003eLe métier d\\u0027enseignant (ou de formateur) possédant plusieurs spécificités, la définition de sa professionnalité a donné lieu à plusieurs travaux que nous essayerons de lister, revenant ainsi sur les compétences attendues (en général) de ces acteurs et les moyens de leur acquisition.\\u003cbr /\\u003eEnfin la partie concernant les compétences TIC proprement dites se présentera sous forme d\\u0027hypothèses et de questions que nous espérons faire avancer collectivement dans le cadre de notre recherche.\\u003cbr /\\u003eL\\u0027étude repose principalement sur des documents francophones récents.\"],\"language\":\"fra/fre\",\"subjects\":[\"[SHS:EDU] Humanities and Social Sciences/Education\",\"[SHS:EDU] Sciences de l\\u0027Homme et Société/Education\"],\"creators\":[\"Lévy, Jean-François\"],\"publicationdate\":\"2000-06-26\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"http://edutice.archives-ouvertes.fr/edutice-00000606\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"https://edutice.archives-ouvertes.fr/edutice-00000606\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://edutice.archives-ouvertes.fr/edutice-00000606\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://edutice.archives-ouvertes.fr/edutice-00000606\",\"id\":\"oai:HAL:edutice-00000606v1\"},\"trust\":0.059551597}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:edutice.archives-ouvertes.fr:edutice-00000606"},"target_publication_author_list":{"type":"LIST_STRING","value":["Lévy, Jean-François"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:edutice-00000606v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[SHS:EDU] Humanities and Social Sciences/Education","[SHS:EDU] Sciences de l\u0027Homme et Société/Education"]},"trust":{"type":"FLOAT","value":0.059551597},"target_publication_title":{"type":"STRING","value":"État de l\u0027art sur la notion de compétence. 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En effet les changements importants entraînés par l\\u0027introduction des technologies de l\\u0027information dans toutes les activités professionnelles affectent également les outils dont disposent les analystes de l\\u0027action. Dresser un état de l\\u0027art sur ces concepts de classement des « qualités » dont tout acteur doit faire preuve en situation de travail nous aidera peut-être à avancer des hypothèses sur les spécificités que nous cherchons à définir.\\u003cbr /\\u003eAprès une définition succincte du concept de compétence et des éléments de critique de son utilisation dans le domaine de la formation, nous ferons un bref rappel sur les théories de l\\u0027activité humaine. Puis nous approfondirons les définitions du terme, ses composantes (individuelle et collective) et les conditions de sa mise en œuvre (notamment les ressources à mobiliser) dans le cadre des activités professionnelles. Des notions voisines (qualification) et complémentaires (performance, évaluation) seront ensuite abordées, ainsi que les différents paramètres concernant l\\u0027acquisition des compétences.\\u003cbr /\\u003eLe métier d\\u0027enseignant (ou de formateur) possédant plusieurs spécificités, la définition de sa professionnalité a donné lieu à plusieurs travaux que nous essayerons de lister, revenant ainsi sur les compétences attendues (en général) de ces acteurs et les moyens de leur acquisition.\\u003cbr /\\u003eEnfin la partie concernant les compétences TIC proprement dites se présentera sous forme d\\u0027hypothèses et de questions que nous espérons faire avancer collectivement dans le cadre de notre recherche.\\u003cbr /\\u003eL\\u0027étude repose principalement sur des documents francophones récents.\"],\"language\":\"fra/fre\",\"subjects\":[\"[SHS.EDU] Humanities and Social Sciences/Education\"],\"creators\":[\"Lévy, Jean-François\"],\"publicationdate\":\"2000-06-26\",\"publisher\":\"HAL CCSD\",\"embargoenddate\":\"\",\"contributor\":[\"Technologies nouvelles et éducation (TECNE) ; INRP\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"https://edutice.archives-ouvertes.fr/edutice-00000606\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://edutice.archives-ouvertes.fr/edutice-00000606\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://edutice.archives-ouvertes.fr/edutice-00000606\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://edutice.archives-ouvertes.fr/edutice-00000606\",\"id\":\"oai:edutice.archives-ouvertes.fr:edutice-00000606\"},\"trust\":0.5224588}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:edutice-00000606v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Lévy, Jean-François"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:edutice.archives-ouvertes.fr:edutice-00000606"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[SHS.EDU] Humanities and Social Sciences/Education"]},"trust":{"type":"FLOAT","value":0.5224588},"target_publication_title":{"type":"STRING","value":"État de l\u0027art sur la notion de compétence. Texte introductif au séminaire national INRP"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2000-06-26"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2464094\",\"titles\":[\"Bioaccumulative and conchological assessment of heavy metal transfer in a soil-plant-snail food chain\"],\"abstracts\":[\"Background Copper (Cu), zinc (Zn), cadmium (Cd), and lead (Pb) can pose serious threats to environmental health because they tend to bioaccumulate in terrestrial ecosystems. We investigated under field conditions the transfer of these heavy metals in a soil-plant-snail food chain in Banat area, Romania. The main goal of this paper was to assess the Roman snail (Helix pomatia) usefulness in environmental monitoring as bioindicator of heavy metal accumulation. Eight sampling sites, selected by different history of heavy metal (HM) exposure, were chosen to be sampled for soil, nettle leaves, and newly matured snails. This study also aimed to identify the putative effects of HM accumulation in the environment on phenotypic variability in selected shell features, which included shell height (SH), relative shell height (RSH), and whorl number (WN). Results Significantly higher amounts of HMs were accumulated in snail hepatopancreas and not in foot. Cu, Zn, and Cd have biomagnified in the snail body, particularly in the hepatopancreas. In contrast, Pb decreased when going up into the food chain. Zn, Cd, and Pb correlated highly with each other at all levels of the investigated food chain. Zn and Pb exhibited an effective soil–plant transfer, whereas in the snail body only foot Cu concentration was correlated with that in soil. There were significant differences among sampling sites for WN, SH, and RSH when compared with reference snails. WN was strongly correlated with Cd and Pb concentrations in nettle leaves but not with Cu and Zn. SH was independent of HM concentrations in soil, snail hepatopancreas, and foot. However, SH correlated negatively with nettle leaves concentrations for each HM except Cu. In contrast, RSH correlated significantly only with Pb concentration in hepatopancreas. Conclusions The snail hepatopancreas accumulates high amounts of HMs, and therefore, this organ can function as a reliable biomarker for tracking HM bioavailability in soil. Long-term exposure to HMs via contaminated food might influence the variability of shell traits in snail populations. Therefore, our results highlight the Roman snail (Helix pomatia) potential to be used in environmental monitoring studies as bioindicator of HM pollution.\"],\"language\":\"eng\",\"subjects\":[\"Research Article\",\"Helix pomatia\",\"Bioindicator\",\"Environmental monitoring\",\"Heavy metal accumulation\",\"Food chain\",\"Risk assessment\"],\"creators\":[\"Nica, Dragos V.\",\"Bura, Marian\",\"Gergen, Iosif\",\"Harmanescu, Monica\",\"Bordean, Despina-Maria\"],\"publicationdate\":\"2012-06-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Chemistry Central Journal\",\"issn\":\"\",\"eissn\":\"1752-153X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1752-153X-6-55\",\"type\":\"doi\"},{\"value\":\"PMC3472253\",\"type\":\"pmc\"},{\"value\":\"22703871\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3472253\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://journal.chemistrycentral.com/content/6/1/55\",\"license\":\"OPEN\",\"hostedby\":\"Chemistry Central Journal\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://journal.chemistrycentral.com/content/6/1/55\",\"license\":\"OPEN\",\"hostedby\":\"Chemistry Central Journal\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://journal.chemistrycentral.com/content/6/1/55\",\"id\":\"oai:doaj.org/article:29c8573396e8484baea9e074bb270c2e\"},\"trust\":0.61085105}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2464094"},"target_publication_author_list":{"type":"LIST_STRING","value":["Nica, Dragos V.","Bura, Marian","Gergen, Iosif","Harmanescu, Monica","Bordean, Despina-Maria"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:29c8573396e8484baea9e074bb270c2e"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research Article","Helix pomatia","Bioindicator","Environmental monitoring","Heavy metal accumulation","Food chain","Risk assessment"]},"trust":{"type":"FLOAT","value":0.61085105},"target_publication_title":{"type":"STRING","value":"Bioaccumulative and conchological assessment of heavy metal transfer in a soil-plant-snail food chain"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2012-06-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:econstor.eu:10419/66683\",\"titles\":[\"Examinando la prominente posición de Chile a nivel mundial en cuanto a desigualdad de ingresos: Comparaciones regionales\"],\"abstracts\":[\"In the Latin American context, Chile has the highest level of per capita income and the human development index, though the distribution of income is quite unequal. Unlike Uruguay, Chile has one of the more unequal income distributions of the region. In 2003, Chile had Gini Coefficient of 8.5 points higher than Uruguay. Using micro/simulations, the analysis shows that most of the difference regarding income distribution comes from the wealthier households, particularly those that belong to the top 2%. Those households get the greatest proportion of resources coming from non-labor income. At the same time, the difference in returns to higher education explains another 20% of the income differences between Chile and Uruguay. Social conditions such as social security benefits and the participation of women in the labor market are not significant to explain the differences between these countries. 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Our data do not support such a mechanism for regulating the release of assembled NMDA receptors from the ER. We found that the motif, HLFY, immediately following transmembrane domain 4 of the NR2 subunit, is required for the assembled complex to exit from the ER. Mutation of this motif allowed the assembly of NR1 and NR2 subunits into a complex that was functional, based on MK-801 binding, but it is retained in the ER. 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We explored the frequency of PA among HIV patients (pts) treated with multi-pill protease inhibitor (PI), raltegravir (RAL), and non-nucleoside reverse transcriptase inhibitor (NNRTI) regimens and associations with hospitalizations and costs. Methods We analyzed healthcare claims from a US Medicaid population. Patients with an HIV diagnosis from 1/09 to 12/11 receiving complete ART (2 NRTIs plus a NNRTI, PI, or RAL) for ≥90 days as a STR or 2+ tablets daily were selected. Adherence and costs were observed from initiation until discontinuation of the entire regimen, switching third component classes, or database end. Adherence was reported as the percent of days (from pharmacy refill data) having a complete regimen, PA, or no medication. A logistic model assessed predictors of hospitalizations and a generalized linear model assessed healthcare costs with covariates for PA and complete non-adherence (CNA), third component, demographics, and prior ART use. Results N\\u003d1,878 STR, 729 RAL, 3,556 PI, and 775 NNRTI pts. CNA was similar across cohorts: 14.3% (46.4 days[d]) for STR, 14.0% (40.8 d) for RAL, 15.5% (53.0 d) for PI, and 13.5% (51.7 d) for multi pill NNRTI regimens. PA was seen in 12.1% (39.7 d) for RAL, 6.9% (31.7 d) for NNRTI, and 6.6% (26.7 d) for PI regimens. Thus, pts on STR had the highest percent of days (85.7%) with complete adherence to their regimen, vs. pts on multi pill RAL (73.9%), PI (77.9%), and NNRTI (79.6%) regimens. Likelihood of hospitalization significantly increased with both PA and CNA. Compared to \\u003c10 days of PA, the risk of hospitalization significantly increased (all p\\u003c0.05) with degree of incomplete adherence. For 20–30 days, the odds ratio [OR] was 1.34 for PA, and 1.45 for CNA. The OR was 1.74 for PA and 2.00 for \\u003e50 days CNA. Adjusted monthly healthcare costs were significantly greater for patients who were partially adherent for \\u003e5% of days (mean [SD] $5,108 [$1,315]) vs. ≤5% of days ($3,602[$894]). Conclusions Patients on multi pill PI, RAL, and NNRTI regimens had significantly lower complete adherence vs. STR users, mainly due to PA to a multi-pill regimens. PA and CNA to multi-pill PI, RAL, and NNRTI regimens are independently associated with a significant increase in hospitalizations and healthcare cost.\"],\"language\":\"eng\",\"subjects\":[\"Poster Abstract – P1\"],\"creators\":[\"Cohen, C.\",\"Davis, K.\",\"Meyers, J.\"],\"publicationdate\":\"2012-11-01\",\"publisher\":\"International AIDS Society\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Journal of the International AIDS Society\",\"issn\":\"\",\"eissn\":\"1758-2652\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.7448/IAS.15.6.18060\",\"type\":\"doi\"},{\"value\":\"PMC3512469\",\"type\":\"pmc\"},{\"value\":\"23217766\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3512469\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.jiasociety.org/index.php/jias/article/view/18060/1478\",\"license\":\"OPEN\",\"hostedby\":\"Journal of the International AIDS Society\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.jiasociety.org/index.php/jias/article/view/18060/1478\",\"license\":\"OPEN\",\"hostedby\":\"Journal of the International AIDS Society\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.jiasociety.org/index.php/jias/article/view/18060/1478\",\"id\":\"oai:doaj.org/article:57feac38bf0740ce9a71b31f76581798\"},\"trust\":0.45863622}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2515939"},"target_publication_author_list":{"type":"LIST_STRING","value":["Cohen, C.","Davis, K.","Meyers, J."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:57feac38bf0740ce9a71b31f76581798"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Poster Abstract – P1"]},"trust":{"type":"FLOAT","value":0.45863622},"target_publication_title":{"type":"STRING","value":"Association of partial adherence (PA) to antiretroviral therapy with hospitalizations and healthcare costs in an HIV population"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2012-11-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:docs.lib.purdue.edu:lars_symp-1341\",\"titles\":[\"A Model of Plant Canopy Polarization Response\"],\"abstracts\":[\"Sensors to remotely measure the linear polarization of ground scenes have been proposed for the Multispectral Resource Sampler (MRS), a satellite sensor system proposed to compliment the Thematic Mapper. At present justification for a sensor on MRS to measure scene polarization is limited. This paper discusses a model for the amount of linearly polarized light reflected by the shiny leaves of such crops as wheat, corn, and sorghum. The theory demonstrates that, potentially, measurements of the linearly polarized light from a crop canopy may be used as an additional feature to discriminate between crops. Examination of the model suggests that, potentially, satellite polarization measurements may be used to monitor crop development stage, leaf water content, leaf area index, hail damage, and certain plant diseases. The model adds to our understanding of the potential information content of scene polarization measurements acquired by future satellite sensor systems such as MRS.\"],\"language\":\"und\",\"subjects\":[],\"creators\":[\"Vanderbilt, V. 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Työn tavoitteena oli rakentaa käyttäjäystävällinen ja turvallinen verkkosivusto kaupalliseen käyttöön. Sivuston avulla yritys kykenee luomaan suhteita uusiin asiakkaisiin ja yhteistyökumppaneisiin sekä parantamaan liiketoimintaa entisestään. Toimeksianto saatiin Vixplatin perustajalta, Virve Mäkikankaalta. Extranetin ylläpitämiseksi luotiin hallintapaneeli, jonka avulla järjestelmään kirjautuneet pystyvät tekemään muutoksia sivustoon. Verkkosivusto toteuttiin yhdessä toimeksiantajan kanssa ja siinä hyödynnettiin molemmin puolin syntyneitä ideoita ja ajatuksia. \\n\\nSivusto toteutettiin monilla ohjelmoinnin kielillä kuten esim. HTML-, PHP- ja CSS-kielillä sekä JavaScriptin koodeilla. Extranetin pohjalle luotiin MySQL-relaatiotietokanta, jota käytetään sivuston dynaamisiin toimintoihin. Kuvankäsittelyssä käytettiin Photoshop CS3:n trial eli kokeiluversiota (30 pv). 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The site would allow the company to create new relationships with customers and partners, and to improve their business activity even more. The commission was given by the founder of Vixplate, Ms Virve Mäkikangas. The control panel was created to maintain the extranet, where people logged in the system are able to make changes to the website. The website was carried out with the commissioner and generated ideas and thoughts were used on both sides.\\n\\nThe website was implemented in many programming languages, such as HTML, PHP and CSS and also with JavaScript codes. MySQL relational database was created on to the base of extranet which is used for site’s dynamic functions. Photoshop CS3’s trial version was used for image processing (30 days). The website’s programming and cod-ing were carried out with a free Notepad++ editor, which is more a developed version of Windows’ Notepad. The result of the thesis was a dynamic website which is easy-to-use and graphically with a high level and safe. \\n\\nWebsite requires the use of Internet browsers which allow viewing the website. The site uses MMD’s leased commercial server and the relational database. The Server offers potential support for the PHP language and MySQL database. The extranet was com-pleted well in accordance with the plan and any problems encountered were corrected before publication. Customers are able to browse products, watch videos, and make requests and give feedback.\"],\"language\":\"fin\",\"subjects\":[],\"creators\":[\"Nguyen, Thang\"],\"publicationdate\":\"2010-01-01\",\"publisher\":\"Lapin ammattikorkeakoulu\",\"embargoenddate\":\"\",\"contributor\":[\"Kemi-Tornion ammattikorkeakoulu\",\"Lapin ammattikorkeakoulu\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Theseus\"],\"pids\":[],\"instances\":[{\"url\":\"http://www.theseus.fi/handle/10024/19280\",\"license\":\"OPEN\",\"hostedby\":\"Theseus\",\"instancetype\":\"Unknown\"},{\"url\":\"http://publications.theseus.fi/handle/10024/19280\",\"license\":\"OPEN\",\"hostedby\":\"Theseus\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://publications.theseus.fi/handle/10024/19280\",\"license\":\"OPEN\",\"hostedby\":\"Theseus\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"Theseus\",\"url\":\"http://publications.theseus.fi/handle/10024/19280\",\"id\":\"oai:publications.theseus.fi:10024/19280\"},\"trust\":0.20793831}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Theseus"},"target_publication_id":{"type":"STRING","value":"oai:www.theseus.fi:10024/19280"},"target_publication_author_list":{"type":"LIST_STRING","value":["Nguyen, Thang"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:publications.theseus.fi:10024/19280"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::1ee3dfcd8a0645a25a35977997223d22"},"trust":{"type":"FLOAT","value":0.20793831},"target_publication_title":{"type":"STRING","value":"Extranet-verkkopalvelun suunnittelu ja toteutus : Vixplate-yritykselle"},"provenance_datasource_name":{"type":"STRING","value":"Theseus"},"target_dateofacceptance":{"type":"DATE","value":"2010-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::1ee3dfcd8a0645a25a35977997223d22"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:publications.theseus.fi:10024/19280\",\"titles\":[\"Extranet-verkkopalvelun suunnittelu ja toteutus : Vixplate-yritykselle\"],\"abstracts\":[\"Opinnäytetyön tarkoituksen oli suunnitella ja toteuttaa extranet-verkkopalvelu Kemissä sijaitsevalle Vixplate-yritykselle. Työn tavoitteena oli rakentaa käyttäjäystävällinen ja turvallinen verkkosivusto kaupalliseen käyttöön. Sivuston avulla yritys kykenee luomaan suhteita uusiin asiakkaisiin ja yhteistyökumppaneisiin sekä parantamaan liiketoimintaa entisestään. Toimeksianto saatiin Vixplatin perustajalta, Virve Mäkikankaalta. Extranetin ylläpitämiseksi luotiin hallintapaneeli, jonka avulla järjestelmään kirjautuneet pystyvät tekemään muutoksia sivustoon. Verkkosivusto toteuttiin yhdessä toimeksiantajan kanssa ja siinä hyödynnettiin molemmin puolin syntyneitä ideoita ja ajatuksia. \\n\\nSivusto toteutettiin monilla ohjelmoinnin kielillä kuten esim. HTML-, PHP- ja CSS-kielillä sekä JavaScriptin koodeilla. Extranetin pohjalle luotiin MySQL-relaatiotietokanta, jota käytetään sivuston dynaamisiin toimintoihin. Kuvankäsittelyssä käytettiin Photoshop CS3:n trial eli kokeiluversiota (30 pv). Sivuston ohjelmoinnit ja koodaukset suoritettiin ilmaisella Notepad++-editorilla, joka on kehittyneempi versio Windowsin Notepad:sta. Opinnäytetyön tuloksena syntyi Vixplate-yritykselle dynaaminen verkkosivusto, joka on helppokäyttöinen, graafisesti korkeatasoinen ja turvallinen. \\n\\nVerkkosivuston käyttöön vaaditaan Internet-selaimia, joiden avulla sivustoa voidaan tarkastella. Sivusto hyödyntää MMD:ltä vuokrattua kaupallista palvelinta ja relaatiotietokantaa. Palvelimelta löytyvät tukimahdollisuudet PHP-kielelle ja MySQL-tietokannalle. Extranet valmistui hyvin suunnitelmien mukaan ja mahdolliset ongelmat ovat korjattu ennen julkaisua. Asiakkaat kykenevät selaamaan tuotteita, katsomaan videoita, tekemään tarjouspyyntöjä ja palautteita.\",\"The main objective of the thesis was to design and implement an extranet network ser-vice to Vixplate company which is located in Kemi. The objective was to construct a user-friendly and secure website for commercial use. 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L\\u0027article s\\u0027intéresse à deux petits ouvrages de Kunitoshi et Kunioto publiés en 1893, qui font un usage explicitement didactique d\\u0027un procédé appelé moji-e. Le moji-e, qui permet de constuire des image (e) à l\\u0027aide de caractères d\\u0027écriture (moji), connut une fortune importante à l\\u0027époque d\\u0027Edo (1603-1868). Tout au long de son histoire, il fut essentiellement considéré comme un procédé ludique. L\\u0027article suggère toutefois que ses liens avec la culture enfantine et avec l\\u0027apprentissage du dessin ont pu faciliter son utilisation au service d\\u0027un nouveau projet éducatif, en l\\u0027occurrence l\\u0027apprentissage de l\\u0027écriture, au cours de l\\u0027ère Meiji.\"],\"language\":\"fra/fre\",\"subjects\":[\"[SHS:LITT] Humanities and Social Sciences/Literature\",\"[SHS:LITT] Sciences de l\\u0027Homme et Société/Littératures\",\"pédagogie\",\"apprentissage\",\"divertissement\",\"image\",\"écriture\",\"lecture\",\"moji-e\",\"Hokusai\",\"Kunitoshi\",\"Kunioto\"],\"creators\":[\"Simon-Oikawa, Marianne\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"http://hal.archives-ouvertes.fr/hal-00749645\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Part of book or chapter of book\"},{\"url\":\"https://hal.archives-ouvertes.fr/hal-00749645\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00749645\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.archives-ouvertes.fr/hal-00749645\",\"id\":\"oai:HAL:hal-00749645v1\"},\"trust\":0.013272405}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:hal.archives-ouvertes.fr:hal-00749645"},"target_publication_author_list":{"type":"LIST_STRING","value":["Simon-Oikawa, Marianne"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:hal-00749645v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[SHS:LITT] Humanities and Social Sciences/Literature","[SHS:LITT] Sciences de l\u0027Homme et Société/Littératures","pédagogie","apprentissage","divertissement","image","écriture","lecture","moji-e","Hokusai","Kunitoshi","Kunioto"]},"trust":{"type":"FLOAT","value":0.013272405},"target_publication_title":{"type":"STRING","value":"Du divertissement à l\u0027enseignement par l\u0027image : les usages pédagogiques des images en écriture (moji-e) au Japon"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:hal-00749645v1\",\"titles\":[\"Du divertissement à l\\u0027enseignement par l\\u0027image : les usages pédagogiques des images en écriture (moji-e) au Japon\"],\"abstracts\":[\"International audience\",\"The implementation of mass education in Japan during the Meiji period (1868-1912) led to the publication of a considerable amount of educational material meant to be used at school and at home. The papers concentrates on two little books by Kunitoshi and Kunioto published in 1893, that make extensive use of a technique called moji-e Moji-e amounts to creating images with a few kanji or kana, and was extremely popular through the Edo period (1603-1868). Throughout its history, it was mostly seen as playful. Yet, the paper suggests that its relationship with children\\u0027s culture and the teaching of drawing may have made it easier to use it for a new educational purpose, namely the teaching of writing, during the Meiji era.\",\"La mise en place d\\u0027un système éducatif de masse au Japon au cours de l\\u0027ère Meiji (1868-1912) suscita la multiplication de publications pédagogiques, destinées au cadre scolaire aussi bien que domestique. L\\u0027article s\\u0027intéresse à deux petits ouvrages de Kunitoshi et Kunioto publiés en 1893, qui font un usage explicitement didactique d\\u0027un procédé appelé moji-e. Le moji-e, qui permet de constuire des image (e) à l\\u0027aide de caractères d\\u0027écriture (moji), connut une fortune importante à l\\u0027époque d\\u0027Edo (1603-1868). Tout au long de son histoire, il fut essentiellement considéré comme un procédé ludique. L\\u0027article suggère toutefois que ses liens avec la culture enfantine et avec l\\u0027apprentissage du dessin ont pu faciliter son utilisation au service d\\u0027un nouveau projet éducatif, en l\\u0027occurrence l\\u0027apprentissage de l\\u0027écriture, au cours de l\\u0027ère Meiji.\"],\"language\":\"fra/fre\",\"subjects\":[\"Kunioto\",\"Kunitoshi\",\"Hokusai\",\"moji-e\",\"reading\",\"writing\",\"image\",\"play\",\"learning\",\"education\",\"Kunioto\",\"moji-e\",\"Hokusai\",\"Kunitoshi\",\"lecture\",\"écriture\",\"image\",\"divertissement\",\"apprentissage\",\"pédagogie\",\"[SHS.LITT] Humanities and Social Sciences/Literature\"],\"creators\":[\"Simon-Oikawa, Marianne\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"Presses universitaires de Rennes\",\"embargoenddate\":\"\",\"contributor\":[\"Equipe Japon ; Centre de recherche sur les civilisations de l\\u0027Asie Orientale (CRCAO) ; Collège de France - Université Paris VII - Paris Diderot - École Pratique des Hautes Études [EPHE] - CNRS - Collège de France - Université Paris VII - Paris Diderot - École Pratique des Hautes Études [EPHE] - CNRS\",\"Annie Renonciat et Marianne Simon-Oikawa\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00749645\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://hal.archives-ouvertes.fr/hal-00749645\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Part of book or chapter of book\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hal.archives-ouvertes.fr/hal-00749645\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Part of book or chapter of book\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://hal.archives-ouvertes.fr/hal-00749645\",\"id\":\"oai:hal.archives-ouvertes.fr:hal-00749645\"},\"trust\":0.9736765}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:hal-00749645v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Simon-Oikawa, Marianne"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:hal.archives-ouvertes.fr:hal-00749645"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Kunioto","Kunitoshi","Hokusai","moji-e","reading","writing","image","play","learning","education","Kunioto","moji-e","Hokusai","Kunitoshi","lecture","écriture","image","divertissement","apprentissage","pédagogie","[SHS.LITT] Humanities and Social Sciences/Literature"]},"trust":{"type":"FLOAT","value":0.9736765},"target_publication_title":{"type":"STRING","value":"Du divertissement à l\u0027enseignement par l\u0027image : les usages pédagogiques des images en écriture (moji-e) au Japon"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MISSING/PID","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:muc:wpaper:201142\",\"titles\":[\"Employed But Still Unhappy? 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Ze vragen zich af hoe zoiets mogelijk is in een land dat\\nbekendstaat als baken van seculiere tolerantie. Dit roept de vraag op hoe etnische\\ntolerantie en afwijzing van traditionele christelijke stellingnamen over morele\\nvraagstukken zich tot elkaar verhouden. In dit artikel onderzoeken we daarom of\\nen waarom het aanhangen van een post-Christelijke moraal voor sommigen leidt\\ntot etnische intolerantie, terwijl het voor anderen samengaat met etnische tolerantie.\"],\"language\":\"dut/nld\",\"subjects\":[],\"creators\":[\"Koster, W.\",\"Houtman, D.\",\"Waal, J.\"],\"publicationdate\":\"2010-11-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Erasmus University Institutional Repository\"],\"pids\":[],\"instances\":[{\"url\":\"http://repub.eur.nl/pub/26139\",\"license\":\"OPEN\",\"hostedby\":\"Erasmus University Institutional Repository\",\"instancetype\":\"Article\"},{\"url\":\"http://hdl.handle.net/1765/26139\",\"license\":\"OPEN\",\"hostedby\":\"Erasmus University Institutional Repository\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/1765/26139\",\"license\":\"OPEN\",\"hostedby\":\"Erasmus University Institutional Repository\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"NARCIS\",\"url\":\"http://hdl.handle.net/1765/26139\",\"id\":\"eur:oai:repub.eur.nl:26139\"},\"trust\":0.21302724}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Erasmus University Institutional Repository"},"target_publication_id":{"type":"STRING","value":"oai:repub.eur.nl:26139"},"target_publication_author_list":{"type":"LIST_STRING","value":["Koster, W.","Houtman, D.","Waal, J."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["eur:oai:repub.eur.nl:26139"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::fdb035c8b3e0540a8d9a561a6c44f4de"},"trust":{"type":"FLOAT","value":0.21302724},"target_publication_title":{"type":"STRING","value":"Van God los: Post-Christelijk cultureel conflict in Nederland."},"provenance_datasource_name":{"type":"STRING","value":"NARCIS"},"target_dateofacceptance":{"type":"DATE","value":"2010-11-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9c3b1830513cc3b8fc4b76635d32e692"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3360964\",\"titles\":[\"Infliximab Preferentially Induces Clinical Remission and Mucosal Healing in Short Course Crohn\\u0027s Disease with Luminal Lesions through Balancing Abnormal Immune Response in Gut Mucosa\"],\"abstracts\":[\"This study was undertaken to evaluate the efficacy of infliximab (IFX) in treatment of Crohn\\u0027s disease (CD) patients. 106 CD patients were undergoing treatment with IFX from five hospitals in Shanghai, China. Clinical remission to IFX induction therapy was defined as Crohn\\u0027s disease activity index (CDAI) \\u003c 150. Clinical response was assessed by a decrease in CDAI ≥ 70, and the failure as a CDAI was not significantly changed or increased. Ten weeks after therapy, 61 (57.5%) patients achieved clinical remission, 17 (16.0%) had clinical response, and the remaining 28 (26.4%) were failed. In remission group, significant changes were observed in CDAI, the Simple Endoscopic Score for Crohn\\u0027s Disease (SES-CD), and serum indexes. Patients with short disease duration (22.2 ± 23.2 months) and luminal lesions showed better effects compared to those with long disease duration (71.0 ± 58.2 months) or stricturing and penetrating lesions. IFX markedly downregulated Th1/Th17-mediated immune response but promoted IL-25 production in intestinal mucosa from remission group. No serious adverse events occurred to terminate treatment. Taken together, our studies demonstrated that IFX is efficacious and safe in inducing clinical remission, promoting mucosal healing, and downregulating Th1/Th17-mediated immune response in short course CD patients with luminal lesions.\"],\"language\":\"eng\",\"subjects\":[\"Clinical Study\"],\"creators\":[\"Yu, Lijuan\",\"Yang, Xuehua\",\"Xia, Lu\",\"Zhong, Jie\",\"Ge, Wensong\",\"Wu, Jianxin\",\"Liu, Hongchun\",\"Liu, Fei\",\"Liu, Zhanju\"],\"publicationdate\":\"2015-03-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Mediators of Inflammation\",\"issn\":\"0962-9351\",\"eissn\":\"1466-1861\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2015/793764\",\"type\":\"doi\"},{\"value\":\"PMC4383520\",\"type\":\"pmc\"},{\"value\":\"25873771\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4383520\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2015/793764\",\"license\":\"OPEN\",\"hostedby\":\"Mediators of Inflammation\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2015/793764\",\"license\":\"OPEN\",\"hostedby\":\"Mediators of Inflammation\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2015/793764\",\"id\":\"oai:doaj.org/article:c9a19ec8d4de4a82a6061bdaba3b9653\"},\"trust\":0.6343591}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3360964"},"target_publication_author_list":{"type":"LIST_STRING","value":["Yu, Lijuan","Yang, Xuehua","Xia, Lu","Zhong, Jie","Ge, Wensong","Wu, Jianxin","Liu, Hongchun","Liu, Fei","Liu, Zhanju"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:c9a19ec8d4de4a82a6061bdaba3b9653"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Clinical Study"]},"trust":{"type":"FLOAT","value":0.6343591},"target_publication_title":{"type":"STRING","value":"Infliximab Preferentially Induces Clinical Remission and Mucosal Healing in Short Course Crohn\u0027s Disease with Luminal Lesions through Balancing Abnormal Immune Response in Gut Mucosa"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2015-03-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2832450\",\"titles\":[\"Association of Endothelial Dysfunction with Endothelin, Nitric Oxide and eNOS Glu298Asp Gene Polymorphism in Coronary Artery Disease\"],\"abstracts\":[\"The endothelial dysfunction has been implicated as a major event in the pathogenesis of atherosclerosis. Therefore, this study was planned to determine (a) role of endothelium-derived nitric oxide (NO) and endothelin as coronary artery disease (CAD) risk markers and (b) intergenotypic variation of endothelial nitric oxide synthase (eNOS) Glu298Asp polymorphism in CAD.The endothelin, NO and eNOS genotypes were determined in 60 patients with documented history of CAD. These were compared with 50 age- and sex- matched healthy controls. The genotype frequencies for eNOS gene polymorphism were determined by PCR and RFLP. The plasma endothelin in CAD patients was significantly higher (p \\u003c 0.001) whereas, the NO level in CAD group was significantly lower (p \\u003c 0.001) than the control group. The genotype frequencies for Glu298/Asp (Glu/Glu and Glu/Asp) genotypes were 75% and 25% in CAD subjects and 88% and 12% in control subjects, respectively. No Asp/Asp was found in any of the groups. The genotype frequencies differed significantly (p \\u003c 0.05) between the controls and cases. In conclusion, endothelin and NO may be used as markers of endothelial dysfunction in CAD. Asp allele might be a risk factor for CAD in the North Indian population.\"],\"language\":\"eng\",\"subjects\":[\"Other\",\"Nitric oxide\",\"Coronary artery disease\",\"Glu298Asp polymorphism\",\"endothelin\"],\"creators\":[\"Saini, Vandana\",\"Bhatnagar, M. 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We present a detailed calculation of the cosmological\\nperturbations in this setup. We use the recent observational data from the joint\\ndata set of WMAP9 + BAO + \\u003cmath id\\u003d\\\"M1\\\" xmlns\\u003d\\\"http://www.w3.org/1998/Math/MathML\\\"\\u003e\\u003cmrow\\u003e\\u003cmsub\\u003e\\u003cmrow\\u003e\\u003cmi\\u003eH\\u003c/mi\\u003e\\u003c/mrow\\u003e\\u003cmrow\\u003e\\u003cmn\\u003e0\\u003c/mn\\u003e\\u003c/mrow\\u003e\\u003c/msub\\u003e\\u003c/mrow\\u003e\\u003c/math\\u003e and also the Planck satellite data to constrain our\\nmodel parameters for natural and chaotic inflation potentials. 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An integrated e(+)p luminosity of 114.8 pb(-1) and e(-)p luminosity of 16.7 pb(-1) were used. No evidence for any resonance was found. Limits were derived on the Yukawa coupling lambda as a function of the mass of a hypothetical resonance that has arbitrary decay branching ratios into eq or nuq. These limits also apply to squarks predicted by R-parity-violating supersymmetry. Limits for the production of leptoquarks described by the Buchmuller-Ruckl- Wyler model were also derived for masses up to 400 GeV. For lambda\\u003d0.1, leptoquark masses up to 290 GeV are excluded. \"],\"language\":\"eng\",\"subjects\":[\"QC Physics\"],\"creators\":[\"Chekanov, S.\",\"Derrick, M.\",\"Krakauer, D.\",\"Loizides, J. H.\",\"Magill, S.\",\"Musgrave, B.\",\"Repond, J.\",\"Yoshida, R.\",\"Mattingly, M. C. 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Six domestic maize\\n hybrids (B1 \\u003d Os298P, B2 \\u003d Tvrtko303, B3 \\u003d Os444, B4 \\u003d Os499, B5 \\u003d Os552 and\\n B6 \\u003d Os596) were sown at beginning of May (basic plot 24 m2). The ear-leaf of\\n maize was collected at flowering and grain in maturity of the 2006 and 2007\\n growing seasons. Boron and molybdenum in the samples were determined by the\\n ICP-OES method. The growing season 2006 was favorable for maize growth, while\\n 2007 characterized stress due to drought and high air-temperatures. B and Mo\\n concentrations (2-yr means) in grains were considerably lower for 12-fold (B)\\n and close to two-fold (Mo) in comparison with the leaves. Leaf-Mo in 2007 was\\n about 50% lower in comparison with 2006 (0.310 and 0.149 mg Mo kg-1,\\n respectively). Mean differences among the hybrids (mg kg-1) were as follows:\\n leaf-B 9.3 (B1) to 21.4 (B3) and grain-B 1.00 (B2) to 1.50 (B3); leaf-Mo\\n 0.157 (B5) to 0.361 (B3) and grain-Mo 0.109 (B5) to 0.137 (B1). As affected\\n by liming leaf-Mo were increased compared with the control 2.5-fold and 4.1\\n fold, grain-Mo 3.8-fold and 4.6-fold, for 5 and 20 t ha-1 lime, respectively.\\n Liming effects on B concentrations in maize were considerably lower, because\\n non-significant differences for leaf-B in 2006 and decrease for 36% in 2007\\n were found.\"],\"language\":\"und\",\"subjects\":[\"boron\",\"molybdenum\",\"grain\",\"leaf\",\"liming\",\"maize hybrids\"],\"creators\":[\"Kovačević Vlado\",\"Šimić Domagoj\",\"Zdunić Zvonimir\",\"Lončarić Zdenko\"],\"publicationdate\":\"2013-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"National Library of Serbia - Digital Object Identifier Repository\"],\"pids\":[{\"value\":\"10.2298/GENSR1302419K\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://dx.doi.org/10.2298/GENSR1302419K\",\"license\":\"OPEN\",\"hostedby\":\"National Library of Serbia - Digital Object Identifier Repository\",\"instancetype\":\"Unknown\"},{\"url\":\"http://www.doiserbia.nb.rs/img/doi/0534-0012/2013/0534-00121302419K.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Genetika\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.doiserbia.nb.rs/img/doi/0534-0012/2013/0534-00121302419K.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Genetika\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.doiserbia.nb.rs/img/doi/0534-0012/2013/0534-00121302419K.pdf\",\"id\":\"oai:doaj.org/article:cc3497a8da43451bab937548d6ef2b64\"},\"trust\":0.6789191}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"National Library of Serbia - Digital Object Identifier Repository"},"target_publication_id":{"type":"STRING","value":"oai:doiserbia:0534-00121302419K"},"target_publication_author_list":{"type":"LIST_STRING","value":["Kovačević Vlado","Šimić Domagoj","Zdunić Zvonimir","Lončarić Zdenko"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:cc3497a8da43451bab937548d6ef2b64"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["boron","molybdenum","grain","leaf","liming","maize hybrids"]},"trust":{"type":"FLOAT","value":0.6789191},"target_publication_title":{"type":"STRING","value":"Genotype and liming impacts on boron and molybdenum status in maize"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2013-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::1aa48fc4880bb0c9b8a3bf979d3b917e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MISSING/PID","payload":"{\"publication\":{\"originalId\":\"oai:lirias.kuleuven.be:123456789/493514\",\"titles\":[\"Three-body forces and shell structure in calcium isotopes\"],\"abstracts\":[\"Understanding and predicting the formation of shell structure from nuclear\\nforces is a central challenge for nuclear physics. While the magic numbers\\nN\\n\\u003d\\n2\\n,\\n8\\n,\\n20 are generally well understood,\\nN\\n\\u003d\\n28 is the first standard\\nmagic number that is not reproduced in microscopic theories with two-nucleon\\nforces. In this paper, we show that three-nucleon forces give rise to repulsive\\ninteractions between two valence neutrons that are key to explain\\n48\\nCa as a\\nmagic nucleus, with a high 2\\n+\\nexcitation energy and a concentrated magnetic\\ndipole transition strength. The repulsive three-nucleon mechanism improves\\nthe agreement with experimental binding energies.\",\"status: published\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Holt, Jason D.\",\"Otsuka, Taka\",\"Schwenk, Achim\",\"Suzuki, Toshio\"],\"publicationdate\":\"2012-01-01\",\"publisher\":\"BRISTOL\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Lirias\"],\"pids\":[{\"value\":\"10.1088/0954-3899/39/8/085111\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"https://lirias.kuleuven.be/handle/123456789/493514\",\"license\":\"OPEN\",\"hostedby\":\"Lirias\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"pids\":[{\"value\":\"10.1088/0954-3899/39/8/085111\",\"type\":\"doi\"}]},\"provenance\":{\"repositoryName\":\"arXiv.org e-Print Archive\",\"url\":\"http://arxiv.org/abs/1009.5984\",\"id\":\"oai:arXiv.org:1009.5984\"},\"trust\":0.43124872}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Lirias"},"target_publication_id":{"type":"STRING","value":"oai:lirias.kuleuven.be:123456789/493514"},"target_publication_author_list":{"type":"LIST_STRING","value":["Holt, Jason D.","Otsuka, Taka","Schwenk, Achim","Suzuki, Toshio"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:arXiv.org:1009.5984"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"},"trust":{"type":"FLOAT","value":0.43124872},"target_publication_title":{"type":"STRING","value":"Three-body forces and shell structure in calcium isotopes"},"provenance_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_dateofacceptance":{"type":"DATE","value":"2012-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::fe709c654eac84d5239d1a12a4f71877"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/PID","payload":"{\"publication\":{\"originalId\":\"oai:lirias.kuleuven.be:123456789/493514\",\"titles\":[\"Three-body forces and shell structure in calcium isotopes\"],\"abstracts\":[\"Understanding and predicting the formation of shell structure from nuclear\\nforces is a central challenge for nuclear physics. 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The repulsive three-nucleon mechanism improves\\nthe agreement with experimental binding energies.\",\"status: published\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Holt, Jason D.\",\"Otsuka, Taka\",\"Schwenk, Achim\",\"Suzuki, Toshio\"],\"publicationdate\":\"2012-01-01\",\"publisher\":\"BRISTOL\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Lirias\"],\"pids\":[{\"value\":\"10.1088/0954-3899/39/8/085111\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"https://lirias.kuleuven.be/handle/123456789/493514\",\"license\":\"OPEN\",\"hostedby\":\"Lirias\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"pids\":[{\"value\":\"10.1088/0954-3899/39/8/085111\",\"type\":\"doi\"}]},\"provenance\":{\"repositoryName\":\"arXiv.org e-Print Archive\",\"url\":\"http://arxiv.org/abs/1009.5984\",\"id\":\"oai:arXiv.org:1009.5984\"},\"trust\":0.43124872}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Lirias"},"target_publication_id":{"type":"STRING","value":"oai:lirias.kuleuven.be:123456789/493514"},"target_publication_author_list":{"type":"LIST_STRING","value":["Holt, Jason D.","Otsuka, Taka","Schwenk, Achim","Suzuki, Toshio"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:arXiv.org:1009.5984"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"},"trust":{"type":"FLOAT","value":0.43124872},"target_publication_title":{"type":"STRING","value":"Three-body forces and shell structure in calcium isotopes"},"provenance_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_dateofacceptance":{"type":"DATE","value":"2012-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::fe709c654eac84d5239d1a12a4f71877"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:lirias.kuleuven.be:123456789/493514\",\"titles\":[\"Three-body forces and shell structure in calcium isotopes\"],\"abstracts\":[\"Understanding and predicting the formation of shell structure from nuclear\\nforces is a central challenge for nuclear physics. 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The repulsive three-nucleon mechanism improves\\nthe agreement with experimental binding energies.\",\"status: published\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Holt, Jason D.\",\"Otsuka, Taka\",\"Schwenk, Achim\",\"Suzuki, Toshio\"],\"publicationdate\":\"2012-01-01\",\"publisher\":\"BRISTOL\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Lirias\"],\"pids\":[],\"instances\":[{\"url\":\"https://lirias.kuleuven.be/handle/123456789/493514\",\"license\":\"OPEN\",\"hostedby\":\"Lirias\",\"instancetype\":\"Article\"},{\"url\":\"http://arxiv.org/abs/1009.5984\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://arxiv.org/abs/1009.5984\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"arXiv.org e-Print Archive\",\"url\":\"http://arxiv.org/abs/1009.5984\",\"id\":\"oai:arXiv.org:1009.5984\"},\"trust\":0.61818963}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Lirias"},"target_publication_id":{"type":"STRING","value":"oai:lirias.kuleuven.be:123456789/493514"},"target_publication_author_list":{"type":"LIST_STRING","value":["Holt, Jason D.","Otsuka, Taka","Schwenk, Achim","Suzuki, Toshio"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:arXiv.org:1009.5984"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"},"trust":{"type":"FLOAT","value":0.61818963},"target_publication_title":{"type":"STRING","value":"Three-body forces and shell structure in calcium isotopes"},"provenance_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_dateofacceptance":{"type":"DATE","value":"2012-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::fe709c654eac84d5239d1a12a4f71877"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:arXiv.org:1009.5984\",\"titles\":[\"Three-body forces and shell structure in calcium isotopes\"],\"abstracts\":[\" Understanding and predicting the formation of shell structure from nuclear\\nforces is a central challenge for nuclear physics. While the magic numbers\\nN\\u003d2,8,20 are generally well understood, N\\u003d28 is the first standard magic number\\nthat is not reproduced in microscopic theories with two-nucleon forces. In this\\nLetter, we show that three-nucleon forces give rise to repulsive interactions\\nbetween two valence neutrons that are key to explain 48Ca as a magic nucleus,\\nwith a high 2+ excitation energy and a concentrated magnetic dipole transition\\nstrength. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients. \"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Schreinemakers, J. M. J.\",\"Vriens, M. R.\",\"Valk, G. D.\",\"Groot, J. W. B.\",\"Plukker, J. T.\",\"Bax, N. M. A.\",\"Hamming, J. F.\",\"Luijt, R. B.\",\"Aronson, D. C.\",\"Borel Rinkes, I. H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients. \"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Schreinemakers, J. M. J.\",\"Vriens, M. R.\",\"Valk, G. D.\",\"Groot, J. W. B.\",\"Plukker, J. T.\",\"Bax, N. M. A.\",\"Hamming, J. F.\",\"Luijt, R. B.\",\"Aronson, D. C.\",\"Borel Rinkes, I. H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients. \"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Schreinemakers, J. M. J.\",\"Vriens, M. R.\",\"Valk, G. D.\",\"Groot, J. W. B.\",\"Plukker, J. T.\",\"Bax, N. M. A.\",\"Hamming, J. F.\",\"Luijt, R. B.\",\"Aronson, D. C.\",\"Borel Rinkes, I. H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients. \"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Schreinemakers, J. M. J.\",\"Vriens, M. R.\",\"Valk, G. D.\",\"Groot, J. W. B.\",\"Plukker, J. T.\",\"Bax, N. M. A.\",\"Hamming, J. F.\",\"Luijt, R. B.\",\"Aronson, D. C.\",\"Borel Rinkes, I. H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case-control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients. \"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Schreinemakers, J. M. J.\",\"Vriens, M. R.\",\"Valk, G. D.\",\"Groot, J. W. B.\",\"Plukker, J. T.\",\"Bax, N. M. A.\",\"Hamming, J. F.\",\"Luijt, R. B.\",\"Aronson, D. C.\",\"Borel Rinkes, I. H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case–control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients.\"],\"language\":\"eng\",\"subjects\":[\"Article\"],\"creators\":[\"Schreinemakers, Jennifer M. J.\",\"Vriens, Menno R.\",\"Valk, Gerlof D.\",\"Groot, Jan-Willem B.\",\"Plukker, John T.\",\"Bax, Klaas M. A.\",\"Hamming, Jaap F.\",\"Luijt, Rob B.\",\"Aronson, Daniel C.\",\"Borel Rinkes, Inne H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case–control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients.\"],\"language\":\"eng\",\"subjects\":[\"Article\"],\"creators\":[\"Schreinemakers, Jennifer M. J.\",\"Vriens, Menno R.\",\"Valk, Gerlof D.\",\"Groot, Jan-Willem B.\",\"Plukker, John T.\",\"Bax, Klaas M. A.\",\"Hamming, Jaap F.\",\"Luijt, Rob B.\",\"Aronson, Daniel C.\",\"Borel Rinkes, Inne H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case–control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients.\"],\"language\":\"eng\",\"subjects\":[\"Article\"],\"creators\":[\"Schreinemakers, Jennifer M. J.\",\"Vriens, Menno R.\",\"Valk, Gerlof D.\",\"Groot, Jan-Willem B.\",\"Plukker, John T.\",\"Bax, Klaas M. A.\",\"Hamming, Jaap F.\",\"Luijt, Rob B.\",\"Aronson, Daniel C.\",\"Borel Rinkes, Inne H. 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All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. Methods In a nationwide case–control study, all patients who underwent total thyroidectomy in the Netherlands under the age of 20 years were classified into standard (1), high (2), or very high risk (3) for MTC based on RET-mutation type. Disease-free patients were compared with those with recurrent disease. Results A total of 93 patients were included in the study. Sixty-six percent had MTC on histology, the youngest being 1 year old. Codon 634 was most affected. Sixteen (18%) patients had persistent or recurrent disease, one of whom died. Significantly associated determinants of outcome in univariate analysis were higher age at surgery, no age-appropriate prophylactic surgery according to risk level, elevated preoperative calcitonin levels, affected codon, and the presence of lymph node metastases at surgery. On multivariate analysis only age of surgery was the single independent factor associated with persistent disease. Conclusions Prophylactic thyroidectomy beyond the recommended age is associated with persistent/recurrent disease. In addition, codon 634 mutation is associated with a high risk of recurrence requiring early surgery for all these patients.\"],\"language\":\"eng\",\"subjects\":[\"Article\"],\"creators\":[\"Schreinemakers, Jennifer M. J.\",\"Vriens, Menno R.\",\"Valk, Gerlof D.\",\"Groot, Jan-Willem B.\",\"Plukker, John T.\",\"Bax, Klaas M. A.\",\"Hamming, Jaap F.\",\"Luijt, Rob B.\",\"Aronson, Daniel C.\",\"Borel Rinkes, Inne H. M.\"],\"publicationdate\":\"2010-01-01\",\"publisher\":\"Springer-Verlag\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"World Journal of Surgery\",\"issn\":\"0364-2313\",\"eissn\":\"1432-2323\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1007/s00268-009-0370-2\",\"type\":\"doi\"},{\"value\":\"PMC2832884\",\"type\":\"pmc\"},{\"value\":\"20063095\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC2832884\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://repub.eur.nl/pub/27989\",\"license\":\"OPEN\",\"hostedby\":\"Erasmus University Institutional Repository\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://repub.eur.nl/pub/27989\",\"license\":\"OPEN\",\"hostedby\":\"Erasmus University Institutional Repository\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Erasmus University Institutional Repository\",\"url\":\"http://repub.eur.nl/pub/27989\",\"id\":\"oai:repub.eur.nl:27989\"},\"trust\":0.71005017}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:1910535"},"target_publication_author_list":{"type":"LIST_STRING","value":["Schreinemakers, Jennifer M. J.","Vriens, Menno R.","Valk, Gerlof D.","Groot, Jan-Willem B.","Plukker, John T.","Bax, Klaas M. A.","Hamming, Jaap F.","Luijt, Rob B.","Aronson, Daniel C.","Borel Rinkes, Inne H. M."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:repub.eur.nl:27989"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9c3b1830513cc3b8fc4b76635d32e692"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Article"]},"trust":{"type":"FLOAT","value":0.71005017},"target_publication_title":{"type":"STRING","value":"Factors Predicting Outcome of Total Thyroidectomy in Young Patients with Multiple Endocrine Neoplasia Type 2: A Nationwide Long-Term Follow-up Study"},"provenance_datasource_name":{"type":"STRING","value":"Erasmus University Institutional Repository"},"target_dateofacceptance":{"type":"DATE","value":"2010-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3185666\",\"titles\":[\"Microbubbles coupled to methotrexate-loaded liposomes for ultrasound-mediated delivery of methotrexate across the blood–brain barrier\"],\"abstracts\":[\"Methotrexate (MTX) is the single most effective agent for the treatment of primary central nervous system lymphoma. Currently, the delivery of MTX to the brain is achieved by high systemic doses, which cause severe long-term neurotoxicity, or intrathecal administration, which is highly invasive and may lead to infections or hemorrhagic complications. Acoustically active microbubbles have been developed as drug carriers for the noninvasive and brain-targeted delivery of therapeutics. However, their application is limited by their low drug-loading capacity. To overcome this limitation, we prepared microbubbles coupled to MTX-loaded liposomes using ZHIFUXIAN, a novel type of microbubbles with a superior safety profile and long circulation time. MTX-liposome-coupled microbubbles had a high drug-loading capacity of 8.91%±0.86%, and their size (2.64±0.93 μm in diameter) was suitable for intravenous injection. When used with ultrasound, they showed more potent in vitro cytotoxicity against Walker-256 cancer cells than MTX alone or MTX-loaded liposomes. When Sprague-Dawley rats were exposed to sonication, administration of these MTX-liposome-coupled microbubbles via the tail vein led to targeted disruption of the blood–brain barrier without noticeable tissue or capillary damage. High-performance liquid chromatography analysis of the brain MTX concentration showed that MTX delivery to the brain followed the order of MTX-liposome-coupled microbubbles + ultrasound (25.3±2.4 μg/g) \\u003e unmodified ZHIFUXIAN + MTX + ultrasound (18.6±2.2 μg/g) \\u003e MTX alone (6.97±0.75 μg/g) \\u003e MTX-liposome-coupled microbubbles (2.92±0.39 μg/g). Therefore, treatment with MTX-liposome-coupled microbubbles and ultrasound resulted in a significantly higher brain MTX concentration than all other treatments (P\\u003c0.01). These results suggest that MTX-liposome-coupled microbubbles may hold great promise as new and effective therapies for primary central nervous system lymphoma and other central nervous system malignancies.\"],\"language\":\"eng\",\"subjects\":[\"Original Research\",\"methotrexate\",\"microbubbles\",\"ultrasound\",\"liposomes\",\"blood–brain barrier\"],\"creators\":[\"Wang, Xiang\",\"Liu, Ping\",\"Yang, Weixiao\",\"Li, Lu\",\"Li, Peijing\",\"Liu, Zheng\",\"Zhuo, Zhongxiong\",\"Gao, Yunhua\"],\"publicationdate\":\"2014-10-01\",\"publisher\":\"Dove Medical Press\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"International Journal of Nanomedicine\",\"issn\":\"1176-9114\",\"eissn\":\"1178-2013\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.2147/IJN.S69845\",\"type\":\"doi\"},{\"value\":\"PMC4211917\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4211917\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.dovepress.com/microbubbles-coupled-to-methotrexate-loaded-liposomes-for-ultrasound-m-peer-reviewed-article-IJN\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.dovepress.com/microbubbles-coupled-to-methotrexate-loaded-liposomes-for-ultrasound-m-peer-reviewed-article-IJN\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.dovepress.com/microbubbles-coupled-to-methotrexate-loaded-liposomes-for-ultrasound-m-peer-reviewed-article-IJN\",\"id\":\"oai:doaj.org/article:1df4c18cd94d456face78fd477394614\"},\"trust\":0.96049035}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3185666"},"target_publication_author_list":{"type":"LIST_STRING","value":["Wang, Xiang","Liu, Ping","Yang, Weixiao","Li, Lu","Li, Peijing","Liu, Zheng","Zhuo, Zhongxiong","Gao, Yunhua"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:1df4c18cd94d456face78fd477394614"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Original Research","methotrexate","microbubbles","ultrasound","liposomes","blood–brain barrier"]},"trust":{"type":"FLOAT","value":0.96049035},"target_publication_title":{"type":"STRING","value":"Microbubbles coupled to methotrexate-loaded liposomes for ultrasound-mediated delivery of methotrexate across the blood–brain barrier"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2014-10-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"\",\"titles\":[\"Engel elasticities, pseudo-maximum likelihood estimation and bootstrapped standard errors :a case study\"],\"abstracts\":[\"Abstract:Estimation of standard errors of Engel elasticities within the framework of a linear structural model formulated on two-wave panel data is considered. The complete demand system is characterized by measurement errors in total expenditure and by latent preference variation. The estimation of the parameters as well as the standard errors of the estimates is based on the assumption that the variables are normally distributed. Considering a concrete case it is demonstrated that normality does not hold as a maintained assumption. In the light of this standard errors are estimated by means of bootstrapping. However, one obtains rather similar estimates of the standard errors of the Engel elasticities no matter whether one sticks to classical normal inference or perform non-parametric bootstrapping. Keywords: Engel elasticities, standard errors, classical normal theory, bootstrapping\"],\"language\":\"eng\",\"subjects\":[\"Mathematics and natural science:Mathematics:Statistics:\",\"Matematikk og naturvitenskap:Matematikk:Statistikk:\",\"Engel elasticities\",\"Non-parametric bootstrapping\",\"Classical normal theory\",\"Linear structural model\",\"JEL classification: C13\",\"JEL classification: C14\",\"JEL classification: C15\",\"JEL classification: C33\",\"JEL classification: D12\"],\"creators\":[\"Skjerpen, Terje\"],\"publicationdate\":\"2008-01-01\",\"publisher\":\"Statistics Norway, Research Department\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Norwegian Open Research Archives\"],\"pids\":[],\"instances\":[{\"url\":\"http://idtjeneste.nb.no/URN:NBN:no-bibsys_brage_24975\",\"license\":\"OPEN\",\"hostedby\":\"Norwegian Open Research Archives\",\"instancetype\":\"Research\"},{\"url\":\"http://www.ssb.no/a/publikasjoner/pdf/DP/dp532.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.ssb.no/a/publikasjoner/pdf/DP/dp532.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}]},\"provenance\":{\"repositoryName\":\"Research Papers in Economics\",\"url\":\"http://www.ssb.no/a/publikasjoner/pdf/DP/dp532.pdf\",\"id\":\"oai:RePEc:ssb:dispap:532\"},\"trust\":0.74632466}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Norwegian Open Research Archives"},"target_publication_id":{"type":"STRING","value":""},"target_publication_author_list":{"type":"LIST_STRING","value":["Skjerpen, Terje"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:RePEc:ssb:dispap:532"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Mathematics and natural science:Mathematics:Statistics:","Matematikk og naturvitenskap:Matematikk:Statistikk:","Engel elasticities","Non-parametric bootstrapping","Classical normal theory","Linear structural model","JEL classification: C13","JEL classification: C14","JEL classification: C15","JEL classification: C33","JEL classification: D12"]},"trust":{"type":"FLOAT","value":0.74632466},"target_publication_title":{"type":"STRING","value":"Engel elasticities, pseudo-maximum likelihood estimation and bootstrapped standard errors :a case study"},"provenance_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_dateofacceptance":{"type":"DATE","value":"2008-01-01"},"target_datasource_id":{"type":"STRING","value":"10|driver______::4dc196be332447baf11e431bd838e81c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:ssb:dispap:532\",\"titles\":[\"Engel elasticities, pseudo-maximum likelihood estimation and bootstrapped standard errors. A case study\"],\"abstracts\":[\"Estimation of standard errors of Engel elasticities within the framework of a linear structural model formulated on two-wave panel data is considered. The complete demand system is characterized by measurement errors in total expenditure and by latent preference variation. The estimation of the parameters as well as the standard errors of the estimates is based on the assumption that the variables are normally distributed. Considering a concrete case it is demonstrated that normality does not hold as a maintained assumption. In the light of this standard errors are estimated by means of bootstrapping. 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Les isotopes 90 et 89 du strontium peuvent être déterminés séparément en moins de 2 jours par un traitement rapide de l\\u0027échantillon et l\\u0027utilisation d\\u0027un détecteur à scintillation liquide.\"],\"language\":\"und\",\"subjects\":[\"[SDV:AEN] Life Sciences/Food and Nutrition\",\"[SDV:AEN] Sciences du Vivant/Alimentation et Nutrition\",\"[SDV:IDA] Life Sciences/Food engineering\",\"[SDV:IDA] Sciences du Vivant/Ingénierie des aliments\",\"radioactivity\",\"analytical method\",\"milk\\u003cbr\\u003e---\\u003cbr\\u003eStrontium\",\"radioactivité\",\"méthode d\\u0027analyse\",\"lait\"],\"creators\":[\"Brun, Stéphane\",\"Kergadallan, Yann\",\"Boursier, Bernadette\",\"Fremy, Jean-Marc\",\"Janin, Françoise\"],\"publicationdate\":\"2003-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1051/lait:2002046\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://hal.archives-ouvertes.fr/hal-00895347\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"},{\"url\":\"https://hal.archives-ouvertes.fr/hal-00895347\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00895347\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.archives-ouvertes.fr/hal-00895347\",\"id\":\"oai:HAL:hal-00895347v1\"},\"trust\":0.26515567}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:hal.archives-ouvertes.fr:hal-00895347"},"target_publication_author_list":{"type":"LIST_STRING","value":["Brun, Stéphane","Kergadallan, Yann","Boursier, Bernadette","Fremy, Jean-Marc","Janin, Françoise"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:hal-00895347v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[SDV:AEN] Life Sciences/Food and Nutrition","[SDV:AEN] Sciences du Vivant/Alimentation et Nutrition","[SDV:IDA] Life Sciences/Food engineering","[SDV:IDA] Sciences du Vivant/Ingénierie des aliments","radioactivity","analytical method","milk\u003cbr\u003e---\u003cbr\u003eStrontium","radioactivité","méthode d\u0027analyse","lait"]},"trust":{"type":"FLOAT","value":0.26515567},"target_publication_title":{"type":"STRING","value":"Methodology for determination of radiostrontium in milk: a review"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2003-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3111522\",\"titles\":[\"Clinical Outcome and Wound Healing following Carpal Tunnel Decompression: A Comparison of Two Common Suture Materials\"],\"abstracts\":[\"Introduction. Debate exists amongst surgeons regarding the ideal suture material for skin closure in carpal tunnel decompression (CTD). This study compares wound related complications, patient satisfaction, and functional outcome following open carpal tunnel decompression in patients undergoing wound closure with either of two common absorbable and nonabsorbable suture types. Materials and Methods. 53 patients underwent CTD with either 4/0 polypropylene (ProleneTM, n \\u003d 28) or 4/0 polyglactin (Vicryl RapideTM, n \\u003d 25) for skin closure. QuickDASH, VAS satisfaction scores, and Southampton wound scores were assessed preoperatively and at 2 and 6 weeks postoperatively. Results. At 6 weeks the mean QuickDASH scores postoperatively were 18.54 and 17.70 for absorbable and nonabsorbable sutures, respectively, (P \\u003d 0.86). The mean VAS scores were 0.61 and 0.42 (P \\u003d 0.91), respectively. All patients achieved a Southampton wound score of 0 by 6 weeks except one, who achieved 1C in the nonabsorbable group, equivalent to mild erythema. There were no complications in either group. Conclusion. Both suture types are safe and effective materials for CTD, and we recommend surgeons to choose according to personal preference, handling properties, and resources available for suture removal.\"],\"language\":\"eng\",\"subjects\":[\"Clinical Study\"],\"creators\":[\"Macfarlane, Robert J.\",\"Donnelly, Thomas D.\",\"Khan, Yousaf\",\"Morapudi, Syam\",\"Waseem, Mohammad\",\"Fischer, Jochen\"],\"publicationdate\":\"2014-08-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"BioMed Research International\",\"issn\":\"2314-6133\",\"eissn\":\"2314-6141\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2014/270137\",\"type\":\"doi\"},{\"value\":\"PMC4140113\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4140113\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2014/270137\",\"license\":\"OPEN\",\"hostedby\":\"BioMed Research International\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2014/270137\",\"license\":\"OPEN\",\"hostedby\":\"BioMed Research International\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2014/270137\",\"id\":\"oai:doaj.org/article:d60f9416b1c640bb87dcc3c55f8c6062\"},\"trust\":0.1711008}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3111522"},"target_publication_author_list":{"type":"LIST_STRING","value":["Macfarlane, Robert J.","Donnelly, Thomas D.","Khan, Yousaf","Morapudi, Syam","Waseem, Mohammad","Fischer, Jochen"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:d60f9416b1c640bb87dcc3c55f8c6062"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Clinical Study"]},"trust":{"type":"FLOAT","value":0.1711008},"target_publication_title":{"type":"STRING","value":"Clinical Outcome and Wound Healing following Carpal Tunnel Decompression: A Comparison of Two Common Suture Materials"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2014-08-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2359352\",\"titles\":[\"Alcohol and Cardiovascular Disease—Modulation of Vascular Cell Function\"],\"abstracts\":[\"Alcohol is a commonly used drug worldwide. Epidemiological studies have identified alcohol consumption as a factor that may either positively or negatively influence many diseases including cardiovascular disease, certain cancers and dementia. Often there seems to be a differential effect of various drinking patterns, with frequent moderate consumption of alcohol being salutary and binge drinking or chronic abuse being deleterious to one’s health. A better understanding of the cellular and molecular mechanisms mediating the many effects of alcohol consumption is beginning to emerge, as well as a clearer picture as to whether these effects are due to the direct actions of alcohol itself, or caused in part by its metabolites, e.g., acetaldehyde, or by incidental components present in the alcoholic beverage (e.g., polyphenols in red wine). This review will discuss evidence to date as to how alcohol (ethanol) might affect atherosclerosis that underlies cardiovascular and cerebrovascular disease, and the putative mechanisms involved, focusing on vascular endothelial and smooth muscle cell effects.\"],\"language\":\"eng\",\"subjects\":[\"Review\",\"alcohol\",\"ethanol\",\"cardiovascular\",\"atherosclerosis\",\"endothelial cell\",\"vascular smooth muscle\",\"signaling\",\"mechanisms\"],\"creators\":[\"Cahill, Paul A.\",\"Redmond, Eileen M.\"],\"publicationdate\":\"2012-04-01\",\"publisher\":\"MDPI\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Nutrients\",\"issn\":\"\",\"eissn\":\"2072-6643\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3390/nu4040297\",\"type\":\"doi\"},{\"value\":\"PMC3347010\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3347010\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.mdpi.com/2072-6643/4/4/297\",\"license\":\"OPEN\",\"hostedby\":\"Nutrients\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.mdpi.com/2072-6643/4/4/297\",\"license\":\"OPEN\",\"hostedby\":\"Nutrients\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.mdpi.com/2072-6643/4/4/297\",\"id\":\"oai:doaj.org/article:f7d96cc670194362bc7e0748ae2a9e86\"},\"trust\":0.16266137}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2359352"},"target_publication_author_list":{"type":"LIST_STRING","value":["Cahill, Paul A.","Redmond, Eileen M."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:f7d96cc670194362bc7e0748ae2a9e86"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Review","alcohol","ethanol","cardiovascular","atherosclerosis","endothelial cell","vascular smooth muscle","signaling","mechanisms"]},"trust":{"type":"FLOAT","value":0.16266137},"target_publication_title":{"type":"STRING","value":"Alcohol and Cardiovascular Disease—Modulation of Vascular Cell Function"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2012-04-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"\",\"titles\":[\"Prosjektorganisering i kommunal sektor :om forholdet mellom kontekstuelle variasjoner og prosjektutfall.\"],\"abstracts\":[\"Prosjektorganisering er en arbeidsform som representerer et alternativ til den tradisjonelle linjeorganisasjonen. Ved å avgrense oppgaver som skal utføres innenfor en spesiell tidsramme, er hensikten å øke organisasjoners evne til fornyelse. De siste tiårene har denne organisasjonsformen hatt en rask og omfattende spredning til ulike typer organisasjoner uavhengig av størrelse eller sektor. Avhandlingen dreier seg om kommunale utviklingsprosjekter, og er en kvalitativ og komparativ studie av tre prosjekter som er fulgt over en periode på tre år. Data er innhentet gjennom observasjoner, intervjuer, skriftlige kilder og lydopptak. Studien bidrar til innsikt i hva som skjer i praksis når aktører deltar i, og styrer, komplekse prosjektforløp i samhandling med omgivelsene. Dernest viser analysen hvilke forhold ved de tre prosjekteksemplene som kan bidra til å forstå variasjoner i prosjektforløp og -utfall. I studien anvendes ulike organisasjonsteoretiske perspektiver for å få frem sentrale kontekstuelle trekk ved de tre prosjektene. Studien viser at det var til dels store forskjeller mellom prosjektene med hensyn til forløp og opplevd resultat. I den komparative analysen ble det avdekket en rekke kritiske faktorer som påvirket utfall. Mulighetene for å lykkes ble langt på vei avgjort av prosjektenes grad av interne forankring og eksterne støtte i en tidlig fase av prosjektforløpet. Stikkord: Prosjektledelse, prosjektorganisering, kommunale utviklingsprosjekter, komparativ analyse\",\"Høgskolen i Harstad\"],\"language\":\"nor\",\"subjects\":[\"Social science:Political science and organizational theory:Public and private administration :\",\"Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:Offentlig og privat administrasjon :\",\"Social science:Political science and organizational theory:Public and private administration :\",\"Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:Offentlig og privat administrasjon :\",\"Social science:Political science and organizational theory:\",\"Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:\",\"Social science:Political science and organizational theory:\",\"Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:\",\"DOKTOR-001\"],\"creators\":[\"Hagebakken, Grete\"],\"publicationdate\":\"2012-01-01\",\"publisher\":\"University of Tromsø\",\"embargoenddate\":\"\",\"contributor\":[\"Røvik, Kjell Arne\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Norwegian Open Research Archives\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10037/4674\",\"license\":\"OPEN\",\"hostedby\":\"Norwegian Open Research Archives\",\"instancetype\":\"Doctoral thesis\"},{\"url\":\"http://hdl.handle.net/10037/4674\",\"license\":\"OPEN\",\"hostedby\":\"Munin - Open Research Archive\",\"instancetype\":\"Doctoral thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10037/4674\",\"license\":\"OPEN\",\"hostedby\":\"Munin - Open Research Archive\",\"instancetype\":\"Doctoral thesis\"}]},\"provenance\":{\"repositoryName\":\"Munin - Open Research Archive\",\"url\":\"http://hdl.handle.net/10037/4674\",\"id\":\"oai:www.ub.uit.no:10037/4674\"},\"trust\":0.9771998}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Norwegian Open Research Archives"},"target_publication_id":{"type":"STRING","value":""},"target_publication_author_list":{"type":"LIST_STRING","value":["Hagebakken, Grete"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:www.ub.uit.no:10037/4674"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::f47d0ad31c4c49061b9e505593e3db98"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Social science:Political science and organizational theory:Public and private administration :","Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:Offentlig og privat administrasjon :","Social science:Political science and organizational theory:Public and private administration :","Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:Offentlig og privat administrasjon :","Social science:Political science and organizational theory:","Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:","Social science:Political science and organizational theory:","Samfunnsvitenskap:Statsvitenskap og organisasjonsteori:","DOKTOR-001"]},"trust":{"type":"FLOAT","value":0.9771998},"target_publication_title":{"type":"STRING","value":"Prosjektorganisering i kommunal sektor :om forholdet mellom kontekstuelle variasjoner og prosjektutfall."},"provenance_datasource_name":{"type":"STRING","value":"Munin - Open Research Archive"},"target_dateofacceptance":{"type":"DATE","value":"2012-01-01"},"target_datasource_id":{"type":"STRING","value":"10|driver______::4dc196be332447baf11e431bd838e81c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:www.ub.uit.no:10037/4674\",\"titles\":[\"Prosjektorganisering i kommunal sektor : om forholdet mellom kontekstuelle variasjoner og prosjektutfall.\"],\"abstracts\":[\"Prosjektorganisering er en arbeidsform som representerer et alternativ til den tradisjonelle linjeorganisasjonen. 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Studien viser at det var til dels store forskjeller mellom prosjektene med hensyn til forløp og opplevd resultat. I den komparative analysen ble det avdekket en rekke kritiske faktorer som påvirket utfall. Mulighetene for å lykkes ble langt på vei avgjort av prosjektenes grad av interne forankring og eksterne støtte i en tidlig fase av prosjektforløpet.\\nStikkord: Prosjektledelse, prosjektorganisering, kommunale utviklingsprosjekter, komparativ analyse\",\"Høgskolen i Harstad\"],\"language\":\"und\",\"subjects\":[\"DOKTOR-001\",\"VDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240\",\"VDP::Social science: 200::Political science and organizational theory: 240\",\"VDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242\",\"VDP::Social science: 200::Political science and organizational theory: 240::Public and private administration: 242\"],\"creators\":[\"Hagebakken, Grete\"],\"publicationdate\":\"2012-12-13\",\"publisher\":\"University of Tromsø\",\"embargoenddate\":\"\",\"contributor\":[\"Røvik, Kjell Arne\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Munin - Open Research Archive\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10037/4674\",\"license\":\"OPEN\",\"hostedby\":\"Munin - Open Research Archive\",\"instancetype\":\"Doctoral thesis\"},{\"url\":\"http://hdl.handle.net/10037/4674\",\"license\":\"OPEN\",\"hostedby\":\"Norwegian Open Research Archives\",\"instancetype\":\"Doctoral thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10037/4674\",\"license\":\"OPEN\",\"hostedby\":\"Norwegian Open Research Archives\",\"instancetype\":\"Doctoral thesis\"}]},\"provenance\":{\"repositoryName\":\"Norwegian Open Research Archives\",\"url\":\"http://hdl.handle.net/10037/4674\",\"id\":\"\"},\"trust\":0.03276992}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Munin - Open Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:www.ub.uit.no:10037/4674"},"target_publication_author_list":{"type":"LIST_STRING","value":["Hagebakken, Grete"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::4dc196be332447baf11e431bd838e81c"},"target_publication_subject_list":{"type":"LIST_STRING","value":["DOKTOR-001","VDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240","VDP::Social science: 200::Political science and organizational theory: 240","VDP::Samfunnsvitenskap: 200::Statsvitenskap og organisasjonsteori: 240::Offentlig og privat administrasjon: 242","VDP::Social science: 200::Political science and organizational theory: 240::Public and private administration: 242"]},"trust":{"type":"FLOAT","value":0.03276992},"target_publication_title":{"type":"STRING","value":"Prosjektorganisering i kommunal sektor : om forholdet mellom kontekstuelle variasjoner og prosjektutfall."},"provenance_datasource_name":{"type":"STRING","value":"Norwegian Open Research Archives"},"target_dateofacceptance":{"type":"DATE","value":"2012-12-13"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::f47d0ad31c4c49061b9e505593e3db98"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:www.tara.tcd.ie:2262/51471\",\"titles\":[\"Null objects in second language acquisition: grammatical vs. performance models\"],\"abstracts\":[\"Abstract\\n Null direct objects provide a favourable testing ground for grammatical and performance models of argument omission. This article examines both types of models in order to determine which gives a more plausible account of the second language data. The data were collected from second language (L2) learners of Spanish by means of four oral production tasks and a grammaticality judgement task. The results reveal that null objects in oral production are rare events limited to pragmatically appropriate contexts, that is, when the referent is easily recoverable from preceding discourse. The results of the grammaticality judgement task indicate that beginning level learners frequently accept sentences containing null objects with specific antecedents, while more proficient learners categorically reject such argument omissions. It is suggested that lower proficiency learners may rely primarily on semantic strategies in parsing and evaluating sentences, while advanced learners are more sensitive to syntactic violations. A performance account is ultimately adopted to explain the data given the lack of a clear null object stage in development, the presence of self-corrections, and the discourse-constrained nature of object omissions.\"],\"language\":\"eng\",\"subjects\":[\"argument omission\",\"null objects\",\"direct object drop\",\"Spanish clitics\",\"anaphora\",\"grammaticality judgement tasks\"],\"creators\":[],\"publicationdate\":\"2008-01-01\",\"publisher\":\"Sage UK: London, England\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Trinity\\u0027s Access to Research Archive\"],\"pids\":[{\"value\":\"10.1177/0267658307082982\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://hdl.handle.net/2262/51471\",\"license\":\"OPEN\",\"hostedby\":\"Trinity\\u0027s Access to Research Archive\",\"instancetype\":\"\"},{\"url\":\"https://hal.archives-ouvertes.fr/hal-00570739\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00570739\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.archives-ouvertes.fr/hal-00570739\",\"id\":\"oai:HAL:hal-00570739v1\"},\"trust\":0.16951841}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Trinity\u0027s Access to Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:www.tara.tcd.ie:2262/51471"},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:hal-00570739v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["argument omission","null objects","direct object drop","Spanish clitics","anaphora","grammaticality judgement tasks"]},"trust":{"type":"FLOAT","value":0.16951841},"target_publication_title":{"type":"STRING","value":"Null objects in second language acquisition: grammatical vs. performance models"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2008-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::210f760a89db30aa72ca258a3483cc7f"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:hal-00570739v1\",\"titles\":[\"Null objects in second language acquisition: grammatical vs. performance models\"],\"abstracts\":[\"International audience\",\"Null direct objects provide a favourable testing ground for grammatical and performance models of argument omission. This article examines both types of models in order to determine which gives a more plausible account of the second language data. The data were collected from second language (L2) learners of Spanish by means of four oral production tasks and a grammaticality judgement task. The results reveal that null objects in oral production are rare events limited to pragmatically appropriate contexts, that is, when the referent is easily recoverable from preceding discourse. The results of the grammaticality judgement task indicate that beginning level learners frequently accept sentences containing null objects with specific antecedents, while more proficient learners categorically reject such argument omissions. It is suggested that lower proficiency learners may rely primarily on semantic strategies in parsing and evaluating sentences, while advanced learners are more sensitive to syntactic violations. A performance account is ultimately adopted to explain the data given the lack of a clear null object stage in development, the presence of self-corrections, and the discourse-constrained nature of object omissions.\"],\"language\":\"eng\",\"subjects\":[\"grammaticality judgement tasks\",\"argument omission\",\"null objects\",\"direct object drop\",\"Spanish clitics\",\"anaphora\"],\"creators\":[\"Zyzik, Eve C.\"],\"publicationdate\":\"2008-01-01\",\"publisher\":\"SAGE Publications (UK and US)\",\"embargoenddate\":\"\",\"contributor\":[\"Michigan State University ; Michigan State University\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1177/0267658307082982\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/hal-00570739\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://hdl.handle.net/2262/51471\",\"license\":\"OPEN\",\"hostedby\":\"Trinity\\u0027s Access to Research Archive\",\"instancetype\":\"\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/2262/51471\",\"license\":\"OPEN\",\"hostedby\":\"Trinity\\u0027s Access to Research Archive\",\"instancetype\":\"\"}]},\"provenance\":{\"repositoryName\":\"Trinity\\u0027s Access to Research Archive\",\"url\":\"http://hdl.handle.net/2262/51471\",\"id\":\"oai:www.tara.tcd.ie:2262/51471\"},\"trust\":0.4727224}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:hal-00570739v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Zyzik, Eve C."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:www.tara.tcd.ie:2262/51471"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::210f760a89db30aa72ca258a3483cc7f"},"target_publication_subject_list":{"type":"LIST_STRING","value":["grammaticality judgement tasks","argument omission","null objects","direct object drop","Spanish clitics","anaphora"]},"trust":{"type":"FLOAT","value":0.4727224},"target_publication_title":{"type":"STRING","value":"Null objects in second language acquisition: grammatical vs. performance models"},"provenance_datasource_name":{"type":"STRING","value":"Trinity\u0027s Access to Research Archive"},"target_dateofacceptance":{"type":"DATE","value":"2008-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:arXiv.org:1311.6209\",\"titles\":[\"Distributed Computation of Large-scale Graph Problems\"],\"abstracts\":[\" Motivated by the increasing need for fast distributed processing of\\nlarge-scale graphs such as the Web graph and various social networks, we study\\na message-passing distributed computing model for graph processing and present\\nlower bounds and algorithms for several graph problems. This work is inspired\\nby recent large-scale graph processing systems (e.g., Pregel and Giraph) which\\nare designed based on the message-passing model of distributed computing.\\n Our model consists of a point-to-point communication network of $k$ machines\\ninterconnected by bandwidth-restricted links. Communicating data between the\\nmachines is the costly operation (as opposed to local computation). The network\\nis used to process an arbitrary $n$-node input graph (typically $n \\\\gg k \\u003e 1$)\\nthat is randomly partitioned among the $k$ machines (a common implementation in\\nmany real world systems). Our goal is to study fundamental complexity bounds\\nfor solving graph problems in this model.\\n We present techniques for obtaining lower bounds on the distributed time\\ncomplexity. Our lower bounds develop and use new bounds in random-partition\\ncommunication complexity. We first show a lower bound of $\\\\Omega(n/k)$ rounds\\nfor computing a spanning tree (ST) of the input graph. This result also implies\\nthe same bound for other fundamental problems such as computing a minimum\\nspanning tree (MST). We also show an $\\\\Omega(n/k^2)$ lower bound for\\nconnectivity, ST verification and other related problems.\\n We give algorithms for various fundamental graph problems in our model. We\\nshow that problems such as PageRank, MST, connectivity, and graph covering can\\nbe solved in $\\\\tilde{O}(n/k)$ time, whereas for shortest paths, we present\\nalgorithms that run in $\\\\tilde{O}(n/\\\\sqrt{k})$ time (for $(1+\\\\epsilon)$-factor\\napprox.) and in $\\\\tilde{O}(n/k)$ time (for $O(\\\\log n)$-factor approx.)\\nrespectively.\\n\",\"Comment: In Proceedings of SODA 2015\"],\"language\":\"eng\",\"subjects\":[\"Computer Science - Distributed, Parallel, and Cluster Computing\",\"Computer Science - Data Structures and Algorithms\",\"C.2.4\",\"F.1.1\"],\"creators\":[\"Klauck, Hartmut\",\"Nanongkai, Danupon\",\"Pandurangan, Gopal\",\"Robinson, Peter\"],\"publicationdate\":\"2013-11-25\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"arXiv.org e-Print Archive\"],\"pids\":[],\"instances\":[{\"url\":\"http://arxiv.org/abs/1311.6209\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"},{\"url\":\"http://urn.kb.se/resolve?urn\\u003durn:nbn:se:kth:diva-165842\",\"license\":\"OPEN\",\"hostedby\":\"Publikationer från KTH\",\"instancetype\":\"Conference object\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://urn.kb.se/resolve?urn\\u003durn:nbn:se:kth:diva-165842\",\"license\":\"OPEN\",\"hostedby\":\"Publikationer från KTH\",\"instancetype\":\"Conference object\"}]},\"provenance\":{\"repositoryName\":\"Publikationer från KTH\",\"url\":\"http://urn.kb.se/resolve?urn\\u003durn:nbn:se:kth:diva-165842\",\"id\":\"oai:DiVA.org:kth-165842\"},\"trust\":0.1214633}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_publication_id":{"type":"STRING","value":"oai:arXiv.org:1311.6209"},"target_publication_author_list":{"type":"LIST_STRING","value":["Klauck, Hartmut","Nanongkai, Danupon","Pandurangan, Gopal","Robinson, Peter"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:DiVA.org:kth-165842"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::a4f23670e1833f3fdb077ca70bbd5d66"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Computer Science - Distributed, Parallel, and Cluster Computing","Computer Science - Data Structures and Algorithms","C.2.4","F.1.1"]},"trust":{"type":"FLOAT","value":0.1214633},"target_publication_title":{"type":"STRING","value":"Distributed Computation of Large-scale Graph Problems"},"provenance_datasource_name":{"type":"STRING","value":"Publikationer från KTH"},"target_dateofacceptance":{"type":"DATE","value":"2013-11-25"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:DiVA.org:kth-165842\",\"titles\":[\"Distributed Computation of Large-scale Graph Problems\"],\"abstracts\":[\"Motivated by the increasing need for fast distributed processing of large-scale graphs such as the Web graph and various social networks, we study a number of fundamental graph problems in the message-passing model, where we have k machines that jointly perform computation on an arbitrary n-node (typically, n ≫ k) input graph. The graph is assumed to be randomly partitioned among the k ≥ 2 machines (a common implementation in many real world systems). The communication is point-to-point, and the goal is to minimize the time complexity i.e., the number of communication rounds, of solving various fundamental graph problems. We present lower bounds that quantify the fundamental time limitations of distributively solving graph problems. We first show a lower bound of Ω(n/k) rounds for computing a spanning tree (ST) of the input graph. This result also implies the same bound for other fundamental problems such as computing a minimum spanning tree (MST), breadth-first tree (BFS), and shortest paths tree (SPT). We also show an Ω(n/k2) lower bound for connectivity ST verification and other related problems. Our lower bounds develop and use new bounds in random-partition communication complexity. To complement our lower bounds, we also give algorithms for various fundamental graph problems, e.g., PageRank, MST, connectivity, ST verification, shortest paths, cuts, spanners, covering problems, densest subgraph, subgraph isomorphism, finding triangles, etc. We show that problems such as PageRank, MST, connectivity, and graph covering can be solved in Õ(n/k) time (the notation Õ hides polylog(n) factors and an additive polylog(n) term); this shows that one can achieve almost linear (in k) speedup, whereas for shortest paths, we present algorithms that run in Õ(n/Ok) time (for (1 + ε)-factor approximation) and in Õ(n/k) time (for O(log n)-factor approximation) respectively. Our results are a step towards understanding the complexity of distributively solving large-scale graph problems. \",\"\\u003cp\\u003eQC 20150520\\u003c/p\\u003e\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Klauck, Hartmut\",\"Na Nongkai, Danupon\",\"Pandurangan, Gopal\",\"Robinson, Peter\"],\"publicationdate\":\"2015-01-01\",\"publisher\":\"National University of Singapore\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Publikationer från KTH\"],\"pids\":[],\"instances\":[{\"url\":\"http://urn.kb.se/resolve?urn\\u003durn:nbn:se:kth:diva-165842\",\"license\":\"OPEN\",\"hostedby\":\"Publikationer från KTH\",\"instancetype\":\"Conference object\"},{\"url\":\"http://arxiv.org/abs/1311.6209\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print 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document\\u003c/P\\u003e\\n\\u003cP\\u003e© University of Pretoria 2002\\u003c/P\\u003e\\n\\u003cP\\u003e\\u003cU\\u003ePlease cite as follows\\u003c/U\\u003e:\\u003cP\\u003e\\nDu Plessis, PJ 2002, \\u003cI\\u003e \\u0027n Ondersoek na die rol van die skoolhoof as veranderingsagent in finansiële skoolbestuur \\u003c/I\\u003e, DPhil thesis, University of Pretoria, Pretoria, viewed \\u003cI\\u003eyymmdd\\u003c/I\\u003e \\u003chttp://upetd.up.ac.za/thesis/available/etd- 11042005-110013/\\u003e\\n\\u003cP\\u003eH 98/th\\u003c/P\\u003e\\n\"],\"language\":\"und\",\"subjects\":[\"Education Management and Policy Studies\"],\"creators\":[\"Du Plessis, Petrus Jacobus\"],\"publicationdate\":\"2005-11-07\",\"publisher\":\"University of Pretoria\",\"embargoenddate\":\"\",\"contributor\":[\"Dr J J Conradie\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"University of Pretoria Electronic Theses and 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{"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:repository.up.ac.za:2263/29222\",\"titles\":[\"\\u0027n Ondersoek na die rol van die skoolhoof as veranderingsagent in finansiële skoolbestuur (Afrikaans)\"],\"abstracts\":[\"Please read the abstract in the section 00front of this document\"],\"language\":\"und\",\"subjects\":[\"School principals south africa\",\"Resource allocation\",\"School management and organization south africa\",\"School budgets south africa\"],\"creators\":[\"Du Plessis, Petrus Jacobus\"],\"publicationdate\":\"2002-12-31\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"UPSpace at the University of Pretoria\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/2263/29222\",\"license\":\"OPEN\",\"hostedby\":\"UPSpace at the University of 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{"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2576910\",\"titles\":[\"Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease\"],\"abstracts\":[\"Huntington disease (HD) is a devastating, late-onset, inherited neurodegenerative disorder that manifests with personality changes, movement disorders, and cognitive decline. It is caused by a CAG repeat expansion in exon 1 of the HTT gene that translates to a polyglutamine tract in the huntingtin protein (HTT). The formation of HTT fragments has been implicated as an essential step in the molecular pathogenesis of HD and several proteases that cleave HTT have been identified. However, the importance of smaller N-terminal fragments has been highlighted by their presence in HD postmortem brains and by the fact that nuclear inclusions are only detected by antibodies to the N terminus of HTT. Despite an intense research effort, the precise length of these fragments and the mechanism by which they are generated remains unknown. Here we show that CAG repeat length–dependent aberrant splicing of exon 1 HTT results in a short polyadenylated mRNA that is translated into an exon 1 HTT protein. Given that mutant exon 1 HTT proteins have consistently been shown to be highly pathogenic in HD mouse models, the aberrant splicing of HTT mRNA provides a mechanistic basis for the molecular pathogenesis of HD. RNA-targeted therapeutic strategies designed to lower the levels of HTT are under development. Many of these approaches would not prevent the production of exon 1 HTT and should be reviewed in light of our findings.\"],\"language\":\"eng\",\"subjects\":[\"Biological Sciences\"],\"creators\":[\"Sathasivam, Kirupa\",\"Neueder, Andreas\",\"Gipson, Theresa A.\",\"Landles, Christian\",\"Benjamin, Agnesska C.\",\"Bondulich, Marie K.\",\"Smith, Donna L.\",\"Faull, Richard L. M.\",\"Roos, Raymund A. 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C.","Howland, David"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:dspace.mit.edu:1721.1/80388"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::2a38a4a9316c49e5a833517c45d31070"},"trust":{"type":"FLOAT","value":0.17703903},"target_publication_title":{"type":"STRING","value":"Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease"},"provenance_datasource_name":{"type":"STRING","value":"DSpace@MIT"},"target_dateofacceptance":{"type":"DATE","value":"2012-12-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::2a38a4a9316c49e5a833517c45d31070"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:nax:conyad:v:59:y:2014:i:4:p:87-104\",\"titles\":[\"Performance of the different RAROC models and their relation with the creation of economic value: A study of the largest banks operating in Brazil\"],\"abstracts\":[\"This article approaches several different methodologies for calculation of the RAROC (Risk Adjusted Return on Capital) for Brazilian banks. Two questions gave reason to the study:whether the application of different methods for calculation of the RAROC would generate significantly different results?, and checking what is the connection between the RAROC and the generation of economic value, measured by the EVA (Economic Value Added), for the largest banks with operations in Brazil? The following methodologies for verification of the RAROC were applied: Buch’s Method (2011); Prokopczuk’s Method (2006); Prokopczuk’s Method (2006) with application of the VaR technique; Saunders’s Method (2007); Chapelle’s Method (2008); and the Smithon \\u0026 Hayt Method (2001), by applying these parametric and non-parametric statistics in order to check the sensibility of the differences between models. This study has evidenced that, when we compare the methodology based on minimum capital with other methodologies, there are no significant differences, except in the few cases indicated. It is important to notice it only occurred in the case of the Bank of Brazil and it was concentrated in the comparison of the Creditmetrics models and in the methodology in which there is equivalence by the reference equity.\"],\"language\":\"und\",\"subjects\":[\"EVA (Economic Value Added), RAROC (Risk Adjusted Return on Capital), risk capital, banking, Basel accords\"],\"creators\":[\"Guasti Lima Fabiano\",\"Castro Junior Sant Clair de\",\"Pimenta Júnior Tabajara\",\"Gaio Luiz Eduardo\"],\"publicationdate\":\"2014-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Contaduría y Administración\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Research Papers in Economics\"],\"pids\":[],\"instances\":[{\"url\":\"http://www.revistas.unam.mx/index.php/rca/article/viewFile/49420/pdf_12\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Article\"},{\"url\":\"http://www.redalyc.org/articulo.oa?id\\u003d39531859005\",\"license\":\"OPEN\",\"hostedby\":\"Contaduría y Administración\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.redalyc.org/articulo.oa?id\\u003d39531859005\",\"license\":\"OPEN\",\"hostedby\":\"Contaduría y Administración\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.redalyc.org/articulo.oa?id\\u003d39531859005\",\"id\":\"oai:doaj.org/article:68d5dc7835604b0fab9080aa1c1d0f3f\"},\"trust\":0.31062847}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_publication_id":{"type":"STRING","value":"oai:RePEc:nax:conyad:v:59:y:2014:i:4:p:87-104"},"target_publication_author_list":{"type":"LIST_STRING","value":["Guasti Lima Fabiano","Castro Junior Sant Clair de","Pimenta Júnior Tabajara","Gaio Luiz Eduardo"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:68d5dc7835604b0fab9080aa1c1d0f3f"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["EVA (Economic Value Added), RAROC (Risk Adjusted Return on Capital), risk capital, banking, Basel accords"]},"trust":{"type":"FLOAT","value":0.31062847},"target_publication_title":{"type":"STRING","value":"Performance of the different RAROC models and their relation with the creation of economic value: A study of the largest banks operating in Brazil"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2014-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:run.unl.pt:10362/13743\",\"titles\":[\"Desafios da arte contemporânea à conservação e restauro. Documentar a arte Portuguesa dos anos 60/70\"],\"abstracts\":[\"A dissertação que aqui se apresenta partiu da necessidade de colocar em confronto as bases éticas da conservação e restauro, que assentam na defesa da materialidade histórica, com a progressiva desmaterialização da arte que ocorre a partir da década de 60 em diante. A\\norganização do trabalho implicou, na escrita, a distinção entre duas partes: uma históricoteórica e a outra de carácter mais prático. Na primeira parte procurámos justificar a progressiva tendência histórica para a desmaterialização do suporte artístico bem como a consequente necessidade de um re-pensamento dos aspectos éticos e práticos da conservação, com particular atenção à documentação do ponto de vista autoral. Na segunda parte da dissertação apresentamos um conjunto de oito casos práticos, a partir de obras de oito artistas portugueses – Henrique Ruivo, Lourdes Castro, Noronha da Costa, Ana Vieira, Alberto Carneiro, João Vieira, René Bertholo e Helena Almeida - todos com início de\\ncarreira na década de 60. Procurámos reunir, com base numa investigação em torno dos\\naspectos da criação da obra, mas também da sua recepção, informação detalhada sobre\\nmateriais constitutivos, sua origem e semântica, técnicas, processos criativos, bem como a posição de cada autor relativamente ao envelhecimento das obras em análise. Para o efeito procedemos a um conjunto de entrevistas presenciais aos artistas em questão, directores de museus e curadores – com envolvimento com as obras daqueles - bem como ao levantamento da fortuna crítica associada às obras seleccionadas. Um dos aspectos que se\\nrevelou decisivo ao longo do trabalho foi o da investigação dos processos criativos, central para obras cuja autenticidade não se pode resumir a qualquer noção de originalidade material, podendo contudo ser alicerçada na investigação e documentação do processo criativo, realizado essencialmente a partir do ponto de vista autoral. O trabalho efectuado teve também como objectivo a compreensão das condições reais de conservação documental das peças. Concluímos: a necessidade de se proceder à documentação(inscrição) como forma de conservação; o papel imprescindível de uma historiografia da arte mais centrada nos aspectos da preservação; a urgência de formar profissionais preparados para desempenhar esta tarefa; bem como a indispensabilidade de ferramentas que permitam a organização da informação e a sua disponibilização, no âmbito da comunidade envolvida na arte contemporânea, e ao público em geral.\"],\"language\":\"por\",\"subjects\":[],\"creators\":[\"Macedo, Rita\"],\"publicationdate\":\"2008-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[\"Silva, Raquel\",\"Seruya, Ana Isabel\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Repositório da Universidade Nova de Lisboa\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10362/13743\",\"license\":\"OPEN\",\"hostedby\":\"Repositório da Universidade Nova de Lisboa\",\"instancetype\":\"Master thesis\"},{\"url\":\"http://hdl.handle.net/10362/13144\",\"license\":\"OPEN\",\"hostedby\":\"Repositório da Universidade Nova de Lisboa\",\"instancetype\":\"Doctoral thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10362/13144\",\"license\":\"OPEN\",\"hostedby\":\"Repositório da Universidade Nova de Lisboa\",\"instancetype\":\"Doctoral thesis\"}]},\"provenance\":{\"repositoryName\":\"Repositório da Universidade Nova de Lisboa\",\"url\":\"http://hdl.handle.net/10362/13144\",\"id\":\"oai:run.unl.pt:10362/13144\"},\"trust\":0.17481434}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Repositório da Universidade Nova de Lisboa"},"target_publication_id":{"type":"STRING","value":"oai:run.unl.pt:10362/13743"},"target_publication_author_list":{"type":"LIST_STRING","value":["Macedo, Rita"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:run.unl.pt:10362/13144"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::a8f8f60264024dca151f164729b76c0b"},"trust":{"type":"FLOAT","value":0.17481434},"target_publication_title":{"type":"STRING","value":"Desafios da arte contemporânea à conservação e restauro. Documentar a arte Portuguesa dos anos 60/70"},"provenance_datasource_name":{"type":"STRING","value":"Repositório da Universidade Nova de Lisboa"},"target_dateofacceptance":{"type":"DATE","value":"2008-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::a8f8f60264024dca151f164729b76c0b"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:run.unl.pt:10362/13144\",\"titles\":[\"Desafios da arte contemporânea à conservação e restauro documentar a arte portuguesa dos Anos 60/70\"],\"abstracts\":[\"Dissertação para obtenção do Grau de Doutor em Conservação e Restauro, ramo de Teoria, História e Técnicas da Produção Artística\",\"A dissertação que aqui se apresenta partiu da necessidade de colocar em confronto as bases\\néticas da conservação e restauro, que assentam na defesa da materialidade histórica, com a\\nprogressiva desmaterialização da arte que ocorre a partir da década de 60 em diante. 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Procurámos reunir, com base numa investigação em torno dos\\naspectos da criação da obra, mas também da sua recepção, informação detalhada sobre\\nmateriais constitutivos, sua origem e semântica, técnicas, processos criativos, bem como a\\nposição de cada autor relativamente ao envelhecimento das obras em análise. Para o efeito\\nprocedemos a um conjunto de entrevistas presenciais aos artistas em questão, directores de\\nmuseus e curadores – com envolvimento com as obras daqueles - bem como ao\\nlevantamento da fortuna crítica associada às obras seleccionadas. Um dos aspectos que se\\nrevelou decisivo ao longo do trabalho foi o da investigação dos processos criativos, central\\npara obras cuja autenticidade não se pode resumir a qualquer noção de originalidade\\nmaterial, podendo contudo ser alicerçada na investigação e documentação do processo\\ncriativo, realizado essencialmente a partir do ponto de vista autoral. O trabalho efectuado\\nteve também como objectivo a compreensão das condições reais de conservação\\ndocumental das peças. Concluímos: a necessidade de se proceder à documentação\\n(inscrição) como forma de conservação; o papel imprescindível de uma historiografia da\\narte mais centrada nos aspectos da preservação; a urgência de formar profissionais\\npreparados para desempenhar esta tarefa; bem como a indispensabilidade de ferramentas\\nque permitam a organização da informação e a sua disponibilização, no âmbito da\\ncomunidade envolvida na arte contemporânea, e ao público em geral.\"],\"language\":\"por\",\"subjects\":[],\"creators\":[\"Macedo, Rita\"],\"publicationdate\":\"2008-01-01\",\"publisher\":\"Faculdade de Ciencias e Tecnologia\",\"embargoenddate\":\"\",\"contributor\":[\"Silva, Raquel\",\"Seruya, Ana Isabel\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Repositório da Universidade Nova de Lisboa\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10362/13144\",\"license\":\"OPEN\",\"hostedby\":\"Repositório da Universidade Nova de Lisboa\",\"instancetype\":\"Doctoral thesis\"},{\"url\":\"http://hdl.handle.net/10362/13743\",\"license\":\"OPEN\",\"hostedby\":\"Repositório da Universidade Nova de Lisboa\",\"instancetype\":\"Master thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10362/13743\",\"license\":\"OPEN\",\"hostedby\":\"Repositório da Universidade Nova de Lisboa\",\"instancetype\":\"Master thesis\"}]},\"provenance\":{\"repositoryName\":\"Repositório da Universidade Nova de Lisboa\",\"url\":\"http://hdl.handle.net/10362/13743\",\"id\":\"oai:run.unl.pt:10362/13743\"},\"trust\":0.47693932}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Repositório da Universidade Nova de Lisboa"},"target_publication_id":{"type":"STRING","value":"oai:run.unl.pt:10362/13144"},"target_publication_author_list":{"type":"LIST_STRING","value":["Macedo, Rita"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:run.unl.pt:10362/13743"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::a8f8f60264024dca151f164729b76c0b"},"trust":{"type":"FLOAT","value":0.47693932},"target_publication_title":{"type":"STRING","value":"Desafios da arte contemporânea à conservação e restauro documentar a arte portuguesa dos Anos 60/70"},"provenance_datasource_name":{"type":"STRING","value":"Repositório da Universidade Nova de Lisboa"},"target_dateofacceptance":{"type":"DATE","value":"2008-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::a8f8f60264024dca151f164729b76c0b"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:doc.utwente.nl:58041\",\"titles\":[\"Gas assisted mechanical expression of oilseeds\"],\"abstracts\":[\"It is the objective of this thesis to show the general applicability of the Gas Assisted Mechanical Expression (GAME) process for recovery of oil from oilseeds with high yields. In this process, the oilseeds are saturated with supercritical CO2 before mechanical pressing. The CO2 displaces part of the oil during the pressing and therefore increases the oil yield. To prove the general applicability of GAME, a number of oilseeds with a wide range of properties was chosen: sesame, linseed, jatropha, palm kernel and rapeseed. These seeds all produce high added value oils with a low market volume and their properties range from soft (sesame) to hard (jatropha, palm kernel) and from high (sesame) to low oil contents (palm kernel). A lab scale hydraulic press was used to determine the oil yields and expression rates that can be obtained for both conventional expression and GAME expression under a wide range of process conditions.\"],\"language\":\"und\",\"subjects\":[],\"creators\":[\"Willems, Paul\"],\"publicationdate\":\"2007-01-01\",\"publisher\":\"University of Twente\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Universiteit Twente Repository\"],\"pids\":[],\"instances\":[{\"url\":\"http://purl.utwente.nl/publications/58041\",\"license\":\"OPEN\",\"hostedby\":\"Universiteit Twente Repository\",\"instancetype\":\"Doctoral thesis\"},{\"url\":\"http://purl.utwente.nl/publications/58041\",\"license\":\"OPEN\",\"hostedby\":\"Universiteit Twente Repository\",\"instancetype\":\"Doctoral thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://purl.utwente.nl/publications/58041\",\"license\":\"OPEN\",\"hostedby\":\"Universiteit Twente Repository\",\"instancetype\":\"Doctoral thesis\"}]},\"provenance\":{\"repositoryName\":\"NARCIS\",\"url\":\"http://purl.utwente.nl/publications/58041\",\"id\":\"ut:oai:doc.utwente.nl:58041\"},\"trust\":0.82453346}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Universiteit Twente Repository"},"target_publication_id":{"type":"STRING","value":"oai:doc.utwente.nl:58041"},"target_publication_author_list":{"type":"LIST_STRING","value":["Willems, Paul"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["ut:oai:doc.utwente.nl:58041"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::fdb035c8b3e0540a8d9a561a6c44f4de"},"trust":{"type":"FLOAT","value":0.82453346},"target_publication_title":{"type":"STRING","value":"Gas assisted mechanical expression of oilseeds"},"provenance_datasource_name":{"type":"STRING","value":"NARCIS"},"target_dateofacceptance":{"type":"DATE","value":"2007-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8dd48d6a2e2cad213179a3992c0be53c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:http://gredos.usal.es/jspui:10366/70453\",\"titles\":[\"Las pinturas alpestres de la Penya de l\\u0027Ermita del Vicari (Altea, Alicante)\"],\"abstracts\":[\"[ES] La zona central mediterránea de la Península Ibérica cuenta con un nuevo descubrimiento de Arte Rupestre Postpaleolítico en su versión esquemática. Las manifestaciones pintadas se revelan de gran interés al existir representaciones antropomorfas bitriangulares y oculadas, desconocidas en las variantes tipológicas al uso, asociadas a soliformes, zigzags, puntiformes y grupos de barras paralelas. La complejidad compositiva y figurativa, con un fuerte componente simbólico, indican la existencia de creencias difícilmente comprensibles desde nuestros conocimientos actuales. En los últimos años, este arte se fecha a partir del V milenio a.C. hasta el II milenio a.C, según los paralelos muebles del contexto arqueológico.\",\"[EN] A new discovery in Post Paleolithic Schematic Rock Art has been made in the central Mediterranean zone of the Iberian Peninsula. The Paintings are very interesting due to the presence of bitriangular anthropomorphic representations and idols, unknown before in typologies, usually associated to sunforms, zigzags, dots and groups of paralells bars. The complexity in figuration and composition and the strong symbolic component show the existence of beliefs not easily understandable with our present knowledge. In the present state of research this art is dated from the V millennium BC to the II millennium BC on the basis of comparisons with mobiliary art from an archeological context.\"],\"language\":\"esl/spa\",\"subjects\":[\"Prehistoria\",\"Arqueología\",\"Prehistory\",\"Archaeology\"],\"creators\":[\"Galiana Botella, María Francia\",\"Torregrosa Giménez, Palmira\"],\"publicationdate\":\"2009-12-11\",\"publisher\":\"Ediciones Universidad de Salamanca (España)\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"GREDOS\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10366/70453\",\"license\":\"OPEN\",\"hostedby\":\"GREDOS\",\"instancetype\":\"Article\"},{\"url\":\"http://revistas.usal.es/index.php/0514-7336/article/view/5074\",\"license\":\"OPEN\",\"hostedby\":\"Zephyrus\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://revistas.usal.es/index.php/0514-7336/article/view/5074\",\"license\":\"OPEN\",\"hostedby\":\"Zephyrus\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://revistas.usal.es/index.php/0514-7336/article/view/5074\",\"id\":\"oai:doaj.org/article:37331a39372c46afafadfdd06d44be63\"},\"trust\":0.54255795}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"GREDOS"},"target_publication_id":{"type":"STRING","value":"oai:http://gredos.usal.es/jspui:10366/70453"},"target_publication_author_list":{"type":"LIST_STRING","value":["Galiana Botella, María Francia","Torregrosa Giménez, Palmira"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:37331a39372c46afafadfdd06d44be63"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Prehistoria","Arqueología","Prehistory","Archaeology"]},"trust":{"type":"FLOAT","value":0.54255795},"target_publication_title":{"type":"STRING","value":"Las pinturas alpestres de la Penya de l\u0027Ermita del Vicari (Altea, Alicante)"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2009-12-11"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::daa96d9681a21445772454cbddf0cac1"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2956031\",\"titles\":[\"Multistage Fragmentation of Ion Trap Mass Spectrometry System and Pseudo-MS3 of Triple Quadrupole Mass Spectrometry Characterize Certain (E)-3-(Dimethylamino)-1-arylprop-2-en-1-ones: A Comparative Study\"],\"abstracts\":[\"A new approach was recently introduced to improve the structure elucidation power of tandem mass spectrometry simulating the MS3 of ion trap mass spectrometry system overcoming the different drawbacks of the latter. The fact that collision induced dissociation in the triple quadrupole mass spectrometer system provides richer fragment ions compared to those achieved in the ion trap mass spectrometer system utilizing resonance excitation. Moreover, extracting comprehensive spectra in the ion trap needs multistage fragmentation, whereas similar fragment ions may be acquired from one stage product ion scan using the triple quadrupole mass spectrometer. The new strategy was proven to enhance the qualitative performance of tandem mass spectrometry for structural elucidation of different chemical entities. In the current study we are endeavoring to prove our hypothesis of the efficiency of the new pseudo-MS3 technique via its comparison with the MS3 mode of ion trap mass spectrometry system. Ten pharmacologically and synthetically important (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones (enaminones 4a–j) were chosen as model compounds for this study. 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PMD results from deletion, mutation, or duplication of the proteolipid protein gene (PLP1) located at Xq22, leading to the failure of axon myelination by oligodendrocytes in the central nervous system. PMD may be suspected when there are clinical manifestations such as nystagmus, developmental delays, and spasticity, and genetic analysis can confirm the diagnosis. Further diagnostic manifestations of the disease include a lack of myelination on brain magnetic resonance (MR) imaging and aberrant N-acetyl aspartate (NAA) and choline concentrations that reflect axonal and myelination abnormalities on phroton MR spectroscopy. We report 5 cases of PMD (in 1 girl and 4 boys). PLP1 duplication was detected in 2 patients. Brain MR analyses and MR spectroscopy were performed for all the patients. The brain MR images showed white matter abnormalities typical of PMD, and the MR spectroscopic images showed diverse patterns of NAA, creatinine, and choline concentrations. 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La mission d\\u0027un satellite d\\u0027observation est d\\u0027obtenir des photographies de la surface de la Terre afin de satisfaire des requêtes d\\u0027utilisateurs. Les demandes, émanant de différents utilisateurs, doivent faire l\\u0027objet d\\u0027un traitement avant transmission d\\u0027un ordre vers le satellite, correspondant à une séquence d\\u0027acquisitions sélectionnées. Cette séquence doit optimiser deux objectifs sous contraintes d\\u0027exploitation. Le premier objectif est de maximiser le profit global des acquisitions sélectionnées. Le second est d\\u0027assurer l\\u0027équité du partage des ressources en minimisant la différence maximale de profit entre les utilisateurs. Deux métaheuristiques, composées d\\u0027un algorithme génétique à clé aléatoire biaisées (biased random key genetic algorithm - BRKGA) et d\\u0027une recherche locale multi-objectif basée sur des indicateurs (indicator based multi-objective local search - IBMOLS), sont proposées pour résoudre le problème. Pour BRKGA, trois méthodes de sélection, empruntées à NSGA-II, SMS-EMOA, et IBEA, sont proposées pour choisir un ensemble de chromosomes préférés comme ensemble élite. Trois stratégies de décodage, parmi lesquelles deux sont des décodages uniques et la dernière un décodage hybride, sont appliquées pour décoder les chromosomes afin d\\u0027obtenir des solutions. Pour IBMOLS, plusieurs méthodes pour générer la population initiale sont testées et une structure de voisinage est également proposée. Des expériences sont menées sur des cas réalistes, issus d\\u0027instances modifiées du challenge ROADEF 2003. On obtient ainsi les fronts de Pareto approximés de BRKGA et IBMOLS dont on calcule les hypervolumes. Les résultats de ces deux algorithmes sont comparés.\"],\"language\":\"eng\",\"subjects\":[\"[INFO:INFO_RO] Computer Science/Operations Research\",\"[INFO:INFO_RO] Informatique/Recherche opérationnelle\",\"Recherche opérationnelle\",\"Optimisation combinatoire\",\"Optimisation multi-objectif\",\"Metaheuristiques\",\"Images satellite\",\"Planification\"],\"creators\":[\"Tangpattanakul, Panwadee\"],\"publicationdate\":\"2013-09-26\",\"publisher\":\"INSA de Toulouse\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"http://tel.archives-ouvertes.fr/tel-00903756\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Doctoral thesis\"},{\"url\":\"https://tel.archives-ouvertes.fr/tel-00903756\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://tel.archives-ouvertes.fr/tel-00903756\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://tel.archives-ouvertes.fr/tel-00903756\",\"id\":\"oai:HAL:tel-00903756v1\"},\"trust\":0.63137925}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:tel.archives-ouvertes.fr:tel-00903756"},"target_publication_author_list":{"type":"LIST_STRING","value":["Tangpattanakul, Panwadee"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:tel-00903756v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[INFO:INFO_RO] Computer Science/Operations Research","[INFO:INFO_RO] Informatique/Recherche opérationnelle","Recherche opérationnelle","Optimisation combinatoire","Optimisation multi-objectif","Metaheuristiques","Images satellite","Planification"]},"trust":{"type":"FLOAT","value":0.63137925},"target_publication_title":{"type":"STRING","value":"Optimisation multi-objectif de missions de satellites d\u0027observation de la Terre"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2013-09-26"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:tel-00903756v1\",\"titles\":[\"Optimisation multi-objectif de missions de satellites d\\u0027observation de la Terre\"],\"abstracts\":[\"This thesis considers the selection and scheduling problem of observations for agile Earth observing satellites. The mission of Earth observing satellites is to obtain photographs of the Earth surface to satisfy user requirements. Requests from several users have to be managed before transmitting an order, which is a sequence of selected acquisitions, to the satellite. The obtained sequence must optimize two objectives under operation constraints. The first objective is to maximize the total profit of the selected acquisitions. The second one is to ensure the fairness of resource sharing by minimizing the maximum profit difference between users. Two metaheuristic algorithms, consisting of a biased random key genetic algorithm (BRKGA) and an indicator-based multi-objective local search (IBMOLS), are proposed to solve the problem. For BRKGA, three selection methods, borrowed from NSGA-II, SMS-EMOA, and IBEA, are proposed to select a set of preferred chromosomes to be the elite set. Three decoding strategies, which are two single decoding and a hybrid decoding, are applied to decode chromosomes to become solutions. For IBMOLS, several methods for generating the initial population are tested and the neighborhood structure according to the problem is also proposed. Experiments are conducted on realistic instances based on ROADEF 2003 challenge instances. Hypervolumes of the approximate Pareto fronts are computed and the results from the two algorithms are compared.\",\"Cette thèse considère le problème de sélection et d\\u0027ordonnancement des prises de vue d\\u0027un satellite agile d\\u0027observation de la Terre. La mission d\\u0027un satellite d\\u0027observation est d\\u0027obtenir des photographies de la surface de la Terre afin de satisfaire des requêtes d\\u0027utilisateurs. Les demandes, émanant de différents utilisateurs, doivent faire l\\u0027objet d\\u0027un traitement avant transmission d\\u0027un ordre vers le satellite, correspondant à une séquence d\\u0027acquisitions sélectionnées. Cette séquence doit optimiser deux objectifs sous contraintes d\\u0027exploitation. Le premier objectif est de maximiser le profit global des acquisitions sélectionnées. Le second est d\\u0027assurer l\\u0027équité du partage des ressources en minimisant la différence maximale de profit entre les utilisateurs. Deux métaheuristiques, composées d\\u0027un algorithme génétique à clé aléatoire biaisées (biased random key genetic algorithm - BRKGA) et d\\u0027une recherche locale multi-objectif basée sur des indicateurs (indicator based multi-objective local search - IBMOLS), sont proposées pour résoudre le problème. 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Les résultats de ces deux algorithmes sont comparés.\"],\"language\":\"eng\",\"subjects\":[\"Satellite Images\",\"Planning\",\"Multi-objective optimization\",\"Metaheuristics\",\"Combinatorial optimization\",\"Operation research\",\"Planification\",\"Images satellite\",\"Metaheuristiques\",\"Optimisation multi-objectif\",\"Optimisation combinatoire\",\"Recherche opérationnelle\",\"[INFO.INFO-RO] Computer Science/Operations Research\"],\"creators\":[\"Tangpattanakul, Panwadee\"],\"publicationdate\":\"2013-09-26\",\"publisher\":\"HAL CCSD\",\"embargoenddate\":\"\",\"contributor\":[\"LAAS-MOGISA ; Laboratoire d\\u0027analyse et d\\u0027architecture des systèmes [Toulouse] (LAAS) ; CNRS - Université Paul Sabatier (UPS) - Toulouse III - Institut National Polytechnique de Toulouse - INPT - Institut National des Sciences Appliquées [INSA] - Toulouse - CNRS - Université Paul Sabatier (UPS) - Toulouse III - Institut National Polytechnique de Toulouse - INPT - Institut National des Sciences Appliquées [INSA] - Toulouse\",\"INSA de Toulouse\",\"P.LOPEZ\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[],\"instances\":[{\"url\":\"https://tel.archives-ouvertes.fr/tel-00903756\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://tel.archives-ouvertes.fr/tel-00903756\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Doctoral thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://tel.archives-ouvertes.fr/tel-00903756\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Doctoral thesis\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://tel.archives-ouvertes.fr/tel-00903756\",\"id\":\"oai:tel.archives-ouvertes.fr:tel-00903756\"},\"trust\":0.8168962}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:tel-00903756v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Tangpattanakul, Panwadee"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:tel.archives-ouvertes.fr:tel-00903756"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Satellite Images","Planning","Multi-objective optimization","Metaheuristics","Combinatorial optimization","Operation research","Planification","Images satellite","Metaheuristiques","Optimisation multi-objectif","Optimisation combinatoire","Recherche opérationnelle","[INFO.INFO-RO] Computer Science/Operations Research"]},"trust":{"type":"FLOAT","value":0.8168962},"target_publication_title":{"type":"STRING","value":"Optimisation multi-objectif de missions de satellites d\u0027observation de la Terre"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"2013-09-26"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:519014\",\"titles\":[\"Stochastic modeling of empirical time series of childhood infectious diseases data before and after mass vaccination\"],\"abstracts\":[\"The goal of this paper is to analyze the stochastic dynamics of childhood infectious disease time series. We present an univariate time series analysis of pertussis, mumps, measles and rubella based on Box-Jenkins or AutoRegressive Integrated Moving Average (ARIMA) modeling. The method, which enables the dependency structure embedded in time series data to be modeled, has potential research applications in studies of infectious disease dynamics. Canadian chronological series of pertussis, mumps, measles and rubella, before and after mass vaccination, are analyzed to characterize the statistical structure of these diseases. Despite the fact that these infectious diseases are biologically different, it is found that they are all represented by simple models with the same basic statistical structure. Aside from seasonal effects, the number of new cases is given by the incidence in the previous period and by periodically recurrent random factors. It is also shown that mass vaccination does not change this stochastic dependency. 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Researchers have examined the challenges of introducing new ways of working--\\u0027organisational innovations\\u0027--into complex organisations such as the NHS, and this has given rise to a much better understanding of how this takes place--and why seemingly good ideas do not always result in changes in practice. However, there has been less research on the medium- and longer-term outcomes for organisational innovations and on the question of how new ways of working, introduced by frontline clinicians and managers, are sustained and become established in day-to-day practice. Clearly, this question of sustainability is crucial if the gains in patient care that derive from organisational innovations are to be maintained, rather than lost to what the NHS Institute has called the \\u0027improvement-evaporation effect\\u0027. Methods The study will involve research in four case-study sites around England, each of which was successful in sustaining its new model of service provision beyond an initial period of pilot funding for new genetics services provided by the Department of Health. Building on findings relating to the introduction and sustainability of these services already gained from an earlier study, the research will use qualitative methods--in-depth interviews, observation of key meetings, and analysis of relevant documents--to understand the longer-term challenges involved in each case and how these were surmounted. The research will provide lessons for those seeking to sustain their own organisational innovations in wide-ranging clinical areas and for those designing the systems and organisations that make up the NHS, to make them more receptive contexts for the sustainment of innovation. Discussion Through comparison and contrast across four sites, each involving different organisational innovations, different forms of leadership, and different organisational contexts to contend with, the findings of the study will have wide relevance. 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Methods The study will involve research in four case-study sites around England, each of which was successful in sustaining its new model of service provision beyond an initial period of pilot funding for new genetics services provided by the Department of Health. Building on findings relating to the introduction and sustainability of these services already gained from an earlier study, the research will use qualitative methods--in-depth interviews, observation of key meetings, and analysis of relevant documents--to understand the longer-term challenges involved in each case and how these were surmounted. The research will provide lessons for those seeking to sustain their own organisational innovations in wide-ranging clinical areas and for those designing the systems and organisations that make up the NHS, to make them more receptive contexts for the sustainment of innovation. Discussion Through comparison and contrast across four sites, each involving different organisational innovations, different forms of leadership, and different organisational contexts to contend with, the findings of the study will have wide relevance. 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There are also examples of plant viruses that rely on chaperone systems in the endoplasmic reticulum (ER) to support cell-to-cell movement. TMV relies on calreticulin to promote virus intercellular transport. Calreticulin also resides in the plasmodesmata and plays a role in calcium sequestration as well as glycoprotein folding. The pomovirus TGB2 interacts with RME-8 in the endosome. The potexvirus TGB3 protein stimulates expression of ER resident chaperones via the bZIP60 transcription factor. Up-regulating factors involved in protein folding may be essential to handling the load of viral proteins translated along the ER. In addition, TGB3 stimulates SKP1 which is a co-factor in proteasomal degradation of cellular proteins. 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We conducted a spatial analysis to determine the geographic variation of liver cancer and its association with the proportion of immigration in Ontario. Liver cancer incidence data between 1998 and 2002 were obtained from the Ontario Cancer Registry. The Canadian Community Health Survey (CCHS) in 2001 provided information on potential risk factors. Results Age standardized incidence ratios (SIR) for liver cancer and prevalence of potential risk factors were calculated for each of 35 health regions. The SIRs for liver cancer varied across the 35 health regions (p \\u003c 0.01). Toronto and York health regions had a significantly higher SIR than other regions, indicated by the Scan method (p \\u003c 0.001). Poisson models with and without random effects were fitted to determine independent ecological contributors. After adjustment for sex, age and spatial location, the proportion of immigrants remained a significant determinant. Smoking, alcohol drinking, physical activity, education, income, obesity and diabetes did not substantially explain the geographic variation of liver cancer in Ontario. Conclusion Immigration is an important reason for the clustering of liver cancer in Ontario. More attention should be paid to areas with a high proportion of immigrants.\"],\"language\":\"eng\",\"subjects\":[\"Research\"],\"creators\":[\"Chen, Yue\",\"Yi, Qilong\",\"Mao, Yang\"],\"publicationdate\":\"2008-06-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"International Journal of Health Geographics\",\"issn\":\"\",\"eissn\":\"1476-072X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1476-072X-7-28\",\"type\":\"doi\"},{\"value\":\"PMC2426679\",\"type\":\"pmc\"},{\"value\":\"18518988\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC2426679\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.ij-healthgeographics.com/content/7/1/28\",\"license\":\"OPEN\",\"hostedby\":\"International Journal of Health Geographics\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.ij-healthgeographics.com/content/7/1/28\",\"license\":\"OPEN\",\"hostedby\":\"International Journal of Health Geographics\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.ij-healthgeographics.com/content/7/1/28\",\"id\":\"oai:doaj.org/article:cd98cd170c9d4a4c95961cc601438a78\"},\"trust\":0.95062727}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:1072733"},"target_publication_author_list":{"type":"LIST_STRING","value":["Chen, Yue","Yi, Qilong","Mao, Yang"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:cd98cd170c9d4a4c95961cc601438a78"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research"]},"trust":{"type":"FLOAT","value":0.95062727},"target_publication_title":{"type":"STRING","value":"Cluster of liver cancer and immigration: A geographic analysis of incidence data for Ontario 1998–2002"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2008-06-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3570317\",\"titles\":[\"Tuberculosis of the Penis: A Review of the Literature\"],\"abstracts\":[\"Background. Tuberculosis of the penis (TBP) is rare. Aim. To review the literature. Method. Various internet data bases were searched. Literature Review. TBP could be primary or secondary, may develop following circumcision performed by a person who had pulmonary Tb, and may be transmitted to the penis from ejaculation, contamination from clothing, or from contact with endometrial secretions, following an earlier pulmonary Tb or Tb elsewhere. TBP presents with a painless/painful small nodule, ulcer, mass on penis which gradually enlarges, and induration/swelling of penis, with or without erectile dysfunction. Inguinal lymph nodes may or may not be palpable. The patient\\u0027s voiding is normal. There may or may not be history of circumcision, pulmonary Tb, and BCG immunization. TBP mimics penile carcinoma, granulomatous syphilis penile ulcer, genital herpes simplex, granuloma inguinale, and HIV infection. Diagnosis is established by microscopic examination finding of granulomas +/−AFB in penile discharge or biopsy of lesion or culture of Tb organism from discharge or biopsy specimens or positive Elisa serology/PCR for Tb. PTBs respond to first- or 2nd-line anti-Tb 6-month treatment. Close contacts should be screened. Extrapulmonary Tb should be excluded. Conclusions. Clinicians should consider possibility of PTB in cases of penile lesions and erectile failure.\"],\"language\":\"eng\",\"subjects\":[\"Review Article\"],\"creators\":[\"Venyo, Anthony Kodzo-Grey\"],\"publicationdate\":\"2015-09-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Scientifica\",\"issn\":\"\",\"eissn\":\"2090-908X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2015/601624\",\"type\":\"doi\"},{\"value\":\"PMC4578738\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4578738\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2015/601624\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2015/601624\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2015/601624\",\"id\":\"oai:doaj.org/article:2ef4a45eb024439cb4de67e84014a631\"},\"trust\":0.24780291}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3570317"},"target_publication_author_list":{"type":"LIST_STRING","value":["Venyo, Anthony Kodzo-Grey"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:2ef4a45eb024439cb4de67e84014a631"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Review Article"]},"trust":{"type":"FLOAT","value":0.24780291},"target_publication_title":{"type":"STRING","value":"Tuberculosis of the Penis: A Review of the Literature"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2015-09-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:ner:maastr:urn:nbn:nl:ui:27-5905\",\"titles\":[\"When unit roots matter: excess volatility and excess smoothness of long-term interest rates.\"],\"abstracts\":[],\"language\":\"und\",\"subjects\":[],\"creators\":[\"Schotman, P.\"],\"publicationdate\":\"2001-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Research Papers in Economics\"],\"pids\":[],\"instances\":[{\"url\":\"http://arno.unimaas.nl/show.cgi?fid\\u003d2690\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"},{\"url\":\"http://www.minneapolisfed.org/research/common/pub_detail.cfm?pb_autonum_id\\u003d42\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.minneapolisfed.org/research/common/pub_detail.cfm?pb_autonum_id\\u003d42\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}]},\"provenance\":{\"repositoryName\":\"Research Papers in Economics\",\"url\":\"http://www.minneapolisfed.org/research/common/pub_detail.cfm?pb_autonum_id\\u003d42\",\"id\":\"oai:RePEc:fip:fedmem:44\"},\"trust\":0.9902673}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_publication_id":{"type":"STRING","value":"oai:RePEc:ner:maastr:urn:nbn:nl:ui:27-5905"},"target_publication_author_list":{"type":"LIST_STRING","value":["Schotman, P."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:RePEc:fip:fedmem:44"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"},"trust":{"type":"FLOAT","value":0.9902673},"target_publication_title":{"type":"STRING","value":"When unit roots matter: excess volatility and excess smoothness of long-term interest rates."},"provenance_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_dateofacceptance":{"type":"DATE","value":"2001-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MISSING/ABSTRACT","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:ner:maastr:urn:nbn:nl:ui:27-5905\",\"titles\":[\"When unit roots matter: excess volatility and excess smoothness of long-term interest rates.\"],\"abstracts\":[\"This paper reexamines volatility tests of the expectations model of the term structure of interest rates. 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When used in conjunction with electrical stimulation, they are prone to prolonged, saturating stimulation artifacts that prevent the recording of short-latency evoked responses. Yet electrical stimulation is integral to many experimental designs, and critical for emerging brain-computer interfacing and neuroprosthetic applications. To address these issues, we developed an easy-to-use, modifiable, and inexpensive system for multielectrode neural recording and stimulation. Setup costs are less than US$10,000 for 64 channels, an order of magnitude lower than comparable commercial systems. Unlike commercial equipment, the system recovers rapidly from stimulation and allows short-latency action potentials (\\u003c1 ms post-stimulus) to be detected, facilitating closed-loop applications and exposing neural activity that would otherwise remain hidden. To illustrate this capability, evoked activity from microstimulation of the rodent hippocampus is presented. 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Since maintaining wired headstage connections with freely moving animals is difficult, we describe a new method of electrode-headstage coupling using neodymium magnets.\"],\"language\":\"eng\",\"subjects\":[\"Neuroscience\",\"Original Research\",\"data acquisition system\",\"multi-electrode array\",\"stimulation artifact\",\"local field potential\",\"recording\",\"microstimulation\",\"hippocampus\",\"population spike\"],\"creators\":[\"Rolston, John D.\",\"Gross, Robert E.\",\"Potter, Steve M.\"],\"publicationdate\":\"2009-07-01\",\"publisher\":\"Frontiers Research Foundation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Frontiers in Neuroengineering\",\"issn\":\"\",\"eissn\":\"1662-6443\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3389/neuro.16.012.2009\",\"type\":\"doi\"},{\"value\":\"PMC2722905\",\"type\":\"pmc\"},{\"value\":\"19668698\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC2722905\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.3389/neuro.16.012.2009\",\"license\":\"OPEN\",\"hostedby\":\"Frontiers in Neuroengineering\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.3389/neuro.16.012.2009\",\"license\":\"OPEN\",\"hostedby\":\"Frontiers in Neuroengineering\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Frontiers\",\"url\":\"http://dx.doi.org/10.3389/neuro.16.012.2009\",\"id\":\"10.3389/neuro.16.012.2009\"},\"trust\":0.3759628}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:1869636"},"target_publication_author_list":{"type":"LIST_STRING","value":["Rolston, John D.","Gross, Robert E.","Potter, Steve M."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["10.3389/neuro.16.012.2009"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::3db634fc5446f389d0b826ea400a5da6"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Neuroscience","Original Research","data acquisition system","multi-electrode array","stimulation artifact","local field potential","recording","microstimulation","hippocampus","population spike"]},"trust":{"type":"FLOAT","value":0.3759628},"target_publication_title":{"type":"STRING","value":"A Low-Cost Multielectrode System for Data Acquisition Enabling Real-Time Closed-Loop Processing with Rapid Recovery from Stimulation Artifacts"},"provenance_datasource_name":{"type":"STRING","value":"Frontiers"},"target_dateofacceptance":{"type":"DATE","value":"2009-07-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:118602\",\"titles\":[\"Recovery and phylogenetic analysis of novel archaeal rRNA sequences from a deep-sea deposit feeder.\"],\"abstracts\":[\"In 1992, two independent reports based on small-subunit rRNA gene (SSU rDNA) cloning revealed the presence of novel Archaea among marine bacterioplankton. Here, we report the presence of further novel Archaea SSU rDNA sequences recovered from the midgut contents of a deep-sea marine holothurian. Phylogenetic analyses show that these abyssal Archaea are a paraphyletic component of a highly divergent clade that also includes some planktonic sequences. Our data confirm that this clade is a deep-branching lineage in the tree of life.\"],\"language\":\"eng\",\"subjects\":[\"Research Article\"],\"creators\":[\"Mcinerney, J. O.\",\"Wilkinson, M.\",\"Patching, J. W.\",\"Embley, T. 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Here, we report the presence of further novel Archaea SSU rDNA sequences recovered from the midgut contents of a deep-sea marine holothurian. Phylogenetic analyses show that these abyssal Archaea are a paraphyletic component of a highly divergent clade that also includes some planktonic sequences. Our data confirm that this clade is a deep-branching lineage in the\\r\\ntree of life.\"],\"language\":\"und\",\"subjects\":[\"Biology\"],\"creators\":[\"Mcinerney, James O.\",\"Wilkinson, Mark\",\"Patching, John W.\",\"Embley, T. 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Here, we report the presence of further novel Archaea SSU rDNA sequences recovered from the midgut contents of a deep-sea marine holothurian. Phylogenetic analyses show that these abyssal Archaea are a paraphyletic component of a highly divergent clade that also includes some planktonic sequences. Our data confirm that this clade is a deep-branching lineage in the\\r\\ntree of life.\"],\"language\":\"und\",\"subjects\":[\"Biology\"],\"creators\":[\"Mcinerney, James O.\",\"Wilkinson, Mark\",\"Patching, John W.\",\"Embley, T. 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Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). Methods In Dawei, southern Myanmar, three pLDH based RDTs (CareStart™ Malaria pLDH (Pan), CareStart™ Malaria pLDH (Pan, Pf) and OptiMAL-IT®)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. Results Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria™ pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4] OptiMal-IT® : Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7] CareStart Malaria™ pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI9585.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI9571.1-84.4], spec 97.8% [CI95 96.3-98.7] Inter-observer agreement was excellent for all tests (kappa \\u003e 0.9). The median time for the RDTs to become negative was two days for the CareStart™ Malaria tests and seven days for OptiMAL-IT®. Tests were heat stable up to 90 days except for OptiMAL-IT® (Pf specific pLDH stable to day 20 at 35°C). Conclusion None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT® performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified.\"],\"language\":\"eng\",\"subjects\":[\"Research\"],\"creators\":[\"Ashley, Elizabeth A.\",\"Touabi, Malek\",\"Ahrer, Margareta\",\"Hutagalung, Robert\",\"Htun, Khayae\",\"Luchavez, Jennifer\",\"Dureza, Christine\",\"Proux, Stephane\",\"Leimanis, Mara\",\"Lwin, Myo Min\"],\"publicationdate\":\"2009-10-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Malaria Journal\",\"issn\":\"\",\"eissn\":\"1475-2875\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1475-2875-8-241\",\"type\":\"doi\"},{\"value\":\"PMC2774865\",\"type\":\"pmc\"},{\"value\":\"19860920\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC2774865\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"license\":\"OPEN\",\"hostedby\":\"Malaria Journal\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"license\":\"OPEN\",\"hostedby\":\"Malaria Journal\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"id\":\"oai:doaj.org/article:d52e1a9e9ecd4f14a30519b3856b6041\"},\"trust\":0.34640795}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:1890104"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ashley, Elizabeth A.","Touabi, Malek","Ahrer, Margareta","Hutagalung, Robert","Htun, Khayae","Luchavez, Jennifer","Dureza, Christine","Proux, Stephane","Leimanis, Mara","Lwin, Myo Min"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:d52e1a9e9ecd4f14a30519b3856b6041"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research"]},"trust":{"type":"FLOAT","value":0.34640795},"target_publication_title":{"type":"STRING","value":"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2009-10-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/PID","payload":"{\"publication\":{\"originalId\":\"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"titles\":[\"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria.\"],\"abstracts\":[\"BACKGROUND: In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). METHODS: In Dawei, southern Myanmar, three pLDH based RDTs (CareStart Malaria pLDH (Pan), CareStart Malaria pLDH (Pan, Pf) and OptiMAL-IT)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. RESULTS: Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4]. OptiMal-IT: Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7]. CareStart Malaria pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI95 85.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI95 71.1-84.4], spec 97.8% [CI95 96.3-98.7]. Inter-observer agreement was excellent for all tests (kappa \\u003e 0.9). The median time for the RDTs to become negative was two days for the CareStart Malaria tests and seven days for OptiMAL-IT. Tests were heat stable up to 90 days except for OptiMAL-IT (Pf specific pLDH stable to day 20 at 35 degrees C). CONCLUSION: None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified.\"],\"language\":\"eng\",\"subjects\":[\"Animals\",\"Humans\",\"Plasmodium falciparum\",\"Plasmodium vivax\",\"Malaria, Falciparum\",\"Malaria, Vivax\",\"L-Lactate Dehydrogenase\",\"Reagent Kits, Diagnostic\",\"Microscopy\",\"Diagnostic Tests, Routine\",\"Sensitivity and Specificity\",\"Prospective Studies\",\"Predictive Value of Tests\",\"Polymerase Chain Reaction\",\"Blood Specimen Collection\",\"Adolescent\",\"Adult\",\"Aged\",\"Aged, 80 and over\",\"Child\",\"Child, Preschool\",\"Infant, Newborn\",\"Infant\",\"Middle Aged\",\"Myanmar\",\"Young Adult\",\"Female\",\"Male\"],\"creators\":[\"Ashley, Ea\",\"Touabi, M.\",\"Ahrer, M.\",\"Hutagalung, R.\",\"Htun, K.\",\"Luchavez, J.\",\"Dureza, C.\",\"Proux, S.\",\"Leimanis, M.\",\"Lwin, Mm\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Oxford University Research Archive\"],\"pids\":[{\"value\":\"10.1186/1475-2875-8-241\",\"type\":\"doi\"},{\"value\":\"PMC2774865\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://ora.ox.ac.uk/objects/uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"license\":\"RESTRICTED\",\"hostedby\":\"Oxford University Research Archive\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"pids\":[{\"value\":\"PMC2774865\",\"type\":\"pmc\"}]},\"provenance\":{\"repositoryName\":\"Europe PubMed Central\",\"url\":\"http://europepmc.org/articles/PMC2774865\",\"id\":\"oai:europepmc.org:1890104\"},\"trust\":0.9894282}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Oxford University Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ashley, Ea","Touabi, M.","Ahrer, M.","Hutagalung, R.","Htun, K.","Luchavez, J.","Dureza, C.","Proux, S.","Leimanis, M.","Lwin, Mm"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:europepmc.org:1890104"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Animals","Humans","Plasmodium falciparum","Plasmodium vivax","Malaria, Falciparum","Malaria, Vivax","L-Lactate Dehydrogenase","Reagent Kits, Diagnostic","Microscopy","Diagnostic Tests, Routine","Sensitivity and Specificity","Prospective Studies","Predictive Value of Tests","Polymerase Chain Reaction","Blood Specimen Collection","Adolescent","Adult","Aged","Aged, 80 and over","Child","Child, Preschool","Infant, Newborn","Infant","Middle Aged","Myanmar","Young Adult","Female","Male"]},"trust":{"type":"FLOAT","value":0.9894282},"target_publication_title":{"type":"STRING","value":"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria."},"provenance_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::2290a7385ed77cc5592dc2153229f082"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/PID","payload":"{\"publication\":{\"originalId\":\"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"titles\":[\"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria.\"],\"abstracts\":[\"BACKGROUND: In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). METHODS: In Dawei, southern Myanmar, three pLDH based RDTs (CareStart Malaria pLDH (Pan), CareStart Malaria pLDH (Pan, Pf) and OptiMAL-IT)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. RESULTS: Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4]. OptiMal-IT: Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7]. CareStart Malaria pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI95 85.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI95 71.1-84.4], spec 97.8% [CI95 96.3-98.7]. Inter-observer agreement was excellent for all tests (kappa \\u003e 0.9). The median time for the RDTs to become negative was two days for the CareStart Malaria tests and seven days for OptiMAL-IT. Tests were heat stable up to 90 days except for OptiMAL-IT (Pf specific pLDH stable to day 20 at 35 degrees C). CONCLUSION: None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified.\"],\"language\":\"eng\",\"subjects\":[\"Animals\",\"Humans\",\"Plasmodium falciparum\",\"Plasmodium vivax\",\"Malaria, Falciparum\",\"Malaria, Vivax\",\"L-Lactate Dehydrogenase\",\"Reagent Kits, Diagnostic\",\"Microscopy\",\"Diagnostic Tests, Routine\",\"Sensitivity and Specificity\",\"Prospective Studies\",\"Predictive Value of Tests\",\"Polymerase Chain Reaction\",\"Blood Specimen Collection\",\"Adolescent\",\"Adult\",\"Aged\",\"Aged, 80 and over\",\"Child\",\"Child, Preschool\",\"Infant, Newborn\",\"Infant\",\"Middle Aged\",\"Myanmar\",\"Young Adult\",\"Female\",\"Male\"],\"creators\":[\"Ashley, Ea\",\"Touabi, M.\",\"Ahrer, M.\",\"Hutagalung, R.\",\"Htun, K.\",\"Luchavez, J.\",\"Dureza, C.\",\"Proux, S.\",\"Leimanis, M.\",\"Lwin, Mm\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Oxford University Research Archive\"],\"pids\":[{\"value\":\"10.1186/1475-2875-8-241\",\"type\":\"doi\"},{\"value\":\"19860920\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://ora.ox.ac.uk/objects/uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"license\":\"RESTRICTED\",\"hostedby\":\"Oxford University Research Archive\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"pids\":[{\"value\":\"19860920\",\"type\":\"pmid\"}]},\"provenance\":{\"repositoryName\":\"Europe PubMed Central\",\"url\":\"http://europepmc.org/articles/PMC2774865\",\"id\":\"oai:europepmc.org:1890104\"},\"trust\":0.9894282}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Oxford University Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ashley, Ea","Touabi, M.","Ahrer, M.","Hutagalung, R.","Htun, K.","Luchavez, J.","Dureza, C.","Proux, S.","Leimanis, M.","Lwin, Mm"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:europepmc.org:1890104"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Animals","Humans","Plasmodium falciparum","Plasmodium vivax","Malaria, Falciparum","Malaria, Vivax","L-Lactate Dehydrogenase","Reagent Kits, Diagnostic","Microscopy","Diagnostic Tests, Routine","Sensitivity and Specificity","Prospective Studies","Predictive Value of Tests","Polymerase Chain Reaction","Blood Specimen Collection","Adolescent","Adult","Aged","Aged, 80 and over","Child","Child, Preschool","Infant, Newborn","Infant","Middle Aged","Myanmar","Young Adult","Female","Male"]},"trust":{"type":"FLOAT","value":0.9894282},"target_publication_title":{"type":"STRING","value":"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria."},"provenance_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::2290a7385ed77cc5592dc2153229f082"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"titles\":[\"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria.\"],\"abstracts\":[\"BACKGROUND: In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). METHODS: In Dawei, southern Myanmar, three pLDH based RDTs (CareStart Malaria pLDH (Pan), CareStart Malaria pLDH (Pan, Pf) and OptiMAL-IT)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. RESULTS: Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4]. OptiMal-IT: Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7]. CareStart Malaria pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI95 85.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI95 71.1-84.4], spec 97.8% [CI95 96.3-98.7]. Inter-observer agreement was excellent for all tests (kappa \\u003e 0.9). The median time for the RDTs to become negative was two days for the CareStart Malaria tests and seven days for OptiMAL-IT. Tests were heat stable up to 90 days except for OptiMAL-IT (Pf specific pLDH stable to day 20 at 35 degrees C). CONCLUSION: None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified.\"],\"language\":\"eng\",\"subjects\":[\"Animals\",\"Humans\",\"Plasmodium falciparum\",\"Plasmodium vivax\",\"Malaria, Falciparum\",\"Malaria, Vivax\",\"L-Lactate Dehydrogenase\",\"Reagent Kits, Diagnostic\",\"Microscopy\",\"Diagnostic Tests, Routine\",\"Sensitivity and Specificity\",\"Prospective Studies\",\"Predictive Value of Tests\",\"Polymerase Chain Reaction\",\"Blood Specimen Collection\",\"Adolescent\",\"Adult\",\"Aged\",\"Aged, 80 and over\",\"Child\",\"Child, Preschool\",\"Infant, Newborn\",\"Infant\",\"Middle Aged\",\"Myanmar\",\"Young Adult\",\"Female\",\"Male\"],\"creators\":[\"Ashley, Ea\",\"Touabi, M.\",\"Ahrer, M.\",\"Hutagalung, R.\",\"Htun, K.\",\"Luchavez, J.\",\"Dureza, C.\",\"Proux, S.\",\"Leimanis, M.\",\"Lwin, Mm\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Oxford University Research Archive\"],\"pids\":[{\"value\":\"10.1186/1475-2875-8-241\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://ora.ox.ac.uk/objects/uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"license\":\"RESTRICTED\",\"hostedby\":\"Oxford University Research Archive\",\"instancetype\":\"Unknown\"},{\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"license\":\"OPEN\",\"hostedby\":\"Malaria Journal\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"license\":\"OPEN\",\"hostedby\":\"Malaria Journal\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"id\":\"oai:doaj.org/article:d52e1a9e9ecd4f14a30519b3856b6041\"},\"trust\":0.8181293}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Oxford University Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ashley, Ea","Touabi, M.","Ahrer, M.","Hutagalung, R.","Htun, K.","Luchavez, J.","Dureza, C.","Proux, S.","Leimanis, M.","Lwin, Mm"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:d52e1a9e9ecd4f14a30519b3856b6041"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Animals","Humans","Plasmodium falciparum","Plasmodium vivax","Malaria, Falciparum","Malaria, Vivax","L-Lactate Dehydrogenase","Reagent Kits, Diagnostic","Microscopy","Diagnostic Tests, Routine","Sensitivity and Specificity","Prospective Studies","Predictive Value of Tests","Polymerase Chain Reaction","Blood Specimen Collection","Adolescent","Adult","Aged","Aged, 80 and over","Child","Child, Preschool","Infant, Newborn","Infant","Middle Aged","Myanmar","Young Adult","Female","Male"]},"trust":{"type":"FLOAT","value":0.8181293},"target_publication_title":{"type":"STRING","value":"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria."},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::2290a7385ed77cc5592dc2153229f082"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MISSING/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"titles\":[\"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria.\"],\"abstracts\":[\"BACKGROUND: In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). METHODS: In Dawei, southern Myanmar, three pLDH based RDTs (CareStart Malaria pLDH (Pan), CareStart Malaria pLDH (Pan, Pf) and OptiMAL-IT)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. RESULTS: Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4]. OptiMal-IT: Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7]. CareStart Malaria pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI95 85.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI95 71.1-84.4], spec 97.8% [CI95 96.3-98.7]. Inter-observer agreement was excellent for all tests (kappa \\u003e 0.9). The median time for the RDTs to become negative was two days for the CareStart Malaria tests and seven days for OptiMAL-IT. Tests were heat stable up to 90 days except for OptiMAL-IT (Pf specific pLDH stable to day 20 at 35 degrees C). CONCLUSION: None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified.\"],\"language\":\"eng\",\"subjects\":[\"Animals\",\"Humans\",\"Plasmodium falciparum\",\"Plasmodium vivax\",\"Malaria, Falciparum\",\"Malaria, Vivax\",\"L-Lactate Dehydrogenase\",\"Reagent Kits, Diagnostic\",\"Microscopy\",\"Diagnostic Tests, Routine\",\"Sensitivity and Specificity\",\"Prospective Studies\",\"Predictive Value of Tests\",\"Polymerase Chain Reaction\",\"Blood Specimen Collection\",\"Adolescent\",\"Adult\",\"Aged\",\"Aged, 80 and over\",\"Child\",\"Child, Preschool\",\"Infant, Newborn\",\"Infant\",\"Middle Aged\",\"Myanmar\",\"Young Adult\",\"Female\",\"Male\"],\"creators\":[\"Ashley, Ea\",\"Touabi, M.\",\"Ahrer, M.\",\"Hutagalung, R.\",\"Htun, K.\",\"Luchavez, J.\",\"Dureza, C.\",\"Proux, S.\",\"Leimanis, M.\",\"Lwin, Mm\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Oxford University Research Archive\"],\"pids\":[{\"value\":\"10.1186/1475-2875-8-241\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://ora.ox.ac.uk/objects/uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a\",\"license\":\"RESTRICTED\",\"hostedby\":\"Oxford University Research Archive\",\"instancetype\":\"Unknown\"},{\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"license\":\"OPEN\",\"hostedby\":\"Malaria Journal\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"license\":\"OPEN\",\"hostedby\":\"Malaria Journal\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.malariajournal.com/content/8/1/241\",\"id\":\"oai:doaj.org/article:d52e1a9e9ecd4f14a30519b3856b6041\"},\"trust\":0.8181293}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Oxford University Research Archive"},"target_publication_id":{"type":"STRING","value":"oai:ora.ox.ac.uk:uuid:7f781d58-4dbf-4dd5-ad8e-97a5c32c831a"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ashley, Ea","Touabi, M.","Ahrer, M.","Hutagalung, R.","Htun, K.","Luchavez, J.","Dureza, C.","Proux, S.","Leimanis, M.","Lwin, Mm"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:d52e1a9e9ecd4f14a30519b3856b6041"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Animals","Humans","Plasmodium falciparum","Plasmodium vivax","Malaria, Falciparum","Malaria, Vivax","L-Lactate Dehydrogenase","Reagent Kits, Diagnostic","Microscopy","Diagnostic Tests, Routine","Sensitivity and Specificity","Prospective Studies","Predictive Value of Tests","Polymerase Chain Reaction","Blood Specimen Collection","Adolescent","Adult","Aged","Aged, 80 and over","Child","Child, Preschool","Infant, Newborn","Infant","Middle Aged","Myanmar","Young Adult","Female","Male"]},"trust":{"type":"FLOAT","value":0.8181293},"target_publication_title":{"type":"STRING","value":"Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria."},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::2290a7385ed77cc5592dc2153229f082"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2132525\",\"titles\":[\"Ten years of integrated care: backwards and forwards. The case of the province of Québec, Canada\"],\"abstracts\":[\"Introduction Québec’s rapidly growing elderly and chronically ill population represents a major challenge to its healthcare delivery system, attributable in part to the system’s focus on acute care and fragmented delivery. Description of policy practice Over the past few years, reforms have been implemented at the provincial policy level to integrate hospital-based, nursing home, homecare and social services in 95 catchment areas. Recent organizational changes in primary care have also resulted in the implementation of family medicine groups and network clinics. Several localized initiatives were also developed to improve integration of care for older persons or persons with chronic diseases. Conclusion and discussion Québec has a history of integration of health and social services at the structural level. Recent evaluations of the current reform show that the care provided by various institutions in the healthcare system is becoming better integrated. The Québec health care system nevertheless continues to face three important challenges in its management of chronic diseases: implementing the reorganization of primary care, successfully integrating primary and secondary care at the clinical level, and developing effective governance and change management. Efforts should focus on strengthening primary care by implementing nurse practitioners, developing a shared information system, and achieving better collaboration between primary and secondary care.\"],\"language\":\"eng\",\"subjects\":[\"Policy\",\"integrated care\",\"health care system\",\"chronic disease\",\"health policy\",\"Quebec/Canada\"],\"creators\":[\"Vedel, Isabelle\",\"Monette, Michele\",\"Beland, François\",\"Monette, Johanne\",\"Bergman, Howard\"],\"publicationdate\":\"2011-03-01\",\"publisher\":\"Igitur publishing\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"International Journal of Integrated Care\",\"issn\":\"\",\"eissn\":\"1568-4156\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"PMC3111887\",\"type\":\"pmc\"},{\"value\":\"21677842\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3111887\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.ijic.org/index.php/ijic/article/view/574\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.ijic.org/index.php/ijic/article/view/574\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.ijic.org/index.php/ijic/article/view/574\",\"id\":\"oai:doaj.org/article:87182c8e860f4645af40eb2e7d8a2528\"},\"trust\":0.41021436}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2132525"},"target_publication_author_list":{"type":"LIST_STRING","value":["Vedel, Isabelle","Monette, Michele","Beland, François","Monette, Johanne","Bergman, Howard"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:87182c8e860f4645af40eb2e7d8a2528"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Policy","integrated care","health care system","chronic disease","health policy","Quebec/Canada"]},"trust":{"type":"FLOAT","value":0.41021436},"target_publication_title":{"type":"STRING","value":"Ten years of integrated care: backwards and forwards. The case of the province of Québec, Canada"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2011-03-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:ihs:ihsesp:238\",\"titles\":[\"Do \\\"Clean Hands\\\" Ensure Healthy Growth? Theory and Practice in the Battle Against Corruption\"],\"abstracts\":[\"This paper analyzes the existing relationship between economic growth and the monitoring of corruption and examines the possible outcome of the implementation of a State reform in order to weed out corruption. Growth is always higher when monitoring is high and therefore corruption eradicated. But growth declines when monitoring against corruption is not too high, say intermediate, so much that it makes an equilibrium with corruption and little monitoring a more growth-enhancing solution. It is also stressed that when reforms to combat corruption appear to be implausible, they tend to curb most productive investments. The model is estimated using a dynamic panel data approach for Italy. Italy has been plagued by corruption and in the late 80s and early 90s several scandals erupted which led to the well-known \\\"Clean Hands\\\" (Mani pulite) inquiries. Empirical results support the theoretical model.\"],\"language\":\"und\",\"subjects\":[\"Corruption, growth, reform, panel data\"],\"creators\":[\"Coppier, Raffaella\",\"Costantini, Mauro\",\"Piga, Gustavo\"],\"publicationdate\":\"2009-05-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Research Papers in Economics\"],\"pids\":[],\"instances\":[{\"url\":\"http://www.ihs.ac.at/publications/eco/es-238.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"},{\"url\":\"http://hdl.handle.net/10419/72678\",\"license\":\"OPEN\",\"hostedby\":\"EconStor\",\"instancetype\":\"Research\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10419/72678\",\"license\":\"OPEN\",\"hostedby\":\"EconStor\",\"instancetype\":\"Research\"}]},\"provenance\":{\"repositoryName\":\"EconStor\",\"url\":\"http://hdl.handle.net/10419/72678\",\"id\":\"oai:econstor.eu:10419/72678\"},\"trust\":0.13242775}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_publication_id":{"type":"STRING","value":"oai:RePEc:ihs:ihsesp:238"},"target_publication_author_list":{"type":"LIST_STRING","value":["Coppier, Raffaella","Costantini, Mauro","Piga, Gustavo"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:econstor.eu:10419/72678"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::7fea637fd6d02b8f0adf6f7dc36aed93"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Corruption, growth, reform, panel data"]},"trust":{"type":"FLOAT","value":0.13242775},"target_publication_title":{"type":"STRING","value":"Do \"Clean Hands\" Ensure Healthy Growth? Theory and Practice in the Battle Against Corruption"},"provenance_datasource_name":{"type":"STRING","value":"EconStor"},"target_dateofacceptance":{"type":"DATE","value":"2009-05-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:econstor.eu:10419/72678\",\"titles\":[\"Do Clean Hands ensure healthy growth? Theory and practice in the battle against corruption\"],\"abstracts\":[\"This paper analyzes the existing relationship between economic growth and the monitoring of corruption and examines the possible outcome of the implementation of a State reform in order to weed out corruption. Growth is always higher when monitoring is high and therefore corruption eradicated. But growth declines when monitoring against corruption is not too high, say intermediate, so much that it makes an equilibrium with corruption and little monitoring a more growth-enhancing solution. It is also stressed that when reforms to combat corruption appear to be implausible, they tend to curb most productive investments. The model is estimated using a dynamic panel data approach for Italy. Italy has been plagued by corruption and in the late 80s and early 90s several scandals erupted which led to the well-known Clean Hands (Mani pulite) inquiries. Empirical results support the theoretical model.\"],\"language\":\"eng\",\"subjects\":[\"C33\",\"D73\",\"K42\",\"ddc:330\",\"corruption\",\"growth\",\"reform\",\"panel data\",\"Wirtschaftswachstum\",\"Korruption\",\"Kriminalpolitik\",\"Makroökonomischer Einfluss\",\"Italien\"],\"creators\":[\"Coppier, Raffaella\",\"Costantini, Mauro\",\"Piga, Gustavo\"],\"publicationdate\":\"2009-01-01\",\"publisher\":\"IHS Wien\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"EconStor\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10419/72678\",\"license\":\"OPEN\",\"hostedby\":\"EconStor\",\"instancetype\":\"Research\"},{\"url\":\"http://www.ihs.ac.at/publications/eco/es-238.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.ihs.ac.at/publications/eco/es-238.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"}]},\"provenance\":{\"repositoryName\":\"Research Papers in Economics\",\"url\":\"http://www.ihs.ac.at/publications/eco/es-238.pdf\",\"id\":\"oai:RePEc:ihs:ihsesp:238\"},\"trust\":0.22395444}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"EconStor"},"target_publication_id":{"type":"STRING","value":"oai:econstor.eu:10419/72678"},"target_publication_author_list":{"type":"LIST_STRING","value":["Coppier, Raffaella","Costantini, Mauro","Piga, Gustavo"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:RePEc:ihs:ihsesp:238"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"},"target_publication_subject_list":{"type":"LIST_STRING","value":["C33","D73","K42","ddc:330","corruption","growth","reform","panel data","Wirtschaftswachstum","Korruption","Kriminalpolitik","Makroökonomischer Einfluss","Italien"]},"trust":{"type":"FLOAT","value":0.22395444},"target_publication_title":{"type":"STRING","value":"Do Clean Hands ensure healthy growth? Theory and practice in the battle against corruption"},"provenance_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_dateofacceptance":{"type":"DATE","value":"2009-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::7fea637fd6d02b8f0adf6f7dc36aed93"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3093817\",\"titles\":[\"Calculating the Number of Cluster Heads Based on the Rate-Distortion Function in Wireless Sensor Networks\"],\"abstracts\":[\"Due to limited resources in wireless sensor nodes, energy efficiency is considered as one of the primary constraints in the design of the topology of wireless sensor networks (WSNs). Since data that are collected by wireless sensor nodes exhibit the characteristics of temporal association, data fusion has also become a very important means of reducing network traffic as well as eliminating data redundancy as far as data transmission is concerned. Another reason for data fusion is that, in many applications, only some of the data that are collected can meet the requirements of the sink node. In this paper, we propose a method to calculate the number of cluster heads or data aggregators during data fusion based on the rate-distortion function. In our discussion, we will first establish an energy consumption model and then describe a method for calculating the number of cluster heads from the point of view of reducing energy consumption. We will also show through theoretical analysis and experimentation that the network topology design based on the rate-distortion function is indeed more energy-efficient.\"],\"language\":\"eng\",\"subjects\":[\"Research Article\"],\"creators\":[\"Yang, Mingxin\",\"He, Jingsha\",\"Zhang, Yuqiang\"],\"publicationdate\":\"2014-07-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"The Scientific World Journal\",\"issn\":\"2356-6140\",\"eissn\":\"1537-744X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2014/602875\",\"type\":\"doi\"},{\"value\":\"PMC4102074\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4102074\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2014/602875\",\"license\":\"OPEN\",\"hostedby\":\"The Scientific World Journal\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2014/602875\",\"license\":\"OPEN\",\"hostedby\":\"The Scientific World Journal\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2014/602875\",\"id\":\"oai:doaj.org/article:5e62186d7d4c42d28c8de9cca5776596\"},\"trust\":0.06825805}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3093817"},"target_publication_author_list":{"type":"LIST_STRING","value":["Yang, Mingxin","He, Jingsha","Zhang, Yuqiang"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:5e62186d7d4c42d28c8de9cca5776596"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research Article"]},"trust":{"type":"FLOAT","value":0.06825805},"target_publication_title":{"type":"STRING","value":"Calculating the Number of Cluster Heads Based on the Rate-Distortion Function in Wireless Sensor Networks"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2014-07-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3287354\",\"titles\":[\"Immunomodulatory Effects of the Agaricus blazei Murrill-Based Mushroom Extract AndoSan in Patients with Multiple Myeloma Undergoing High Dose Chemotherapy and Autologous Stem Cell Transplantation: A Randomized, Double Blinded Clinical Study\"],\"abstracts\":[\"Forty patients with multiple myeloma scheduled to undergo high dose chemotherapy with autologous stem cell support were randomized in a double blinded fashion to receive adjuvant treatment with the mushroom extract AndoSan, containing 82% of Agaricus blazei Murrill (19 patients) or placebo (21 patients). Intake of the study product started on the day of stem cell mobilizing chemotherapy and continued until the end of aplasia after high dose chemotherapy, a period of about seven weeks. Thirty-three patients were evaluable for all study endpoints, while all 40 included patients were evaluable for survival endpoints. In the leukapheresis product harvested after stem cell mobilisation, increased percentages of Treg cells and plasmacytoid dendritic cells were found in patients receiving AndoSan. Also, in this group, a significant increase of serum levels of IL-1ra, IL-5, and IL-7 at the end of treatment was found. Whole genome microarray showed increased expression of immunoglobulin genes, Killer Immunoglobulin Receptor (KIR) genes, and HLA genes in the Agaricus group. Furthermore, AndoSan displayed a concentration dependent antiproliferative effect on mouse myeloma cells in vitro. There were no statistically significant differences in treatment response, overall survival, and time to new treatment. The study was registered with Clinicaltrials.gov NCT00970021.\"],\"language\":\"eng\",\"subjects\":[\"Clinical Study\"],\"creators\":[\"Tangen, Jon-Magnus\",\"Tierens, Anne\",\"Caers, Jo\",\"Binsfeld, Marilene\",\"Olstad, Ole Kristoffer\",\"Trøseid, Anne-Marie Siebke\",\"Wang, Junbai\",\"Tjønnfjord, Geir Erland\",\"Hetland, Geir\"],\"publicationdate\":\"2015-01-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"BioMed Research International\",\"issn\":\"2314-6133\",\"eissn\":\"2314-6141\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2015/718539\",\"type\":\"doi\"},{\"value\":\"PMC4312620\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4312620\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2015/718539\",\"license\":\"OPEN\",\"hostedby\":\"BioMed Research International\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2015/718539\",\"license\":\"OPEN\",\"hostedby\":\"BioMed Research International\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2015/718539\",\"id\":\"oai:doaj.org/article:df329b8b2d5a4f17a09cc01afa11b7ce\"},\"trust\":0.3875966}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3287354"},"target_publication_author_list":{"type":"LIST_STRING","value":["Tangen, Jon-Magnus","Tierens, Anne","Caers, Jo","Binsfeld, Marilene","Olstad, Ole Kristoffer","Trøseid, Anne-Marie Siebke","Wang, Junbai","Tjønnfjord, Geir Erland","Hetland, Geir"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:df329b8b2d5a4f17a09cc01afa11b7ce"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Clinical Study"]},"trust":{"type":"FLOAT","value":0.3875966},"target_publication_title":{"type":"STRING","value":"Immunomodulatory Effects of the Agaricus blazei Murrill-Based Mushroom Extract AndoSan in Patients with Multiple Myeloma Undergoing High Dose Chemotherapy and Autologous Stem Cell Transplantation: A Randomized, Double Blinded Clinical Study"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2015-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2439990\",\"titles\":[\"First report of adult Hyalomma marginatum rufipes (vector of Crimean-Congo haemorrhagic fever virus) on cattle under a continental climate in Hungary\"],\"abstracts\":[\"Background South Hungary is being monitored for the northward spreading of thermophilic ixodid species, therefore ticks were collected from cattle and wild ruminants (red, fallow and roe deer) in the autumn of 2011. Findings Besides indigenous species (1185 Dermacentor reticulatus and 976 Ixodes ricinus), two Hyalomma marginatum rufipes males were found on two cows, in September eight days apart. Conclusions This is the northernmost autochthonous infestation of the type host (cattle) with H. m. rufipes, vector of Crimean-Congo haemorrhagic fever virus. The present findings are suggestive of the moulting success of this Afro-Mediterranean tick species in a continental climate in Central Europe.\"],\"language\":\"eng\",\"subjects\":[\"Short Report\",\"Hyalomma marginatum rufipes\",\"Cattle\",\"Continental climate\",\"Crimean-Congo haemorrhagic fever\"],\"creators\":[\"Hornok, Sándor\",\"Horváth, Gábor\"],\"publicationdate\":\"2012-08-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Parasites \\u0026 Vectors\",\"issn\":\"\",\"eissn\":\"1756-3305\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1756-3305-5-170\",\"type\":\"doi\"},{\"value\":\"PMC3436687\",\"type\":\"pmc\"},{\"value\":\"22889105\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3436687\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1186/1756-3305-5-170\",\"license\":\"OPEN\",\"hostedby\":\"Parasites \\u0026 Vectors\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1186/1756-3305-5-170\",\"license\":\"OPEN\",\"hostedby\":\"Parasites \\u0026 Vectors\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"HEALTH FP7 Publications Database\",\"url\":\"http://dx.doi.org/10.1186/1756-3305-5-170\",\"id\":\"87fa4f8ec01c30a19839125aef046d56\"},\"trust\":0.8571538}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2439990"},"target_publication_author_list":{"type":"LIST_STRING","value":["Hornok, Sándor","Horváth, Gábor"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["87fa4f8ec01c30a19839125aef046d56"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::9d14b9d525a1518d0998707bc962b7c2"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Short Report","Hyalomma marginatum rufipes","Cattle","Continental climate","Crimean-Congo haemorrhagic fever"]},"trust":{"type":"FLOAT","value":0.8571538},"target_publication_title":{"type":"STRING","value":"First report of adult Hyalomma marginatum rufipes (vector of Crimean-Congo haemorrhagic fever virus) on cattle under a continental climate in Hungary"},"provenance_datasource_name":{"type":"STRING","value":"HEALTH FP7 Publications Database"},"target_dateofacceptance":{"type":"DATE","value":"2012-08-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2439990\",\"titles\":[\"First report of adult Hyalomma marginatum rufipes (vector of Crimean-Congo haemorrhagic fever virus) on cattle under a continental climate in Hungary\"],\"abstracts\":[\"Background South Hungary is being monitored for the northward spreading of thermophilic ixodid species, therefore ticks were collected from cattle and wild ruminants (red, fallow and roe deer) in the autumn of 2011. Findings Besides indigenous species (1185 Dermacentor reticulatus and 976 Ixodes ricinus), two Hyalomma marginatum rufipes males were found on two cows, in September eight days apart. Conclusions This is the northernmost autochthonous infestation of the type host (cattle) with H. m. rufipes, vector of Crimean-Congo haemorrhagic fever virus. The present findings are suggestive of the moulting success of this Afro-Mediterranean tick species in a continental climate in Central Europe.\"],\"language\":\"eng\",\"subjects\":[\"Short Report\",\"Hyalomma marginatum rufipes\",\"Cattle\",\"Continental climate\",\"Crimean-Congo haemorrhagic fever\"],\"creators\":[\"Hornok, Sándor\",\"Horváth, Gábor\"],\"publicationdate\":\"2012-08-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Parasites \\u0026 Vectors\",\"issn\":\"\",\"eissn\":\"1756-3305\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1756-3305-5-170\",\"type\":\"doi\"},{\"value\":\"PMC3436687\",\"type\":\"pmc\"},{\"value\":\"22889105\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3436687\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1186/1756-3305-5-170\",\"license\":\"OPEN\",\"hostedby\":\"Unknown Repository\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1186/1756-3305-5-170\",\"license\":\"OPEN\",\"hostedby\":\"Unknown Repository\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Crossref\",\"url\":\"http://dx.doi.org/10.1186/1756-3305-5-170\",\"id\":\"WOS:000308494400001\"},\"trust\":0.43092418}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2439990"},"target_publication_author_list":{"type":"LIST_STRING","value":["Hornok, Sándor","Horváth, Gábor"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["WOS:000308494400001"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::081b82f96300b6a6e3d282bad31cb6e2"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Short Report","Hyalomma marginatum rufipes","Cattle","Continental climate","Crimean-Congo haemorrhagic fever"]},"trust":{"type":"FLOAT","value":0.43092418},"target_publication_title":{"type":"STRING","value":"First report of adult Hyalomma marginatum rufipes (vector of Crimean-Congo haemorrhagic fever virus) on cattle under a continental climate in Hungary"},"provenance_datasource_name":{"type":"STRING","value":"Crossref"},"target_dateofacceptance":{"type":"DATE","value":"2012-08-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:comum.rcaap.pt:123456789/9090\",\"titles\":[\"O poder das rotinas em IP: estudo de caso de uma criança com trissomia 21\"],\"abstracts\":[\"As rotinas na Intervenção Precoce constituem um largo conjunto de experiências do\\nquotidiano que fornecem oportunidades de aprendizagem para a criança, não só para\\nconsolidar as aptidões já adquiridas mas também para adquirir novas.\\nO presente estudo, pretende explorar o papel das rotinas na Intervenção Precoce através de\\num estudo de caso de uma criança com trissomia 21 inserida num grupo de crianças de 5\\nanos que frequenta um jardim-de-infância da rede pública de Lisboa.\\nPara a realização do estudo de caso, utilizaram-se como instrumentos e estratégias de\\nrecolha de dados: a Schedule of Growing Skills II e avaliações nas áreas de competência;\\nfoi realizada uma entrevista à educadora titular do grupo, com o objetivo de conhecer a\\nrotina diária da criança, utilizando a Escala de Avaliação das Impressões dos Educadores\\nacerca das Rotinas e do Envolvimento (EAIERE); elaborou-se o Ecomapa familiar e\\nrealizou-se a Entrevista Baseada nas Rotinas (EBR) em conjunto com a mãe. Procedeu-se\\nde igual forma em conjunto com a mãe, à descrição da sua história clínica,\\ndesenvolvimental e posterior elaboração do Plano Individual de Intervenção Precoce.\\nTodos estes procedimentos assentam na valorização das práticas em Intervenção Precoce\\nnos contextos de vida da criança e sua família, isto é, locais onde ocorrem os seus\\ncomportamentos.\\nAo longo da dissertação será abordada a evolução do conceito de Intervenção no que diz\\nrespeito à sua perspetiva histórico-evolutiva, aspetos legislativos, enquadramento legal e\\npráticas. Nesta dissertação efetuaremos também uma descrição da trissomia 21,\\nnomeadamente dos aspetos da sua evolução em termos conceptuais históricos, bem como\\nreferindo pontos tais como o seu desenvolvimento físico, psicológico e emocional.\\nA dissertação colmatará, com a elaboração de um Plano Individual de Intervenção Precoce,\\nbem como nos seus aspetos processuais.\\nPor fim, na análise crítica sintetizam-se os resultados obtidos na presente dissertação.\",\"The Routines Based Intervention is built upon a vast field of experience from the quotidian\\nthat allow children to have opportunities of gathering knowledge, not only to conserve what\\nthey have already learned but also to learn even more.\\nThe present essay intention is to explore the meaning of the routines in Early Intervation\\nthrough a case study of a Down Syndrome child included in a group of five year old\\nchildren that are attending a public early childhood center in Lisbon.\\nConducting the case study, we used instruments and strategies such as the Schedule of\\nGrowing Skills II and evaluations of different competence areas were used to gather data;\\nan interview was made to the early childhood educator of the group with the goal of\\nlearning about the daily routine of the child by using the “Escala de Avaliação das\\nImpressões dos Educadores acerca das Rotinas e do Envolvimento (EAIERE)”; a family\\nEcomap has been made and an “Entrevista Baseada nas Rotinas (EBR)” took place together\\nwith the child\\u0027s mother. The same method with the mother has been taken to describe the\\nchild\\u0027s developmental history and the elaboration of the individual plan of the early\\nintervention.\\nThe practice of Early Intervention have to take into consideration the child\\u0027s and family life\\nstyle, this is, places where the child\\u0027s behavior take place.\\nThis dissertation will also describe aspects related to Down Syndrome, mainly in its\\nevolution aspects in terms of historical conceptions, as well as the specific characteristics\\nlike it\\u0027s motor, psychological and emotional development.\\nThe dissertation also comprises the development of an individualized early intervention\\nplan, as well as it\\u0027s procedural aspects.\\nAt last, the final considerations summarize some reflections about the process and results\\nobtained in this dissertation.\"],\"language\":\"por\",\"subjects\":[],\"creators\":[\"Sousa, Ana Margarida Ribeiro\"],\"publicationdate\":\"2013-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[\"Serrano, Ana Maria\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Repositório Comum\"],\"pids\":[],\"instances\":[{\"url\":\"http://comum.rcaap.pt/handle/123456789/9090\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Master thesis\"},{\"url\":\"http://hdl.handle.net/10400.26/9090\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Master thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10400.26/9090\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Master thesis\"}]},\"provenance\":{\"repositoryName\":\"Repositório Comum\",\"url\":\"http://hdl.handle.net/10400.26/9090\",\"id\":\"oai:comum.rcaap.pt:10400.26/9090\"},\"trust\":0.5875864}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Repositório Comum"},"target_publication_id":{"type":"STRING","value":"oai:comum.rcaap.pt:123456789/9090"},"target_publication_author_list":{"type":"LIST_STRING","value":["Sousa, Ana Margarida Ribeiro"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:comum.rcaap.pt:10400.26/9090"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::798ed7d4ee7138d49b8828958048130a"},"trust":{"type":"FLOAT","value":0.5875864},"target_publication_title":{"type":"STRING","value":"O poder das rotinas em IP: estudo de caso de uma criança com trissomia 21"},"provenance_datasource_name":{"type":"STRING","value":"Repositório Comum"},"target_dateofacceptance":{"type":"DATE","value":"2013-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::798ed7d4ee7138d49b8828958048130a"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:comum.rcaap.pt:10400.26/9090\",\"titles\":[\"O poder das rotinas em IP: estudo de caso de uma criança com trissomia 21\"],\"abstracts\":[\"As rotinas na Intervenção Precoce constituem um largo conjunto de experiências do\\nquotidiano que fornecem oportunidades de aprendizagem para a criança, não só para\\nconsolidar as aptidões já adquiridas mas também para adquirir novas.\\nO presente estudo, pretende explorar o papel das rotinas na Intervenção Precoce através de\\num estudo de caso de uma criança com trissomia 21 inserida num grupo de crianças de 5\\nanos que frequenta um jardim-de-infância da rede pública de Lisboa.\\nPara a realização do estudo de caso, utilizaram-se como instrumentos e estratégias de\\nrecolha de dados: a Schedule of Growing Skills II e avaliações nas áreas de competência;\\nfoi realizada uma entrevista à educadora titular do grupo, com o objetivo de conhecer a\\nrotina diária da criança, utilizando a Escala de Avaliação das Impressões dos Educadores\\nacerca das Rotinas e do Envolvimento (EAIERE); elaborou-se o Ecomapa familiar e\\nrealizou-se a Entrevista Baseada nas Rotinas (EBR) em conjunto com a mãe. Procedeu-se\\nde igual forma em conjunto com a mãe, à descrição da sua história clínica,\\ndesenvolvimental e posterior elaboração do Plano Individual de Intervenção Precoce.\\nTodos estes procedimentos assentam na valorização das práticas em Intervenção Precoce\\nnos contextos de vida da criança e sua família, isto é, locais onde ocorrem os seus\\ncomportamentos.\\nAo longo da dissertação será abordada a evolução do conceito de Intervenção no que diz\\nrespeito à sua perspetiva histórico-evolutiva, aspetos legislativos, enquadramento legal e\\npráticas. Nesta dissertação efetuaremos também uma descrição da trissomia 21,\\nnomeadamente dos aspetos da sua evolução em termos conceptuais históricos, bem como\\nreferindo pontos tais como o seu desenvolvimento físico, psicológico e emocional.\\nA dissertação colmatará, com a elaboração de um Plano Individual de Intervenção Precoce,\\nbem como nos seus aspetos processuais.\\nPor fim, na análise crítica sintetizam-se os resultados obtidos na presente dissertação.\",\"The Routines Based Intervention is built upon a vast field of experience from the quotidian\\nthat allow children to have opportunities of gathering knowledge, not only to conserve what\\nthey have already learned but also to learn even more.\\nThe present essay intention is to explore the meaning of the routines in Early Intervation\\nthrough a case study of a Down Syndrome child included in a group of five year old\\nchildren that are attending a public early childhood center in Lisbon.\\nConducting the case study, we used instruments and strategies such as the Schedule of\\nGrowing Skills II and evaluations of different competence areas were used to gather data;\\nan interview was made to the early childhood educator of the group with the goal of\\nlearning about the daily routine of the child by using the “Escala de Avaliação das\\nImpressões dos Educadores acerca das Rotinas e do Envolvimento (EAIERE)”; a family\\nEcomap has been made and an “Entrevista Baseada nas Rotinas (EBR)” took place together\\nwith the child\\u0027s mother. The same method with the mother has been taken to describe the\\nchild\\u0027s developmental history and the elaboration of the individual plan of the early\\nintervention.\\nThe practice of Early Intervention have to take into consideration the child\\u0027s and family life\\nstyle, this is, places where the child\\u0027s behavior take place.\\nThis dissertation will also describe aspects related to Down Syndrome, mainly in its\\nevolution aspects in terms of historical conceptions, as well as the specific characteristics\\nlike it\\u0027s motor, psychological and emotional development.\\nThe dissertation also comprises the development of an individualized early intervention\\nplan, as well as it\\u0027s procedural aspects.\\nAt last, the final considerations summarize some reflections about the process and results\\nobtained in this dissertation.\"],\"language\":\"por\",\"subjects\":[],\"creators\":[\"Sousa, Ana Margarida Ribeiro\"],\"publicationdate\":\"2013-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[\"Serrano, Ana Maria\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Repositório Comum\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10400.26/9090\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Master thesis\"},{\"url\":\"http://comum.rcaap.pt/handle/123456789/9090\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Master thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://comum.rcaap.pt/handle/123456789/9090\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Master thesis\"}]},\"provenance\":{\"repositoryName\":\"Repositório Comum\",\"url\":\"http://comum.rcaap.pt/handle/123456789/9090\",\"id\":\"oai:comum.rcaap.pt:123456789/9090\"},\"trust\":0.72646815}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Repositório Comum"},"target_publication_id":{"type":"STRING","value":"oai:comum.rcaap.pt:10400.26/9090"},"target_publication_author_list":{"type":"LIST_STRING","value":["Sousa, Ana Margarida Ribeiro"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:comum.rcaap.pt:123456789/9090"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::798ed7d4ee7138d49b8828958048130a"},"trust":{"type":"FLOAT","value":0.72646815},"target_publication_title":{"type":"STRING","value":"O poder das rotinas em IP: estudo de caso de uma criança com trissomia 21"},"provenance_datasource_name":{"type":"STRING","value":"Repositório Comum"},"target_dateofacceptance":{"type":"DATE","value":"2013-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::798ed7d4ee7138d49b8828958048130a"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:hal.archives-ouvertes.fr:jpa-00254303\",\"titles\":[\"Détermination des contraintes par diffractométrie X dans le cas d\\u0027alliages métalliques polyphasés\"],\"abstracts\":[\"La tenue en service des matériaux métalliques est en grande partie conditionnée par la présence de contraintes résiduelles superficielles. La diffractométrie X est une technique non destructive particulièrement bien adaptée à l\\u0027évaluation de ce type de contraintes. Or, dans le cas d\\u0027alliages métalliques polyphasés, elle ne permet d\\u0027accéder qu\\u0027à l\\u0027état mécanique de la constituante étudiée qui est généralement différent de l\\u0027état mécanique macroscopique du matériau. Les contraintes dans chaque constituant de plusieurs matériaux polyphasés ont été évaluées par diffraction X au cours d\\u0027un essai de traction uniaxiale, les contraintes macroscopiques étant celles appliquées par la machine de traction. Ces contraintes ont aussi été calculées grâce à un modèle micro mécanique. La comparaison des résultats permet de tirer certaines conclusions quant à l\\u0027utilisation de la diffraction X dans le cas des matériaux polyphasés.\"],\"language\":\"fra/fre\",\"subjects\":[\"[PHYS:HIST] Physics/Physics archives\",\"[PHYS:HIST] Physique/Articles anciens\"],\"creators\":[\"Hadmar, P.\",\"Mabelly, P.\",\"Barrallier, L.\",\"Sprauel, J.\"],\"publicationdate\":\"1996-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1051/jp4:1996420\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://hal.archives-ouvertes.fr/jpa-00254303\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"},{\"url\":\"https://hal.archives-ouvertes.fr/jpa-00254303\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/jpa-00254303\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.archives-ouvertes.fr/jpa-00254303\",\"id\":\"oai:HAL:jpa-00254303v1\"},\"trust\":0.18560785}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:hal.archives-ouvertes.fr:jpa-00254303"},"target_publication_author_list":{"type":"LIST_STRING","value":["Hadmar, P.","Mabelly, P.","Barrallier, L.","Sprauel, J."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:jpa-00254303v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[PHYS:HIST] Physics/Physics archives","[PHYS:HIST] Physique/Articles anciens"]},"trust":{"type":"FLOAT","value":0.18560785},"target_publication_title":{"type":"STRING","value":"Détermination des contraintes par diffractométrie X dans le cas d\u0027alliages métalliques polyphasés"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"1996-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:jpa-00254303v1\",\"titles\":[\"Détermination des contraintes par diffractométrie X dans le cas d\\u0027alliages métalliques polyphasés\"],\"abstracts\":[\"La tenue en service des matériaux métalliques est en grande partie conditionnée par la présence de contraintes résiduelles superficielles. La diffractométrie X est une technique non destructive particulièrement bien adaptée à l\\u0027évaluation de ce type de contraintes. Or, dans le cas d\\u0027alliages métalliques polyphasés, elle ne permet d\\u0027accéder qu\\u0027à l\\u0027état mécanique de la constituante étudiée qui est généralement différent de l\\u0027état mécanique macroscopique du matériau. Les contraintes dans chaque constituant de plusieurs matériaux polyphasés ont été évaluées par diffraction X au cours d\\u0027un essai de traction uniaxiale, les contraintes macroscopiques étant celles appliquées par la machine de traction. Ces contraintes ont aussi été calculées grâce à un modèle micro mécanique. La comparaison des résultats permet de tirer certaines conclusions quant à l\\u0027utilisation de la diffraction X dans le cas des matériaux polyphasés.\"],\"language\":\"fra/fre\",\"subjects\":[\"[PHYS.HIST] Physics/Physics archives\"],\"creators\":[\"Hadmar, P.\",\"Mabelly, P.\",\"Barrallier, L.\",\"Sprauel, J.\"],\"publicationdate\":\"1996-01-01\",\"publisher\":\"HAL CCSD\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1051/jp4:1996420\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/jpa-00254303\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"},{\"url\":\"http://hal.archives-ouvertes.fr/jpa-00254303\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hal.archives-ouvertes.fr/jpa-00254303\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"http://hal.archives-ouvertes.fr/jpa-00254303\",\"id\":\"oai:hal.archives-ouvertes.fr:jpa-00254303\"},\"trust\":0.5082343}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:HAL:jpa-00254303v1"},"target_publication_author_list":{"type":"LIST_STRING","value":["Hadmar, P.","Mabelly, P.","Barrallier, L.","Sprauel, J."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:hal.archives-ouvertes.fr:jpa-00254303"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[PHYS.HIST] Physics/Physics archives"]},"trust":{"type":"FLOAT","value":0.5082343},"target_publication_title":{"type":"STRING","value":"Détermination des contraintes par diffractométrie X dans le cas d\u0027alliages métalliques polyphasés"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"1996-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:tel-00520676v1\",\"titles\":[\"Apports combinés de l\\u0027expérimentation et de la modélisation à la compréhension de l\\u0027alcali-réaction et de ses effets mécaniques\"],\"abstracts\":[\"A theoretical approach has been combined with an experimental one in order to better understand the mechanical behaviour of a concrete affected by Alkali-Aggregate Reaction (AAR), and more precisely by Alkali-Silica Reaction. The interest of a model, based on the mechanics of reactive porous media, first appears with the design of the experimental program, which involves more than six hundred samples. A first simple model has affected the choice of the main parameters (external water supply, temperature and stress) and also led us to consider a link between the mechanical consequences and the internal causes of AAR. Experimental data on deformations, cracking, weight variations and mechanical properties have been gathered. Furthermore, various techniques have allowed us to study the evolution of the material microstructure: scanning electron microscopy, visualization of the reaction products by fluorescence of the uranyle ion, mineralogical calculations. The main results are as follows: - The state of stress does not affect the development of the physico-chemical mechanisms involved in AAR. A method, based on \\u0027imposed chemical deformations\\u0027, may thus be proposed for calculting the structures concerned. - Osmotic pressure (or imbibition) appears to play a secondary role on the swelling owing to AAR, which results from the location of the reaction products. - The quantity of water available when the products are formed is a major factor of the swelling amplitude and kinetics. - Swelling can reach 0.1%, using only the water still available after cement hydration. - If the loss of water reaches a critical value, AAR simply stops, waiting for further water supply.- The intrinsic swelling heterogeneity was quantified; it emphasized the interest of a probabilistic framework for modelling AAR. - Monitoring the evolution of the mechanical properties showed that the compressive and splitting tensile strengths are not affected by AAR, whereas the Young\\u0027s modulus decreases by about 30%, because of cracking. - The causes of the free swelling anisotropy are related to the casting direction and concrete anisotropy, regardless of AAR. - The S-shaped deformation curves are due to the increase in the porous space while concrete swells, making diffusion easier and hence accelerating the physicochemical mechanisms. - The swelling acceleration stage greatly determines the deformation kinetics of an AAR-affected concrete. External water supply and, above all, temperature have a major influence on the duration of this stage. All these results have enabled us to identify the parameters of a more advanced model describing the free swelling of a concrete similar to that of many affected structures in Northern France.\",\"Ce travail allie une approche théorique, basée sur la mécanique des milieux poreux réactifs, à une approche expérimentale importante, afin de mieux comprendre le fonctionnement d\\u0027un béton atteint d\\u0027alcali-réaction (plus précisément, de réaction alcali-silice). L\\u0027intérêt de la modélisation se manifeste dès la conception du programme d\\u0027essais, en orientant le choix des principaux paramètres - apports d\\u0027eau, température et contraintes - et en induisant une méthodologie d\\u0027étude qui établit un parallèle entre les effets macroscopiques et les causes microscopiques de l\\u0027alcali-réaction. Le volet expérimental a porté sur les déformations, fissurations, variations de poids et caractéristiques mécaniques de plus de six cents éprouvettes, en gonflement libre ou sous contrainte uniaxiale. Parallèlement, l\\u0027évolution de la microstructure du matériau a été étudiée par différentes techniques: microscope électronique à balayage, visualisation des produits de réaction par fluorescence des ions uranyle, calculs minéralogiques. Les principaux résultats expérimentaux ont été établis sur des bétons ordinaires à base de granulats calcaires (réactifs ou non) et de ciment Portland artificiel. Ils concernent principalement : - l\\u0027absence d\\u0027influence de l\\u0027état de contrainte du matériau sur l\\u0027évolution des processus physico-chimiques constituant l\\u0027alcali-réaction, ce qui permet d\\u0027envisager un calcul d\\u0027ouvrage par une approche de type \\u0027déformations chimiques imposées\\u0027, - le caractère secondaire, sur le plan du gonflement macroscopique, des phénomènes de nature osmotique, et la prépondérance de l\\u0027effet de la localisation des produits de réaction, - le rôle primordial, vis-à-vis du gonflement, de la quantité d\\u0027eau disponible au moment de la formation des produits de réaction, - la possibilité d\\u0027obtention de déformations atteignant 0,1% à partir de la seule eau de gâchage non utilisée par l\\u0027hydratation du ciment, - l\\u0027indépendance des phénomènes de transport d\\u0027eau par rapport à la présence d\\u0027alcaliréaction, - l\\u0027existence d\\u0027un seuil de dessiccation en dessous duquel l\\u0027alcali-réaction est bloquée jusqu\\u0027à l\\u0027arrivée de nouveaux apports d\\u0027eau, - la quantification de l\\u0027hétérogénéité intrinsèque, justifiant l\\u0027introduction d\\u0027un aléa sur le gonflement asymptotique, - le suivi de l\\u0027évolution des caractéristiques mécaniques, montrant le maintien des résistances en compression et en traction par fendage et une chute de l\\u0027ordre de 30% du module d\\u0027Young, liée à la fissuration des éprouvettes, - l\\u0027explication de l\\u0027origine de l\\u0027anisotropie du gonflement libre, due au sens du coulage et à l\\u0027anisotropie du béton, indépendamment de l\\u0027alcali-réaction, - la compréhension des causes de la forme sigmoïdale des courbes de gonflement, résultant de l\\u0027augmentation de l\\u0027espace poreux au fur et à mesure du développement de l\\u0027alcali-réaction et donc de la plus grande facilité de diffusion, - la mise en évidence de l\\u0027importance de la phase d\\u0027accélération des phénomènes (notion de temps de latence), dont la durée dépend des apports d\\u0027eau extérieurs, mais surtout de la température (dont l\\u0027effet est essentiellement cinétique). 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According to species, PRND is located 16–52 kb downstream from the PRNP locus, whereas SPRN is located on another chromosome. The fourth prion-family gene, PRNT, belongs to the same genomic cluster as PRNP and PRND in humans and bovidae. PRNT and PRND possibly resulted from a duplication event of PRND and PRNP, respectively, that occurred early during eutherian species divergence. Although most of the studies concerning the prion-family has been done on PRPc and its involvement in transmissible neurodegenerative disorders, different works report some potential roles of these proteins in the reproductive function of both sexes. Among them, a clear role of PRND, that encodes for the Doppel protein, in male fertility has been demonstrated through gene targeting studies in mice. In other species, Doppel seems to play a role in testis and ovary development but its cellular localization is variable according to the gonadal developmental stage and to the mammalian species considered. For the other three genes, their roles in reproductive function appear ill-defined and/or controversial. The present review aimed to synthesize all the available data on these prion-family members and their relations with reproductive processes, mainly in the gonad of both sexes.\"],\"language\":\"eng\",\"subjects\":[\"Cell and Developmental Biology\",\"Review Article\",\"prion\",\"Doppel\",\"Shadoo\",\"PRT\",\"reproduction\",\"gonads\"],\"creators\":[\"Allais-Bonnet, Aurélie\",\"Pailhoux, Eric\"],\"publicationdate\":\"2014-10-01\",\"publisher\":\"Frontiers Media S.A.\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Frontiers in Cell and Developmental Biology\",\"issn\":\"\",\"eissn\":\"2296-634X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3389/fcell.2014.00056\",\"type\":\"doi\"},{\"value\":\"PMC4207050\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4207050\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.3389/fcell.2014.00056\",\"license\":\"OPEN\",\"hostedby\":\"Frontiers\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.3389/fcell.2014.00056\",\"license\":\"OPEN\",\"hostedby\":\"Frontiers\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Frontiers\",\"url\":\"http://dx.doi.org/10.3389/fcell.2014.00056\",\"id\":\"10.3389/fcell.2014.00056\"},\"trust\":0.2791794}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3185470"},"target_publication_author_list":{"type":"LIST_STRING","value":["Allais-Bonnet, Aurélie","Pailhoux, Eric"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["10.3389/fcell.2014.00056"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::3db634fc5446f389d0b826ea400a5da6"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Cell and Developmental Biology","Review Article","prion","Doppel","Shadoo","PRT","reproduction","gonads"]},"trust":{"type":"FLOAT","value":0.2791794},"target_publication_title":{"type":"STRING","value":"Role of the prion protein family in the gonads"},"provenance_datasource_name":{"type":"STRING","value":"Frontiers"},"target_dateofacceptance":{"type":"DATE","value":"2014-10-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:econstor.eu:10419/91021\",\"titles\":[\"Ouvidoria pública como instrumento de mudança\"],\"abstracts\":[\"The present work points out to show the Public Ombudsman Service as a changing, inclusion and social control tool. As methodology, a bibliography revision was made, besides the author experience in ombudsman service management, showing how the Public Ombudsman Service contributes in building those tasks through the direct and active citizen participation, which represents, a privileged locus to the participative democracy exercise, citizenship achievement and social control of everything that is public. Also, through the ethics valorization, which helps in the civil society renewing, based on the trust and respect rebuilding, which depends on the Public Ombudsman Office`s autonomy and efficiency. 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Como metodologia foi realizada revisão bibliográfica, além de sistematização da experiência do autor na gestão de ouvidoria, demonstrando como a ouvidoria pública contribui na construção destes instrumentos por meio da participação direta e ativa do cidadão. A ouvidoria representa, assim, um lócus privilegiado para o exercício da democracia participativa, conquista da cidadania e controle social da res publica. Por meio da valorização da ética, auxilia na renovação da sociedade civil, a partir da reconstrução da confiança e do respeito, o que depende da autonomia e da eficiência das ouvidorias públicas. Concluiu-se que, para que as ouvidorias públicas concretizem, em plenitude, seu papel de indutor de mudanças, há a necessidade de valorização da ética; adequado perfil e habilidades do ouvidor público; busca da efetividade; e autonomia da ouvidoria pública. The present work points out to show the Public Ombudsman Service as a changing, inclusion and social control tool. 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It may be caused by several congenital and acquired conditions. One such condition is the acromegaloid facial appearance (AFA) syndrome. This condition has been described in approximately eight cases/families. It encompasses a spectrum of acromegaloid physical findings, normal growth hormone (GH) and insulin-like growth factor one (IGF-1) levels, and variable mode of inheritance. The most common physical findings are coarse facies, bulbous nose, and thickened lips. We present a case and a review of the literature on this illness. The patient is a 57-year-old woman who was referred to the endocrinology division for evaluation of suspected acromegaly. She had an acromegaloid appearance since birth as well as a terminal hypertrichosis. Her endocrine laboratory evaluation and chromosomal analyses were normal. AFA needs to be considered when evaluating any patient with pseudoacromegaly. Additional cases/families need to be identified in order to better understand the clinical spectrum, clinical implications, and mode of inheritance of AFA.\"],\"language\":\"eng\",\"subjects\":[\"Case Report\"],\"creators\":[\"Ghazi, Adline\",\"Khosla, Shikha\",\"Becker, Kenneth\"],\"publicationdate\":\"2013-02-01\",\"publisher\":\"Hindawi Publishing Corporation\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Case Reports in Endocrinology\",\"issn\":\"2090-6501\",\"eissn\":\"2090-651X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1155/2013/970396\",\"type\":\"doi\"},{\"value\":\"PMC3600240\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3600240\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.1155/2013/970396\",\"license\":\"OPEN\",\"hostedby\":\"Case Reports in Endocrinology\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.1155/2013/970396\",\"license\":\"OPEN\",\"hostedby\":\"Case Reports in Endocrinology\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://dx.doi.org/10.1155/2013/970396\",\"id\":\"oai:doaj.org/article:71de5e7fdde24bf3a4397672c32379f2\"},\"trust\":0.20350546}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2603670"},"target_publication_author_list":{"type":"LIST_STRING","value":["Ghazi, Adline","Khosla, Shikha","Becker, Kenneth"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:71de5e7fdde24bf3a4397672c32379f2"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Case Report"]},"trust":{"type":"FLOAT","value":0.20350546},"target_publication_title":{"type":"STRING","value":"Acromegaloid Facial Appearance: Case Report and Literature Review"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2013-02-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2132315\",\"titles\":[\"Pathways of Distinction Analysis: A New Technique for Multi–SNP Analysis of GWAS Data\"],\"abstracts\":[\"Genome-wide association studies (GWAS) have become increasingly common due to advances in technology and have permitted the identification of differences in single nucleotide polymorphism (SNP) alleles that are associated with diseases. However, while typical GWAS analysis techniques treat markers individually, complex diseases (cancers, diabetes, and Alzheimers, amongst others) are unlikely to have a single causative gene. Thus, there is a pressing need for multi–SNP analysis methods that can reveal system-level differences in cases and controls. Here, we present a novel multi–SNP GWAS analysis method called Pathways of Distinction Analysis (PoDA). The method uses GWAS data and known pathway–gene and gene–SNP associations to identify pathways that permit, ideally, the distinction of cases from controls. The technique is based upon the hypothesis that, if a pathway is related to disease risk, cases will appear more similar to other cases than to controls (or vice versa) for the SNPs associated with that pathway. By systematically applying the method to all pathways of potential interest, we can identify those for which the hypothesis holds true, i.e., pathways containing SNPs for which the samples exhibit greater within-class similarity than across classes. Importantly, PoDA improves on existing single–SNP and SNP–set enrichment analyses, in that it does not require the SNPs in a pathway to exhibit independent main effects. This permits PoDA to reveal pathways in which epistatic interactions drive risk. In this paper, we detail the PoDA method and apply it to two GWAS: one of breast cancer and the other of liver cancer. The results obtained strongly suggest that there exist pathway-wide genomic differences that contribute to disease susceptibility. PoDA thus provides an analytical tool that is complementary to existing techniques and has the power to enrich our understanding of disease genomics at the systems-level.\",\"Author Summary We present a novel method for multi–SNP analysis of genome-wide association studies. The method is motivated by the intuition that, if a set of SNPs is associated with disease, cases and controls will exhibit more within-group similarity than across-group similarity for the SNPs in the set of interest. Our method, Pathways of Distinction Analysis (PoDA), uses GWAS data and known pathway–gene and gene–SNP associations to identify pathways that permit the distinction of cases from controls. By systematically applying the method to all pathways of potential interest, we can identify pathways containing SNPs for which the cases and controls are distinguished and infer those pathways\\u0027 role in disease. We detail the PoDA method and describe its results in breast and liver cancer GWAS data, demonstrating its utility as a method for systems-level analysis of GWAS data.\"],\"language\":\"eng\",\"subjects\":[\"Research Article\",\"Biology\",\"Computational Biology\",\"Genomics\",\"Population Genetics\",\"Systems Biology\",\"Genomics\",\"Genome Analysis Tools\",\"Systems Biology\"],\"creators\":[\"Braun, Rosemary\",\"Buetow, Kenneth\"],\"publicationdate\":\"2011-06-01\",\"publisher\":\"Public Library of Science\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"PLoS Genetics\",\"issn\":\"1553-7390\",\"eissn\":\"1553-7404\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1371/journal.pgen.1002101\",\"type\":\"doi\"},{\"value\":\"PMC3111473\",\"type\":\"pmc\"},{\"value\":\"21695280\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3111473\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://arxiv.org/abs/1012.4726\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://arxiv.org/abs/1012.4726\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"arXiv.org e-Print Archive\",\"url\":\"http://arxiv.org/abs/1012.4726\",\"id\":\"oai:arXiv.org:1012.4726\"},\"trust\":0.105216265}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2132315"},"target_publication_author_list":{"type":"LIST_STRING","value":["Braun, Rosemary","Buetow, Kenneth"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:arXiv.org:1012.4726"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research Article","Biology","Computational Biology","Genomics","Population Genetics","Systems Biology","Genomics","Genome Analysis Tools","Systems Biology"]},"trust":{"type":"FLOAT","value":0.105216265},"target_publication_title":{"type":"STRING","value":"Pathways of Distinction Analysis: A New Technique for Multi–SNP Analysis of GWAS Data"},"provenance_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_dateofacceptance":{"type":"DATE","value":"2011-06-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MISSING/PID","payload":"{\"publication\":{\"originalId\":\"oai:arXiv.org:1012.4726\",\"titles\":[\"Pathways of Distinction Analysis: a new technique for multi-SNP analysis of GWAS data\"],\"abstracts\":[\" Genome-wide association studies have become increasingly common due to\\nadvances in technology and have permitted the identification of differences in\\nsingle nucleotide polymorphism (SNP) alleles that are associated with diseases.\\nHowever, while typical GWAS analysis techniques treat markers individually,\\ncomplex diseases are unlikely to have a single causative gene. There is thus a\\npressing need for multi-SNP analysis methods that can reveal system-level\\ndifferences in cases and controls. Here, we present a novel multi-SNP GWAS\\nanalysis method called Pathways of Distinction Analysis (PoDA). The method uses\\nGWAS data and known pathway-gene and gene-SNP associations to identify pathways\\nthat permit, ideally, the distinction of cases from controls. The technique is\\nbased upon the hypothesis that if a pathway is related to disease risk, cases\\nwill appear more similar to other cases than to controls for the SNPs\\nassociated with that pathway. By systematically applying the method to all\\npathways of potential interest, we can identify those for which the hypothesis\\nholds true, i.e., pathways containing SNPs for which the samples exhibit\\ngreater within-class similarity than across classes. Importantly, PoDA improves\\non existing single-SNP and SNP-set enrichment analyses in that it does not\\nrequire the SNPs in a pathway to exhibit independent main effects. This permits\\nPoDA to reveal pathways in which epistatic interactions drives risk. In this\\npaper, we detail the PoDA method and apply it to two GWA studies: one of breast\\ncancer, and the other of liver cancer. The results obtained strongly suggest\\nthat there exist pathway-wide genomic differences that contribute to disease\\nsusceptibility. PoDA thus provides an analytical tool that is complementary to\\nexisting techniques and has the power to enrich our understanding of disease\\ngenomics at the systems-level.\\n\",\"Comment: Revision\"],\"language\":\"eng\",\"subjects\":[\"Quantitative Biology - Quantitative Methods\",\"Quantitative Biology - Genomics\",\"Quantitative Biology - Molecular Networks\",\"Statistics - Applications\",\"Statistics - Computation\"],\"creators\":[\"Braun, Rosemary\",\"Buetow, Kenneth\"],\"publicationdate\":\"2010-12-21\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"arXiv.org e-Print Archive\"],\"pids\":[{\"value\":\"10.1371/journal.pgen.1002101\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://arxiv.org/abs/1012.4726\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"pids\":[{\"value\":\"10.1371/journal.pgen.1002101\",\"type\":\"doi\"}]},\"provenance\":{\"repositoryName\":\"Europe PubMed Central\",\"url\":\"http://europepmc.org/articles/PMC3111473\",\"id\":\"oai:europepmc.org:2132315\"},\"trust\":0.81494087}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_publication_id":{"type":"STRING","value":"oai:arXiv.org:1012.4726"},"target_publication_author_list":{"type":"LIST_STRING","value":["Braun, Rosemary","Buetow, Kenneth"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:europepmc.org:2132315"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Quantitative Biology - Quantitative Methods","Quantitative Biology - Genomics","Quantitative Biology - Molecular Networks","Statistics - Applications","Statistics - Computation"]},"trust":{"type":"FLOAT","value":0.81494087},"target_publication_title":{"type":"STRING","value":"Pathways of Distinction Analysis: a new technique for multi-SNP analysis of GWAS data"},"provenance_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_dateofacceptance":{"type":"DATE","value":"2010-12-21"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MISSING/PID","payload":"{\"publication\":{\"originalId\":\"oai:arXiv.org:1012.4726\",\"titles\":[\"Pathways of Distinction Analysis: a new technique for multi-SNP analysis of GWAS data\"],\"abstracts\":[\" Genome-wide association studies have become increasingly common due to\\nadvances in technology and have permitted the identification of differences in\\nsingle nucleotide polymorphism (SNP) alleles that are associated with diseases.\\nHowever, while typical GWAS analysis techniques treat markers individually,\\ncomplex diseases are unlikely to have a single causative gene. There is thus a\\npressing need for multi-SNP analysis methods that can reveal system-level\\ndifferences in cases and controls. Here, we present a novel multi-SNP GWAS\\nanalysis method called Pathways of Distinction Analysis (PoDA). The method uses\\nGWAS data and known pathway-gene and gene-SNP associations to identify pathways\\nthat permit, ideally, the distinction of cases from controls. The technique is\\nbased upon the hypothesis that if a pathway is related to disease risk, cases\\nwill appear more similar to other cases than to controls for the SNPs\\nassociated with that pathway. By systematically applying the method to all\\npathways of potential interest, we can identify those for which the hypothesis\\nholds true, i.e., pathways containing SNPs for which the samples exhibit\\ngreater within-class similarity than across classes. 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Toch verdwijnt religie niet, en lijken allerlei vormen van spiritualiteit en sommige vormen van religie het goed te doen. Met andere woorden, er lijkt ook sprake te zijn van een zekere ‘sacralisering’. Deze ‘nieuwe’ vormen van religiositeit worden vaak geinterpreteerd als een antwoord op de spanningen die individualisering oproept of als resultaat van de beperkingen van het rationalisme. Dit proefschrift beschrijft en interpreteert de aard en plaats van religieuze praktijken in de lokale dorpsgemeenschappen in Zuid-Limburg op basis van veldwerk in dit gebied. Hierbij wordt vooral aandacht besteedt aan de rol van religie en spiritualiteit bij morele orientatie. Het blijkt dat de verhouding tot religieuze autoriteit wordt gekenmerkt door een sterke ambivalentie en de wens om de eigen vertrouwde wereld van familie en lokale gemeenschap te beschermen tegen inmenging van ‘vreemde’ autoriteiten. Zowel de rol van het ‘traditionele’ katholicisme als nieuwe vormen van spiritualiteit in deze gemeenschappen wordt beschreven. In duidingen van hedendaagse religiositeit is het belangrijk om deze ambivalentie ten opzichte van religieuze autoriteit niet alleen maar als ‘individualisme’ af te doen. Bovenal wenst men een vorm van religiositeit die zich makkelijk laat voegen in het domein van het vertrouwde, die de waarden die in dit domein gelden ondersteunt en manieren biedt om te reflecteren op de problemen die zich in dit domein voordoen. Hoewel individualisering en individualisme zeker belangrijk zijn, willen veel mensen toch gewoon een bepaalde continuïteit met het verleden, en verbondenheid met de directe omgeving, in dit geval de lokale dorpsgemeenschap.\",\"Droogers, A.F. 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Furthermore, there has been considerable controversy concerning the etiology of this malignancy. New studies, both clinical and molecular, strongly suggest that HGSC originates not from the surface of the ovary, but from the epithelial layer of the neighboring fallopian tube fimbriae. In this paper we summarize data supporting the central role of fallopian tube epithelium in the development of HGSC. Specifically, we address cellular pathways and regulatory mechanisms which are modulated in the process of transformation, but also genetic changes which accumulate during disease progression. Similarities between fallopian tube mucosa and the malignant tissue of HGSC warrant a closer analysis of homeostatic mechanisms in healthy epithelium in order to elucidate key steps in disease development. Finally, we highlight the importance of the cancer stem cell (CSC) identification and understanding of its niche regulation for improvement of therapeutic strategies.\"],\"language\":\"eng\",\"subjects\":[\"Review\",\"serous ovarian cancer\",\"fallopian tube\",\"p53 signature\",\"STIC\",\"cellular transformation\",\"cancer stem cells (CSC)\",\"tumor microenvironment\"],\"creators\":[\"Kessler, Mirjana\",\"Fotopoulou, Christina\",\"Meyer, Thomas\"],\"publicationdate\":\"2013-03-01\",\"publisher\":\"Molecular Diversity Preservation International (MDPI)\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"International Journal of Molecular Sciences\",\"issn\":\"\",\"eissn\":\"1422-0067\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3390/ijms14046571\",\"type\":\"doi\"},{\"value\":\"PMC3645655\",\"type\":\"pmc\"},{\"value\":\"23528888\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3645655\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.mdpi.com/1422-0067/14/4/6571\",\"license\":\"OPEN\",\"hostedby\":\"International Journal of Molecular Sciences\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.mdpi.com/1422-0067/14/4/6571\",\"license\":\"OPEN\",\"hostedby\":\"International Journal of Molecular Sciences\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.mdpi.com/1422-0067/14/4/6571\",\"id\":\"oai:doaj.org/article:13ce6672e8a04ea28e0b170acaf58241\"},\"trust\":0.06068796}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2649720"},"target_publication_author_list":{"type":"LIST_STRING","value":["Kessler, Mirjana","Fotopoulou, Christina","Meyer, Thomas"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:13ce6672e8a04ea28e0b170acaf58241"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Review","serous ovarian cancer","fallopian tube","p53 signature","STIC","cellular transformation","cancer stem cells (CSC)","tumor microenvironment"]},"trust":{"type":"FLOAT","value":0.06068796},"target_publication_title":{"type":"STRING","value":"The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2013-03-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:3614793\",\"titles\":[\"Trace Elements Speciation of Submicron Particulate Matter (PM1) Collected in the Surroundings of Power Plants\"],\"abstracts\":[\"This study reports the concentrations of PM1 trace elements (As, Cd, Co, Cr, Hg, Mn, Ni, Pb, Sb and Se) content in highly mobile (F1), mobile (F2), less mobile (F3) and not mobile (F4) fractions in samples that were collected in the surroundings of power plants in southern Poland. It also reports source identification by enrichment factors (EF) and a principal component analysis (PCA). There is limited availability of scientific data concerning the chemical composition of dust, including fractionation analyses of trace elements, in the surroundings of power plants. The present study offers important results in order to fill this data gap. The data collected in this study can be utilized to validate air quality models in this rapidly developing area. They are also crucial for comparisons with datasets from similar areas all over the world. Moreover, the identification of the bioavailability of selected carcinogenic and toxic elements in the future might be used as output data for potential biological and population research on risk assessment. This is important in the context of air pollution being hazardous to human health.\"],\"language\":\"eng\",\"subjects\":[\"Article\",\"PM1\",\"trace elements\",\"power plants\",\"chemical fractionation\",\"enrichment factor (EF)\",\"principal component analysis (PCA)\"],\"creators\":[\"Zajusz-Zubek, Elwira\",\"Kaczmarek, Konrad\",\"Mainka, Anna\"],\"publicationdate\":\"2015-10-01\",\"publisher\":\"MDPI\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"International Journal of Environmental Research and Public Health\",\"issn\":\"1661-7827\",\"eissn\":\"1660-4601\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3390/ijerph121013085\",\"type\":\"doi\"},{\"value\":\"PMC4627018\",\"type\":\"pmc\"},{\"value\":\"26501310\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4627018\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.mdpi.com/1660-4601/12/10/13085\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.mdpi.com/1660-4601/12/10/13085\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.mdpi.com/1660-4601/12/10/13085\",\"id\":\"oai:doaj.org/article:843ff8849c5d48ba86c430ffc26f495f\"},\"trust\":0.41486758}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3614793"},"target_publication_author_list":{"type":"LIST_STRING","value":["Zajusz-Zubek, Elwira","Kaczmarek, Konrad","Mainka, Anna"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:843ff8849c5d48ba86c430ffc26f495f"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Article","PM1","trace elements","power plants","chemical fractionation","enrichment factor (EF)","principal component analysis (PCA)"]},"trust":{"type":"FLOAT","value":0.41486758},"target_publication_title":{"type":"STRING","value":"Trace Elements Speciation of Submicron Particulate Matter (PM1) Collected in the Surroundings of Power Plants"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2015-10-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:library.wur.nl:wurpubs/10664\",\"titles\":[\"Photoinduced charge separation and enzyme reactions in reversed micelles.\"],\"abstracts\":[\"In this thesis the performance and coupling of two types of reaction, photoinduced charge separation and enzymatic conversion were studied in reversed micelles. Reversed micelles are 1 to 10 nm sized water droplets dispersed in an organic solution. The dispersant is a detergent (cationogenic, nonionogenic or anionogenic). In some solutions an additional compound (cosurfactant) is necessary to stabilize the droplets. In the studies presented here aliphatic alcohols were used for this purpose. The composition of reversed micelles can be optimized to yield both an efficient photoinduced charge separation and a high enzyme turnover number.In Chapter 2 a photosystem was coupled to the reduction of α-βunsaturated carboxylates by enoate reductase (EC 1.3.1.31). The photosystem was composed of a porphyrin as photosensitizer, tributylamine as electrondonor and methylviologen as electronacceptor. The photoinduced enzymatic system was active for over 100 hours. A 100% conversion could be accomplished. Systematic studies to the relation between the efficiency of the photosystem and the composition of the reversed micellar solution showed that an increase in cosurfactant concentration and cosurfactant polarity induced a higher yield of charge separation. The location of a porphyrin as a function of the composition of the reversed micellar solution was studied. The polarity of the environment of a porphyrin could very well be probed by \\u003csup\\u003e\\u003cfont size\\u003d\\\"-2\\\"\\u003e19\\u003c/font\\u003e\\u003c/SUP\\u003eF-NMR. The results showed that the porphyrin was located in the interfacial region of the reversed micelle. Modification of the porphyrin with a hexadecyl tail anchored the porphyrin. Although distinct differences between the environment and mobility of the tailed and untailed porphyrin could be detected, the efficiencies of photosystems using these porphyrins were similar. Thus neither the location, nor the mobility of the porphyrin but the concentration of alcohol in the reversed micellar solution is the main factor determining the yield of the photoinduced charge separation. An increased alcohol concentration in the medium is known to increase the flexibility of the micelles and to affect the partitioning of the electron donor. Therefore, the availability of the donor and the flexibility of the reversed micellar system have to be optimized to obtain a highly efficient photosystem. The spectroscopic properties of those porphyrins are affected by the interfacial location of the molecule. An increasing resolution of the fluorescence emission spectrum and a transient fluorescence rise in detergent solutions indicate that after excitation an intramolecular rearrangement occurs.The enzyme performance in photoinduced enzymatic reactions is determined by its stability and its activity. Increasing the chain length of the cosurfactant increased the stability of the enzyme in its oxidized state, but the stability of the reduced enzyme was lowered. The activity of enoate reductase increased with increasing cosurfactant polarity, but the relation with the concentration of cosurfactant in the reversed micellar solution was unexpected (Chapter 2). Therefore the kinetics of enoate reductase were studied in great detail using a water soluble substrate. A model was derived taking into account that both substrate supply and substrate concentration in the microheterogeneous reversed micellar solution deviate from those in aqueous solutions. Not only the, unaltered, intrinsic kinetic parameters of the enzyme, but also the reversed micellar concentration, the intramicellar substrate concentration and the rate and efficiency of the exchange of reversed micellar contents were shown to determine the enzyme activity. This model could be used to predict the experimental enoate reductase results in reversed micelles prepared with an anionogenic, a cationogenic and a nonionogenic detergent (Chapter 4.2).The enzyme kinetic study was extended to the case of 20β-hydroxysteroid dehydrogenase (EC 1.1.1.53). This enzyme catalyzes the reduction of a variety of 20β-ketosteroids. It could be demonstrated that partitioning of the substrate between the aqueous phase and the organic phase was the main factor affecting the Michaelis constant observed in reversed micelles. These results could also be interpreted with the model presented in Chapter 4.1.The implications of both the kinetic model and the study to photoinduced charge separation are discussed in Chapter 5. It was shown that the electron transfer in forward direction emerges from the triplet state of the porphyrin and strongly depends on the flexibility of the system. For further optimization the redox potentials of the components, especially that of the porphyrin, need to be considered, too. With respect to the enzymatic conversion the model presented in Chapter 4 was used to explain the dependency of enzyme activity on the cosurfactant concentration. It is stressed that because of the general validity of the principles used to derive it, the model describing the enzymatic reactions in reversed micelles can be equally applied to other microheterogeneous systems.Finally some results of this thesis are listed as guidelines to optimize photoinduced enzymatic reactions in reversed micelles.\\u003cTT\\u003e\\u003c/TT\\u003e\"],\"language\":\"eng\",\"subjects\":[\"fermentatie\",\"fermentation\",\"voedselbiotechnologie\",\"food biotechnology\",\"enzymen\",\"enzymes\",\"immobilisatie\",\"immobilization\",\"biotechnologie\",\"biotechnology\",\"chemische industrie\",\"chemical industry\",\"biochemie\",\"biochemistry\",\"Industrial Microbiology\",\"Industriële microbiologie\"],\"creators\":[\"Verhaert, R. M. D.\"],\"publicationdate\":\"1989-01-01\",\"publisher\":\"Verhaert\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Wageningen Yield\"],\"pids\":[],\"instances\":[{\"url\":\"http://edepot.wur.nl/201416\",\"license\":\"OPEN\",\"hostedby\":\"Wageningen Yield\",\"instancetype\":\"Doctoral thesis\"},{\"url\":\"http://library.wur.nl/WebQuery/wurpubs/10664\",\"license\":\"OPEN\",\"hostedby\":\"Wageningen Yield\",\"instancetype\":\"Doctoral thesis\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://library.wur.nl/WebQuery/wurpubs/10664\",\"license\":\"OPEN\",\"hostedby\":\"Wageningen Yield\",\"instancetype\":\"Doctoral thesis\"}]},\"provenance\":{\"repositoryName\":\"NARCIS\",\"url\":\"http://library.wur.nl/WebQuery/wurpubs/10664\",\"id\":\"wur:oai:library.wur.nl:wurpubs/10664\"},\"trust\":0.27768385}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Wageningen Yield"},"target_publication_id":{"type":"STRING","value":"oai:library.wur.nl:wurpubs/10664"},"target_publication_author_list":{"type":"LIST_STRING","value":["Verhaert, R. M. D."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["wur:oai:library.wur.nl:wurpubs/10664"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::fdb035c8b3e0540a8d9a561a6c44f4de"},"target_publication_subject_list":{"type":"LIST_STRING","value":["fermentatie","fermentation","voedselbiotechnologie","food biotechnology","enzymen","enzymes","immobilisatie","immobilization","biotechnologie","biotechnology","chemische industrie","chemical industry","biochemie","biochemistry","Industrial Microbiology","Industriële microbiologie"]},"trust":{"type":"FLOAT","value":0.27768385},"target_publication_title":{"type":"STRING","value":"Photoinduced charge separation and enzyme reactions in reversed micelles."},"provenance_datasource_name":{"type":"STRING","value":"NARCIS"},"target_dateofacceptance":{"type":"DATE","value":"1989-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::d709f38ef758b5066ef31b18039b8ce5"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:1981481\",\"titles\":[\"Dietary taurine intake, nutrients intake, dietary habits and life stress by depression in Korean female college students: a case-control study\"],\"abstracts\":[\"Background The purpose of this study was to investigate the dietary taurine intake, nutrients intake, dietary habits and life stress by depression in Korean female college students. Methods In this study, research data were collected in March 2009 and 65 patients with depression and 65 controls without depression participated. The CES-D (Center for Epidemiologic Studies Depression) scale was used for depression measure and controls were matched for age. A 3-day recall method was used for dietary assessment (2 weekdays and 1 weekend day). Results Average height, weight and body mass index (BMI) were 161.3±0.5cm, 55.3±1.0kg and 21.2±0.4kg/m2 for depression patients and those of control group were 161.4±0.7cm, 53.1±0.8kg and 20.3±0.2kg/m2, respectively. Average dietary taurine intakes of depression patients and control group were 89.1 and 88.0 mg/day, respectively. There was no significant difference in dietary taurine intake between depression patients and control group. The average intakes of vitamin A (p\\u003c0.05), β-carotene (p\\u003c0.01), vitamin C (p\\u003c0.05), folic acid (p\\u003c0.05) and fiber (p\\u003c0.05) of depression patients were significantly lower compared to control group. The average total dietary habit score of depression patients (47.2) was significantly lower than that of control group (51.3) (p\\u003c0.01). The average dietary habit scores of “eating meals at regular times” (p\\u003c0.05), “eating adequate amount of meals” (p\\u003c0.05), “having meals with diverse foods” (p\\u003c0.05), “avoiding eating spicy foods” (p\\u003c0.01) and “eating protein foods such as meat, fish, eggs, beans more than 2 times a day” (p\\u003c0.05) were significantly lower in depression patients compare to control group. The average scores of total life stress (p\\u003c0.001) and all stress categories of depression patients were significantly higher than those of control group except faculty problem score. Conclusions These results show that depression patients have poor dietary habits and unbalanced nutrition status. Also depression patients have higher life stress score. Therefore, continuous nutrition education and counselling for good dietary habits and balanced nutrition status are needed to prevent depression in Korean college students.\"],\"language\":\"eng\",\"subjects\":[\"Research\"],\"creators\":[\"Park, Ji-Yeon\",\"You, Jeong-Soon\",\"Chang, Kyung-Ja\"],\"publicationdate\":\"2010-08-01\",\"publisher\":\"BioMed Central\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Journal of Biomedical Science\",\"issn\":\"1021-7770\",\"eissn\":\"1423-0127\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.1186/1423-0127-17-S1-S40\",\"type\":\"doi\"},{\"value\":\"PMC2994399\",\"type\":\"pmc\"},{\"value\":\"20804617\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC2994399\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.biomedcentral.com/content/pdf/1423-0127-17-S1-info.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Journal of Biomedical Science\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.biomedcentral.com/content/pdf/1423-0127-17-S1-info.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Journal of Biomedical Science\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.biomedcentral.com/content/pdf/1423-0127-17-S1-info.pdf\",\"id\":\"oai:doaj.org/article:f70239928066429e913960fac1e6ad67\"},\"trust\":0.5491964}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:1981481"},"target_publication_author_list":{"type":"LIST_STRING","value":["Park, Ji-Yeon","You, Jeong-Soon","Chang, Kyung-Ja"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:f70239928066429e913960fac1e6ad67"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Research"]},"trust":{"type":"FLOAT","value":0.5491964},"target_publication_title":{"type":"STRING","value":"Dietary taurine intake, nutrients intake, dietary habits and life stress by depression in Korean female college students: a case-control study"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2010-08-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:europepmc.org:2325748\",\"titles\":[\"Prescribing gliptins: Enthusiasm should be coupled with caution\"],\"abstracts\":[],\"language\":\"eng\",\"subjects\":[\"Letters to the Editor\"],\"creators\":[\"Garg, M. K.\",\"Kharb, Sandeep\",\"Pandit, Aditi\"],\"publicationdate\":\"2012-01-01\",\"publisher\":\"Medknow Publications \\u0026 Media Pvt Ltd\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Indian Journal of Endocrinology and Metabolism\",\"issn\":\"2230-8210\",\"eissn\":\"2230-9500\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.4103/2230-8210.93785\",\"type\":\"doi\"},{\"value\":\"PMC3313765\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC3313765\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.ijem.in/article.asp?issn\\u003d2230-8210;year\\u003d2012;volume\\u003d16;issue\\u003d2;spage\\u003d324;epage\\u003d325;aulast\\u003dGarg\",\"license\":\"OPEN\",\"hostedby\":\"Indian Journal of Endocrinology and Metabolism\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.ijem.in/article.asp?issn\\u003d2230-8210;year\\u003d2012;volume\\u003d16;issue\\u003d2;spage\\u003d324;epage\\u003d325;aulast\\u003dGarg\",\"license\":\"OPEN\",\"hostedby\":\"Indian Journal of Endocrinology and Metabolism\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.ijem.in/article.asp?issn\\u003d2230-8210;year\\u003d2012;volume\\u003d16;issue\\u003d2;spage\\u003d324;epage\\u003d325;aulast\\u003dGarg\",\"id\":\"oai:doaj.org/article:2307f76950984a13be26d3495ec95aa6\"},\"trust\":0.2600354}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:2325748"},"target_publication_author_list":{"type":"LIST_STRING","value":["Garg, M. 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Current methods have extracted feature information at different levels, among which the characteristic stem-loop structure makes the greatest contribution to the prediction of putative miRNA precursor (pre-miRNA). We find that none of these features alone is capable of identifying new pre-miRNA accurately. Results In the present work, a pre-miRNA stem-loop secondary structure is translated to a network, which provides a novel perspective for its structural analysis. Network parameters are used to construct prediction model, achieving an area under the receiver operating curves (AUC) value of 0.956. Moreover, by repeating the same method on two independent datasets, accuracies of 0.976 and 0.913 are achieved, respectively. Conclusions Network parameters effectively characterize pre-miRNA secondary structure, which improves our prediction model in both prediction ability and computation efficiency. 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Results show that there are cases that institutional quality influences positively or negatively the individual effects of specific types of business regulation on bank performance.\"],\"language\":\"und\",\"subjects\":[\"regulation of business; bank performance; European Union.\"],\"creators\":[\"Mamatzakis, E.\"],\"publicationdate\":\"2014-11-14\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Research Papers in Economics\"],\"pids\":[],\"instances\":[{\"url\":\"https://mpra.ub.uni-muenchen.de/60200/1/MPRA_paper_60200.pdf\",\"license\":\"OPEN\",\"hostedby\":\"Research Papers in Economics\",\"instancetype\":\"Preprint\"},{\"url\":\"https://mpra.ub.uni-muenchen.de/60200/\",\"license\":\"OPEN\",\"hostedby\":\"Munich RePEc Personal Archive\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://mpra.ub.uni-muenchen.de/60200/\",\"license\":\"OPEN\",\"hostedby\":\"Munich RePEc Personal Archive\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"Munich RePEc Personal Archive\",\"url\":\"https://mpra.ub.uni-muenchen.de/60200/\",\"id\":\"60200\"},\"trust\":0.58711904}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Research Papers in Economics"},"target_publication_id":{"type":"STRING","value":"oai:RePEc:pra:mprapa:60200"},"target_publication_author_list":{"type":"LIST_STRING","value":["Mamatzakis, E."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["60200"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::7501e5d4da87ac39d782741cd794002d"},"target_publication_subject_list":{"type":"LIST_STRING","value":["regulation of business; bank performance; European Union."]},"trust":{"type":"FLOAT","value":0.58711904},"target_publication_title":{"type":"STRING","value":"Does Business Regulation Matter for Banks in the European Union?"},"provenance_datasource_name":{"type":"STRING","value":"Munich RePEc Personal Archive"},"target_dateofacceptance":{"type":"DATE","value":"2014-11-14"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::5e9f92a01c986bafcabbafd145520b13"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:RePEc:sbs:wpsefe:1999fe09\",\"titles\":[\"Finance, Investment and Growth\"],\"abstracts\":[\"This paper evaluates relations between industrial activity and the structure of countries’ financial, ownership and legal systems. Using data on 27 industries in 14 OECD countries over the period 1970 to 1995, we evaluate whether the structure of countries’ systems is associated with different types of economic activity. We do this by examining whether there is a link between industry activity and the interaction of country structures with industry characteristics. We find that there is a relation in terms of both industry growth rates and shares of output devoted to R\\u0026D. Investment in R\\u0026D rather than fixed capital formation appears to be the main route through which financial systems affect economic activity. Consistent with theories of financial development, relations between financial systems and economic activity are sensitive to countries’ stages of economic development. 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Using data on 27 industries in 14 OECD countries over the period 1970 to 1995, we evaluate whether the structure of countries\\u0027 systems is associated with different types of economic activity. We do this by examining whether there is a link between industry activity and the interaction of country structures with industry characteristics. We find that there is a relation in terms of both industry growth rates and shares of output devoted to R\\u0026D. Investment in R\\u0026D rather than fixed capital formation appears to be the main route through which financial systems affect economic activity. Consistent with theories of financial development, relations between financial systems and economic activity are sensitive to countries\\u0027 stages of economic development. 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The use of nanoparticles in medicine has brought about the issue of their interaction with the immune system for two main reasons: first, understanding how long nanomedicines could persist in the organism and exert their beneficial effects before being recognized and eliminated by our defensive systems; second, understanding how the immune responses can be modulated by nanoparticles in order to obtain optimal effects. This issue is crucial in vaccine formulations based on the use of nanoparticles, which can operate both as a delivery system to enhance antigen processing and as an immunostimulatory adjuvant to induce and amplify protective immunity, in part because of their ability to activate the inflammasome and induce the maturation of interleukin 1β. Nanoparticles can be excellent adjuvants due to their biocompatibility and their physicochemical properties (e.g., size, shape, and surface charge), which can be tailored to obtain different immunological effects. This review provides an overview of recent strategies for the use of nanoparticles as promising/attractive adjuvants for novel prophylactic and therapeutic vaccines. The use of nanovaccines, with their practically infinite possibilities of specific design, could open the way to precision vaccinology, i.e., vaccine formulations tailored on the individual immune reactivity status.\"],\"language\":\"eng\",\"subjects\":[\"Review\",\"nanoparticles\",\"vaccines\",\"adjuvants\",\"inflammation\"],\"creators\":[\"Boraschi, Diana\",\"Italiani, Paola\"],\"publicationdate\":\"2015-11-01\",\"publisher\":\"MDPI\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Vaccines\",\"issn\":\"\",\"eissn\":\"2076-393X\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3390/vaccines3040930\",\"type\":\"doi\"},{\"value\":\"PMC4693225\",\"type\":\"pmc\"},{\"value\":\"26556378\",\"type\":\"pmid\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4693225\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://www.mdpi.com/2076-393X/3/4/930\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://www.mdpi.com/2076-393X/3/4/930\",\"license\":\"OPEN\",\"hostedby\":\"DOAJ-Articles\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"DOAJ-Articles\",\"url\":\"http://www.mdpi.com/2076-393X/3/4/930\",\"id\":\"oai:doaj.org/article:4397cb2fde99432aac0fcc2e5202a6fe\"},\"trust\":0.25508696}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3680197"},"target_publication_author_list":{"type":"LIST_STRING","value":["Boraschi, Diana","Italiani, Paola"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:doaj.org/article:4397cb2fde99432aac0fcc2e5202a6fe"]},"provenance_datasource_id":{"type":"STRING","value":"10|driver______::bee53aa31dc2cbb538c10c2b65fa5824"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Review","nanoparticles","vaccines","adjuvants","inflammation"]},"trust":{"type":"FLOAT","value":0.25508696},"target_publication_title":{"type":"STRING","value":"From Antigen Delivery System to Adjuvanticy: The Board Application of Nanoparticles in Vaccinology"},"provenance_datasource_name":{"type":"STRING","value":"DOAJ-Articles"},"target_dateofacceptance":{"type":"DATE","value":"2015-11-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:library.wur.nl:wurpubs/426284\",\"titles\":[\"Water balance and energy partitioning in a semi-closed greenhouse\"],\"abstracts\":[\"The concept of a closed (or semi-closed) greenhouse that is used to harvest solar energy can be attractive to reduce the fossil fuel input or for an increment of water use efficiency. To examine the concept, a 550 m2 greenhouse was built in The Netherlands and experiments were carried out with a pepper crop. This paper reports only on the water balance during the summer period of such a greenhouse and examines the energy partitioning of the solar radiation in the greenhouse. Results show that the percentage of drainage out of the irrigation changed significantly among the days but was on average 34%. The major water input to the greenhouse came from irrigation and only a small fraction was due to fogging in some of the days. The remainder of irrigation minus drainage was transpired by the plants. On average, 15% of the water was lost from the greenhouse by exchange of vapor with the outside air. This was partly by leakage, but also deliberately when the greenhouse was ventilated with outside air to remove a moisture excess during night. The rest condensed, mainly on the heat exchangers of the cooling units, but partly on the roof and side walls as well. Thus, roughly 85% of water used for irrigation was recaptured. The results further show that the global radiation inside the greenhouse was on average 0.57±0.06 of the outside radiation. The heat load on the greenhouse was mainly removed by the overhead cooling units who removed sensible and latent heat with an average sensible to latent ratio of 0.62. This ratio changed among the days and increased approximately linearly with solar radiation. The energy extracted by the coolers was about 0.73±0.18 of the solar radiation entering the greenhouse, which means that it was 42% on average of the outside solar radiation.\"],\"language\":\"eng\",\"subjects\":[\"WUR GTB Tuinbouw Technologie\",\"WUR GTB Tuinbouw Technologie\"],\"creators\":[\"Teitel, M.\",\"Zwart, H. F.\",\"Kempkes, F. L. 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This graph parameter is motivated by its\\nrelevance to the problem of finding low rank solutions to semidefinite programs\\nover the elliptope, and also by its relevance to the bounded rank Grothendieck\\nconstant. Indeed, $\\\\egd(G)\\\\le r$ if and only if the rank-$r$ Grothendieck\\nconstant of $G$ is equal to 1. We show that the parameter $\\\\egd(G)$ is minor\\nmonotone, we identify several classes of forbidden minors for $\\\\egd(G)\\\\le r$\\nand we give the full characterization for the case $r\\u003d2$. We also show an upper\\nbound for $\\\\egd(G)$ in terms of a new tree-width-like parameter $\\\\sla(G)$,\\ndefined as the smallest $r$ for which $G$ is a minor of the strong product of a\\ntree and $K_r$. We show that, for any 2-connected graph $G\\\\ne K_{3,3}$ on at\\nleast 6 nodes, $\\\\egd(G)\\\\le 2$ if and only if $\\\\sla(G)\\\\le 2$.\\n\",\"Comment: 33 pages, 8 Figures. In its second version, the paper has been\\n modified to accommodate the suggestions of the referees. Furthermore, the\\n title has been changed since we feel that the new title reflects more\\n accurately the content and the main results of the paper\"],\"language\":\"eng\",\"subjects\":[\"Mathematics - Combinatorics\",\"Computer Science - Discrete Mathematics\",\"Mathematics - Optimization and Control\"],\"creators\":[\"Eisenberg-Nagy, Marianna\",\"Laurent, Monique\",\"Varvitsiotis, Antonios\"],\"publicationdate\":\"2012-05-09\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"arXiv.org e-Print Archive\"],\"pids\":[],\"instances\":[{\"url\":\"http://arxiv.org/abs/1205.2040\",\"license\":\"OPEN\",\"hostedby\":\"arXiv.org e-Print Archive\",\"instancetype\":\"Article\"},{\"url\":\"http://repository.cwi.nl/noauth/search/fullrecord.php?publnr\\u003d22773\",\"license\":\"OPEN\",\"hostedby\":\"Repository CWI Amsterdam\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://repository.cwi.nl/noauth/search/fullrecord.php?publnr\\u003d22773\",\"license\":\"OPEN\",\"hostedby\":\"Repository CWI Amsterdam\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"NARCIS\",\"url\":\"http://repository.cwi.nl/noauth/search/fullrecord.php?publnr\\u003d22773\",\"id\":\"cwi:oai:cwi.nl:22773\"},\"trust\":0.47669643}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"arXiv.org e-Print Archive"},"target_publication_id":{"type":"STRING","value":"oai:arXiv.org:1205.2040"},"target_publication_author_list":{"type":"LIST_STRING","value":["Eisenberg-Nagy, Marianna","Laurent, Monique","Varvitsiotis, Antonios"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["cwi:oai:cwi.nl:22773"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::fdb035c8b3e0540a8d9a561a6c44f4de"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Mathematics - Combinatorics","Computer Science - Discrete Mathematics","Mathematics - Optimization and Control"]},"trust":{"type":"FLOAT","value":0.47669643},"target_publication_title":{"type":"STRING","value":"Forbidden minor characterizations for low-rank optimal solutions to semidefinite programs over the elliptope"},"provenance_datasource_name":{"type":"STRING","value":"NARCIS"},"target_dateofacceptance":{"type":"DATE","value":"2012-05-09"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::6f4922f45568161a8cdf4ad2299f6d23"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:arXiv.org:0912.1116\",\"titles\":[\"Steady state fluctuation relations for systems driven by an external random force\"],\"abstracts\":[\" We experimentally study the fluctuations of the work done by an external\\nGaussian random force on two different stochastic systems coupled to a thermal\\nbath: a colloidal particle in an optical trap and an atomic force microscopy\\ncantilever. We determine the corresponding probability density functions for\\ndifferent random forcing amplitudes ranging from a small fraction to several\\ntimes the amplitude of the thermal noise. In both systems for sufficiently weak\\nforcing amplitudes the work fluctuations satisfy the usual steady state\\nfluctuation theorem. As the forcing amplitude drives the system far from\\nequilibrium, deviations of the fluctuation theorem increase monotonically. 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Epub 2007 Oct 22.\\n\\nThird-generation nephrectomy by natural orifice transluminal endoscopic surgery.\\nLima E, Rolanda C, Pêgo JM, Henriques-Coelho T, Silva D, Osório L, Moreira I, Carvalho JL, Correia-Pinto J.\\n\\nLife and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal.\\n\\nAbstract\\nPURPOSE: Recently there has been increasing enthusiasm for performing simple abdominal procedures by transgastric surgery. We previously reported the usefulness of a combined transgastric and transvesical approach to cholecystectomy. In this study we assessed the feasibility of combined transgastric and transvesical approach for performing a more complex surgical procedure, such as nephrectomy, in a porcine model.\\n\\nMATERIALS AND METHODS: In a nonsurvival study combined transgastric and transvesical approaches were established in 6 female pigs. Under ureteroscope guidance we installed a transvesical 5 mm over tube into the peritoneal cavity and a flexible gastroscope was passed orally into the peritoneal cavity by a gastrotomy. We performed right or left nephrectomy with instruments introduced by the 2 devices that worked in the renal hilum, alternating device intervention for dissection and retraction procedures.\\n\\nRESULTS: Four right and 2 left nephrectomies were performed. There were no complications during the creation of transvesical and transgastric access. In all animals we visualized the 2 kidneys. The renal vessels and ureter were reasonably individualized and ligated separately with ultrasonic scissors, which were introduced through the transvesical port. In 2 early cases mild hemorrhage occurred after ultrasonic ligation. To overcome this complication we applied clips successfully before ultrasonic ligation in the remaining animals. Thus, complete renal release and mobilization to the stomach were achieved in all animals.\\n\\nCONCLUSIONS: Nephrectomy by natural orifices using the combined transgastric and transvesical approach is technically feasible, although to our knowledge there is no reliable method for removing the specimen with current instruments.\\n\\nPMID: 17945287 [PubMed - indexed for MEDLINE]\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Lima, E.\",\"Rolanda, C.\",\"Pêgo, J. M.\",\"Henriques‐coelho, T.\",\"Silva, D.\",\"Osório, L.\",\"Moreira, I.\",\"Carvalho, J. L.\",\"Correia‐pinto, J.\"],\"publicationdate\":\"2007-12-01\",\"publisher\":\"Elsevier\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Repositório Científico do Centro Hospitalar do Porto\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10400.16/557\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Científico do Centro Hospitalar do Porto\",\"instancetype\":\"Article\"},{\"url\":\"http://comum.rcaap.pt/handle/123456789/2323\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://comum.rcaap.pt/handle/123456789/2323\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Comum\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Repositório Comum\",\"url\":\"http://comum.rcaap.pt/handle/123456789/2323\",\"id\":\"oai:comum.rcaap.pt:123456789/2323\"},\"trust\":0.17307484}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Repositório Científico do Centro Hospitalar do Porto"},"target_publication_id":{"type":"STRING","value":"oai:repositorio.chporto.pt:10400.16/557"},"target_publication_author_list":{"type":"LIST_STRING","value":["Lima, E.","Rolanda, C.","Pêgo, J. 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We previously reported the usefulness of a combined transgastric and transvesical approach to cholecystectomy. In this study we assessed the feasibility of combined transgastric and transvesical approach for performing a more complex surgical procedure, such as nephrectomy, in a porcine model.MATERIALS AND METHODS:In a nonsurvival study combined transgastric and transvesical approaches were established in 6 female pigs. Under ureteroscope guidance we installed a transvesical 5 mm over tube into the peritoneal cavity and a flexible gastroscope was passed orally into the peritoneal cavity by a gastrotomy. We performed right or left nephrectomy with instruments introduced by the 2 devices that worked in the renal hilum, alternating device intervention for dissection and retraction procedures.RESULTS:Four right and 2 left nephrectomies were performed. There were no complications during the creation of transvesical and transgastric access. In all animals we visualized the 2 kidneys. The renal vessels and ureter were reasonably individualized and ligated separately with ultrasonic scissors, which were introduced through the transvesical port. In 2 early cases mild hemorrhage occurred after ultrasonic ligation. To overcome this complication we applied clips successfully before ultrasonic ligation in the remaining animals. Thus, complete renal release and mobilization to the stomach were achieved in all animals.CONCLUSIONS:Nephrectomy by natural orifices using the combined transgastric and transvesical approach is technically feasible, although to our knowledge there is no reliable method for removing the specimen with current instruments.\"],\"language\":\"eng\",\"subjects\":[],\"creators\":[\"Lima, E.\",\"Rolanda, C.\",\"Pêgo, Jm\",\"Henriques-Coelho, T.\",\"Silva, D.\",\"Osório, L.\",\"Moreira, I.\",\"Carvalho, Jl\",\"Correia-Pinto, J.\"],\"publicationdate\":\"2007-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[\"Faculdade de Medicina\"],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"Repositório Aberto da Universidade do Porto\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10216/67144\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Aberto da Universidade do Porto\",\"instancetype\":\"Article\"},{\"url\":\"http://hdl.handle.net/10400.16/557\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Científico do Centro Hospitalar do Porto\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10400.16/557\",\"license\":\"OPEN\",\"hostedby\":\"Repositório Científico do Centro Hospitalar do Porto\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Repositório Científico do Centro Hospitalar do Porto\",\"url\":\"http://hdl.handle.net/10400.16/557\",\"id\":\"oai:repositorio.chporto.pt:10400.16/557\"},\"trust\":0.058757663}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Repositório Aberto da Universidade do Porto"},"target_publication_id":{"type":"STRING","value":"oai:repositorio-aberto.up.pt:10216/67144"},"target_publication_author_list":{"type":"LIST_STRING","value":["Lima, E.","Rolanda, C.","Pêgo, Jm","Henriques-Coelho, T.","Silva, D.","Osório, L.","Moreira, I.","Carvalho, Jl","Correia-Pinto, J."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:repositorio.chporto.pt:10400.16/557"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::777669af68dbccabc30c3b6bcaa81825"},"trust":{"type":"FLOAT","value":0.058757663},"target_publication_title":{"type":"STRING","value":"Third-generation nephrectomy by natural orifice transluminal endoscopic surgery"},"provenance_datasource_name":{"type":"STRING","value":"Repositório Científico do Centro Hospitalar do Porto"},"target_dateofacceptance":{"type":"DATE","value":"2007-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::b7087c1f4f89e63af8d46f3b20271153"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:repositorio-aberto.up.pt:10216/67144\",\"titles\":[\"Third-generation nephrectomy by natural orifice transluminal endoscopic surgery\"],\"abstracts\":[\"PURPOSE:Recently there has been increasing enthusiasm for performing simple abdominal procedures by transgastric surgery. 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In all animals we visualized the 2 kidneys. The renal vessels and ureter were reasonably individualized and ligated separately with ultrasonic scissors, which were introduced through the transvesical port. In 2 early cases mild hemorrhage occurred after ultrasonic ligation. To overcome this complication we applied clips successfully before ultrasonic ligation in the remaining animals. 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In all animals we visualized the 2 kidneys. The renal vessels and ureter were reasonably individualized and ligated separately with ultrasonic scissors, which were introduced through the transvesical port. In 2 early cases mild hemorrhage occurred after ultrasonic ligation. To overcome this complication we applied clips successfully before ultrasonic ligation in the remaining animals. 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We have previously shown that this response is dependent on ataxia telangiectasia-mutated and Rad3-related kinase and involves recruitment of DNA repair proteins into foci associated with AAV2 DNA. Here, we investigated whether recombinant AAV2 (rAAV2) vectors are able to produce a similar response. Surprisingly, the results show that both single-stranded and double-stranded green fluorescent protein-expressing rAAV2 vectors are defective in producing such a response. We show that the DNA damage signaling initiated by AAV2 was not due to the virus-encoded Rep or viral capsid proteins. UV-inactivated AAV2 induced a response similar to that of untreated AAV2. This type of DNA damage response was not provoked by other DNA molecules, such as single-stranded bacteriophage M13 or plasmid DNAs. 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Although previous work suggests that older adults learn novel motor tasks slower and to a lesser extent than younger adults, we have recently demonstrated no significant effect of chronological age on the rates and amounts of skill acquisition, nor on its long-term retention, in adults over the age of 65. To better understand predictors of skill acquisition in non-demented older adults, we now explore the relationship between early improvements in motor performance due to practice (i.e., rapid responsiveness) and longer-term retention of an upper extremity motor skill, and whether the extent of rapid responsiveness was associated with global cognitive status. Results showed significant improvements in motor performance within the first five (of 150) trials, and that this “rapid responsiveness” was predictive of skill retention 1 month later. Notably, the extent of rapid responsiveness was not dependent on global cognitive status, as measured by the Montreal Cognitive Assessment (MoCA). Thus, rapid responsiveness appears to be an important variable in longer-term neurorehabilitative efforts with older adults, regardless of their cognitive status.\"],\"language\":\"eng\",\"subjects\":[\"Neuroscience\",\"Original Research\",\"motor skill\",\"learning\",\"practice effects\",\"retention\",\"cognition\"],\"creators\":[\"Schaefer, Sydney Y.\",\"Duff, Kevin\"],\"publicationdate\":\"2015-11-01\",\"publisher\":\"Frontiers Media S.A.\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"Frontiers in Aging Neuroscience\",\"issn\":\"\",\"eissn\":\"1663-4365\",\"lissn\":\"\"},\"collectedFrom\":[\"Europe PubMed Central\"],\"pids\":[{\"value\":\"10.3389/fnagi.2015.00214\",\"type\":\"doi\"},{\"value\":\"PMC4649025\",\"type\":\"pmc\"}],\"instances\":[{\"url\":\"http://europepmc.org/articles/PMC4649025\",\"license\":\"OPEN\",\"hostedby\":\"Europe PubMed Central\",\"instancetype\":\"Article\"},{\"url\":\"http://dx.doi.org/10.3389/fnagi.2015.00214\",\"license\":\"OPEN\",\"hostedby\":\"Frontiers in Aging Neuroscience\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://dx.doi.org/10.3389/fnagi.2015.00214\",\"license\":\"OPEN\",\"hostedby\":\"Frontiers in Aging Neuroscience\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"Frontiers\",\"url\":\"http://dx.doi.org/10.3389/fnagi.2015.00214\",\"id\":\"10.3389/fnagi.2015.00214\"},\"trust\":0.41783154}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"Europe PubMed Central"},"target_publication_id":{"type":"STRING","value":"oai:europepmc.org:3643948"},"target_publication_author_list":{"type":"LIST_STRING","value":["Schaefer, Sydney Y.","Duff, Kevin"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["10.3389/fnagi.2015.00214"]},"provenance_datasource_id":{"type":"STRING","value":"10|openaire____::3db634fc5446f389d0b826ea400a5da6"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Neuroscience","Original Research","motor skill","learning","practice effects","retention","cognition"]},"trust":{"type":"FLOAT","value":0.41783154},"target_publication_title":{"type":"STRING","value":"Rapid Responsiveness to Practice Predicts Longer-Term Retention of Upper Extremity Motor Skill in Non-Demented Older Adults"},"provenance_datasource_name":{"type":"STRING","value":"Frontiers"},"target_dateofacceptance":{"type":"DATE","value":"2015-11-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::8b6dd7db9af49e67306feb59a8bdc52c"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:hal.archives-ouvertes.fr:jpa-00222588\",\"titles\":[\"APPLICATIONS OF DEGENERATE FOUR-WAVE MIXING TO HIGH RESOLUTION MOLECULAR SPECTROSCOPY AT 10.6 µm\"],\"abstracts\":[\"CW phase conjugation on the ν3 vibrational bands of SF6 and OsO4 is demonstrated as a means of investigation in high resolution spectroscopy through resonant degenerate four-wave mixing at 10.6 µm by using a stable low power CO2 laser operating on the P(18), P(16), P(12) lines respectively. Peak reflectivities of 3.8 10-3 are measured in SF6. They only reach 0.34 10-3 in OsO4. Phase conjugate spectra with 2 MHz, namely sub-Doppler resolutions, are compared with simultaneous recordings of the saturated-absorption spectra over a 80 MHz bandwidth. The saturation splitting encountered on a one-photon transition in SF6 is also analysed in terms of pressure broadening and pump imbalance.\"],\"language\":\"eng\",\"subjects\":[\"[PHYS:HIST] Physics/Physics archives\",\"[PHYS:HIST] Physique/Articles anciens\"],\"creators\":[\"Boulnois, J.\"],\"publicationdate\":\"1983-01-01\",\"publisher\":\"\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"INRIA a CCSD electronic archive server\"],\"pids\":[{\"value\":\"10.1051/jphyscol:1983216\",\"type\":\"doi\"}],\"instances\":[{\"url\":\"http://hal.archives-ouvertes.fr/jpa-00222588\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Article\"},{\"url\":\"https://hal.archives-ouvertes.fr/jpa-00222588\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"https://hal.archives-ouvertes.fr/jpa-00222588\",\"license\":\"OPEN\",\"hostedby\":\"INRIA a CCSD electronic archive server\",\"instancetype\":\"Unknown\"}]},\"provenance\":{\"repositoryName\":\"INRIA a CCSD electronic archive server\",\"url\":\"https://hal.archives-ouvertes.fr/jpa-00222588\",\"id\":\"oai:HAL:jpa-00222588v1\"},\"trust\":0.9570215}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_publication_id":{"type":"STRING","value":"oai:hal.archives-ouvertes.fr:jpa-00222588"},"target_publication_author_list":{"type":"LIST_STRING","value":["Boulnois, J."]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:HAL:jpa-00222588v1"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"},"target_publication_subject_list":{"type":"LIST_STRING","value":["[PHYS:HIST] Physics/Physics archives","[PHYS:HIST] Physique/Articles anciens"]},"trust":{"type":"FLOAT","value":0.9570215},"target_publication_title":{"type":"STRING","value":"APPLICATIONS OF DEGENERATE FOUR-WAVE MIXING TO HIGH RESOLUTION MOLECULAR SPECTROSCOPY AT 10.6 µm"},"provenance_datasource_name":{"type":"STRING","value":"INRIA a CCSD electronic archive server"},"target_dateofacceptance":{"type":"DATE","value":"1983-01-01"},"target_datasource_id":{"type":"STRING","value":"10|opendoar____::9766527f2b5d3e95d4a733fcfb77bd7e"}}} {"producerId":"OpenAIRE","topic":"ENRICH/MORE/OPENACCESS_VERSION","payload":"{\"publication\":{\"originalId\":\"oai:HAL:jpa-00222588v1\",\"titles\":[\"APPLICATIONS OF DEGENERATE FOUR-WAVE MIXING TO HIGH RESOLUTION MOLECULAR SPECTROSCOPY AT 10.6 µm\"],\"abstracts\":[\"CW phase conjugation on the ν3 vibrational bands of SF6 and OsO4 is demonstrated as a means of investigation in high resolution spectroscopy through resonant degenerate four-wave mixing at 10.6 µm by using a stable low power CO2 laser operating on the P(18), P(16), P(12) lines respectively. Peak reflectivities of 3.8 10-3 are measured in SF6. They only reach 0.34 10-3 in OsO4. Phase conjugate spectra with 2 MHz, namely sub-Doppler resolutions, are compared with simultaneous recordings of the saturated-absorption spectra over a 80 MHz bandwidth. 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Br. (Poaceae) en la Península Ibérica\"],\"abstracts\":[\"[ES] En la Península Ibérica se reconocen cuatro especies del género Glyceria R. Br. cuyas pautas de distribución se relacionan con diferentes factores mesológicos como son el clima y la naturaleza química del sustrato. G. notata ocupa la vertiente oriental mayoritariamente constituida por sustratos ricos en bases. G. fluitans muestra una distribución occidental-septentrional preferentemente en territorios con macrobioclima templado. G. declinata encuentra su mayor extensión en el occidente, sobre sustratos pobres en bases, en áreas de macrobioclima mediterráneo. Por último, G. spicata se encuentra restringida a los territorios cálidos sur-occidentales con macrobioclima mediterráneo donde el género Glyceria alcanza la más alta densidad de especies en la Península Ibérica.\",\"[EN] Four species belonging to the genus Glyceria R. Br. are recognized in the Iberian Peninsula. Their patterns of distribution are related with different mesological features as climate and substrate. G. notata occurs in the half eastern part of Iberian Peninsula wich is mainly constituted by base-rich substrates. G. fluitans shows a western and northerly distribution on chiefly temperate macrobioclimate areas. G declinata reaches its greater extension in the West of the Iberian Peninsula on base-poor substrates within the mediterranean macrobioclimate. Finally, G. spicata is restricted to the Southerwestern warmer territories with a mediterranean macrobioclimate where the genus Glyceria reaches the greatest density of species in the Iberian Peninsula.\"],\"language\":\"esl/spa\",\"subjects\":[\"Botánica\",\"Plantas medicinales\",\"Botany\",\"Medicinal plants\"],\"creators\":[\"Molina Abril, José Antonio\",\"Pertíñez Izquierdo, Concepción\"],\"publicationdate\":\"2009-12-16\",\"publisher\":\"Ediciones Universidad de Salamanca (España)\",\"embargoenddate\":\"\",\"contributor\":[],\"journal\":{\"name\":\"\",\"issn\":\"\",\"eissn\":\"\",\"lissn\":\"\"},\"collectedFrom\":[\"GREDOS\"],\"pids\":[],\"instances\":[{\"url\":\"http://hdl.handle.net/10366/73939\",\"license\":\"OPEN\",\"hostedby\":\"GREDOS\",\"instancetype\":\"Article\"},{\"url\":\"http://hdl.handle.net/10366/73939\",\"license\":\"OPEN\",\"hostedby\":\"GREDOS\",\"instancetype\":\"Article\"}],\"externalReferences\":[]},\"highlight\":{\"instances\":[{\"url\":\"http://hdl.handle.net/10366/73939\",\"license\":\"OPEN\",\"hostedby\":\"GREDOS\",\"instancetype\":\"Article\"}]},\"provenance\":{\"repositoryName\":\"GREDOS\",\"url\":\"http://hdl.handle.net/10366/73939\",\"id\":\"oai:gredos.usal.es:10366/73939\"},\"trust\":0.7826948}","tthDays":0,"map":{"target_datasource_name":{"type":"STRING","value":"GREDOS"},"target_publication_id":{"type":"STRING","value":"oai:http://gredos.usal.es/jspui:10366/73939"},"target_publication_author_list":{"type":"LIST_STRING","value":["Molina Abril, José Antonio","Pertíñez Izquierdo, Concepción"]},"provenance_publication_id_list":{"type":"LIST_STRING","value":["oai:gredos.usal.es:10366/73939"]},"provenance_datasource_id":{"type":"STRING","value":"10|opendoar____::daa96d9681a21445772454cbddf0cac1"},"target_publication_subject_list":{"type":"LIST_STRING","value":["Botánica","Plantas medicinales","Botany","Medicinal plants"]},"trust":{"type":"FLOAT","value":0.7826948},"target_publication_title":{"type":"STRING","value":"Aspectos fitogeográficos del género Glyceria R. 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Elasticity after thermocycling (1000, 3000, and 7000 cycles,  n \\u003d 15) was measured by three-point bending testing. Mean surface roughness (Ra) was determined after storage in the liquids mentioned above and thermocycling (n \\u003d 10). Results. Tukey\\u0027s HSD test (P \\u003c 0.05) revealed statistically significant color changes of PA in red wine (ΔE \\u003d 4.27 after 12 days, ΔE \\u003d 6.90 after 12 days) and coffee (ΔE \\u003d 3.93 after 36 days) but no color changes in PMMA. Elastic modulus of PA was 845 MPa and not affected by thermocycling (Tukey\\u0027s HSD test,  P \\u003e 0.81). Dry specimens showed significantly decreased elasticity (P \\u003c 0.001). Mean surface roughness (PA 0.20  μ m, PMMA 0.28  μ m) did not change significantly after thermocycling or storage (Mann-Whitney U-test,  0.16 \\u003c P \\u003c 0.65). Significance. PA exhibited a higher susceptibility to discoloration than PMMA. 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